Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilR   Type   Regulator
Locus tag   E4T55_RS14225 Genome accession   NZ_CP038273
Coordinates   3074979..3076313 (+) Length   444 a.a.
NCBI ID   WP_058501757.1    Uniprot ID   A0A0W0VUL7
Organism   Legionella israelensis strain Bercovier 4     
Function   regulate pilin expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 3069979..3081313
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E4T55_RS14195 (E4T55_14195) - 3069992..3070585 (-) 594 WP_058501762.1 flagellar biosynthetic protein FliR -
  E4T55_RS14200 (E4T55_14200) fliQ 3070582..3070854 (-) 273 WP_223168243.1 flagellar biosynthesis protein FliQ -
  E4T55_RS14205 (E4T55_14205) trpC 3071036..3071845 (-) 810 WP_058501760.1 indole-3-glycerol phosphate synthase TrpC -
  E4T55_RS14210 (E4T55_14210) trpD 3071842..3072861 (-) 1020 WP_058501759.1 anthranilate phosphoribosyltransferase -
  E4T55_RS14215 (E4T55_14215) - 3072969..3073205 (-) 237 WP_131780714.1 hypothetical protein -
  E4T55_RS14220 (E4T55_14220) - 3073390..3074982 (+) 1593 WP_058501769.1 ATP-binding protein -
  E4T55_RS14225 (E4T55_14225) pilR 3074979..3076313 (+) 1335 WP_058501757.1 sigma-54 dependent transcriptional regulator Regulator
  E4T55_RS14230 (E4T55_14230) - 3076631..3078994 (-) 2364 WP_058501756.1 penicillin-binding protein 1A -
  E4T55_RS14235 (E4T55_14235) - 3079185..3080189 (-) 1005 WP_058501755.1 hypothetical protein -

Sequence

Protein


Download         Length: 444 a.a.        Molecular weight: 49835.63 Da        Isoelectric Point: 7.4833

>NTDB_id=353073 E4T55_RS14225 WP_058501757.1 3074979..3076313(+) (pilR) [Legionella israelensis strain Bercovier 4]
MKKNKILVVDDEPDMRELLSLTLSRMGLDCDCAENYQQGINFIDNNPHYDLVLTDMRLPDGDGIEIVKHIQKHNLQIPAA
VITAYGNVEGAVNALKAGAFDYVSKPIDLPMLKDLVKTALSMQQKNQTEVLDGGKLVGDSAVMQNLRHNIRKLARSQAPV
FIQGESGVGKELVAQLIHANGPRSDKPFIPVNCGAIPTELMESEFFGHKKGSFTGAVSDKRGLFVAAHGGTLFLDEIAEL
PLSMQVKLLRAIQEKAIKPVGELNEISVDVRILSASHKNLLTEIESGRFRQDLYYRVNVIELRVPTLQERISDIPALSEH
ILKKLCKNQNRKPVKLAQNCIKKLQQYNYPRNVRELENILERALAMCEGETIHEEDLHIPKKSTQISPTLVEDAESLDGF
LLEQEKEIILNALEKTKWNRTAAARLLGISFRTLRYRLKKLNLD

Nucleotide


Download         Length: 1335 bp        

>NTDB_id=353073 E4T55_RS14225 WP_058501757.1 3074979..3076313(+) (pilR) [Legionella israelensis strain Bercovier 4]
ATGAAAAAAAACAAAATACTGGTTGTAGATGATGAGCCCGATATGCGTGAGTTGCTTTCACTTACACTTTCTCGTATGGG
CTTAGACTGTGATTGTGCGGAAAATTATCAGCAAGGAATTAATTTTATCGATAACAATCCTCACTATGACCTGGTGCTTA
CCGATATGCGTTTACCGGATGGTGATGGTATTGAAATTGTCAAACACATTCAAAAGCATAACCTGCAAATTCCTGCAGCT
GTTATCACGGCTTACGGGAATGTTGAAGGTGCTGTGAATGCTCTTAAAGCAGGAGCCTTTGATTATGTTTCAAAGCCTAT
TGATTTGCCTATGCTGAAAGATTTGGTCAAAACAGCTTTATCCATGCAGCAAAAAAATCAAACCGAGGTGCTGGATGGTG
GGAAATTGGTGGGTGACAGCGCTGTTATGCAGAATTTACGCCATAATATACGCAAGTTAGCCCGCAGCCAGGCACCTGTT
TTTATTCAGGGGGAGTCGGGAGTAGGTAAAGAATTGGTTGCCCAATTGATTCATGCCAATGGCCCTAGAAGTGATAAGCC
TTTTATTCCCGTGAACTGTGGAGCCATACCTACTGAATTAATGGAATCAGAATTTTTTGGCCATAAAAAGGGAAGTTTTA
CAGGAGCAGTCAGTGATAAGCGAGGTTTATTTGTCGCAGCCCATGGAGGGACTTTGTTTCTTGATGAAATCGCAGAGTTG
CCTTTATCAATGCAAGTTAAATTGTTGCGCGCTATTCAGGAGAAAGCCATAAAACCTGTGGGGGAATTAAATGAAATTTC
TGTAGATGTTCGTATACTCAGTGCCAGCCACAAAAATTTGCTGACTGAGATTGAGTCAGGACGTTTTCGCCAAGATTTAT
ATTATCGAGTTAATGTCATCGAACTTCGTGTACCTACTTTGCAGGAAAGAATATCTGACATTCCTGCTCTTTCTGAGCAT
ATATTGAAAAAGCTATGTAAAAATCAAAATAGAAAGCCAGTAAAACTGGCACAAAACTGTATTAAAAAATTACAGCAGTA
TAACTATCCCAGAAATGTGCGAGAGTTGGAAAATATTTTGGAACGTGCTTTGGCTATGTGTGAAGGTGAAACCATTCATG
AAGAAGACTTGCATATACCTAAAAAAAGCACACAAATTTCTCCTACACTGGTTGAAGATGCAGAAAGTCTGGATGGCTTT
CTGCTTGAACAGGAAAAAGAGATTATATTAAATGCATTGGAAAAAACAAAATGGAATCGTACAGCAGCCGCTCGTTTATT
AGGGATAAGCTTTCGGACACTTCGTTATCGATTAAAAAAACTTAATCTTGACTAG

Domains

Predicted by InterproScan.

Sigma-54 interaction domain (Sigma54_activat)

(136-302)

Bacterial regulatory protein, Fis family (HTH_8)

(403-441)

Response regulator receiver domain (Response_reg)

(6-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0W0VUL7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilR Pseudomonas aeruginosa PAK

56.6

100

0.57
  pilR Acinetobacter baumannii strain A118

49.565

100

0.514
  luxO Vibrio cholerae strain A1552

35.874

100

0.36

Multiple sequence alignment