Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   GN312_RS07380 Genome accession   NZ_CP046527
Coordinates   1352743..1353375 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain RM19259     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1347743..1358375
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GN312_RS07355 (GN312_07355) yheS 1347912..1349825 (+) 1914 WP_000634798.1 ABC transporter ATP-binding protein -
  GN312_RS07360 (GN312_07360) yheT 1349825..1350847 (+) 1023 WP_000057377.1 hydrolase -
  GN312_RS07365 (GN312_07365) yheU 1350841..1351059 (+) 219 WP_000907085.1 YheU family protein -
  GN312_RS07370 (GN312_07370) prkB 1351113..1351982 (+) 870 WP_001274677.1 phosphoribulokinase -
  GN312_RS07375 (GN312_07375) yhfA 1352037..1352441 (-) 405 WP_001148908.1 OsmC family protein -
  GN312_RS07380 (GN312_07380) crp 1352743..1353375 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  GN312_RS07385 (GN312_07385) yhfK 1353426..1355516 (+) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  GN312_RS07390 (GN312_07390) argD 1355583..1356803 (-) 1221 WP_000963819.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  GN312_RS07395 (GN312_07395) pabA 1356889..1357452 (-) 564 WP_000601867.1 aminodeoxychorismate synthase component 2 -
  GN312_RS07400 (GN312_07400) fic 1357484..1358086 (-) 603 WP_001280650.1 putative adenosine monophosphate-protein transferase Fic -
  GN312_RS07405 (GN312_07405) yhfG 1358076..1358243 (-) 168 WP_000736862.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=352999 GN312_RS07380 WP_000242755.1 1352743..1353375(+) (crp) [Escherichia coli strain RM19259]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=352999 GN312_RS07380 WP_000242755.1 1352743..1353375(+) (crp) [Escherichia coli strain RM19259]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCTGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTCAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTTGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467