Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   E4K03_RS14225 Genome accession   NZ_CP038262
Coordinates   2918706..2919413 (+) Length   235 a.a.
NCBI ID   WP_000203217.1    Uniprot ID   -
Organism   Acinetobacter baumannii strain LEV1449/17Ec     
Function   regulate competence development (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 2915555..2936406 2918706..2919413 within 0


Gene organization within MGE regions


Location: 2915555..2936406
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E4K03_RS14210 (E4K03_14210) - 2916786..2917328 (+) 543 Protein_2737 M23 family metallopeptidase -
  E4K03_RS14215 (E4K03_14215) - 2917325..2917750 (-) 426 WP_001026234.1 GNAT family N-acetyltransferase -
  E4K03_RS14220 (E4K03_14220) - 2917845..2918267 (-) 423 WP_001195082.1 OsmC family protein -
  E4K03_RS19710 - 2918346..2918465 (-) 120 Protein_2740 hypothetical protein -
  E4K03_RS14225 (E4K03_14225) crp 2918706..2919413 (+) 708 WP_000203217.1 cAMP-activated global transcriptional regulator CRP Regulator
  E4K03_RS14230 (E4K03_14230) - 2919574..2920623 (+) 1050 WP_001159800.1 NADP(H)-dependent aldo-keto reductase -
  E4K03_RS14235 (E4K03_14235) - 2920682..2921461 (-) 780 WP_001034598.1 M48 family metallopeptidase -
  E4K03_RS14240 (E4K03_14240) - 2921578..2921895 (-) 318 WP_000776215.1 hypothetical protein -
  E4K03_RS14245 (E4K03_14245) - 2922017..2923336 (-) 1320 WP_000517792.1 adenylosuccinate synthase -
  E4K03_RS14250 (E4K03_14250) - 2923401..2924567 (-) 1167 WP_109267427.1 ATP phosphoribosyltransferase regulatory subunit -
  E4K03_RS14255 (E4K03_14255) - 2924757..2925842 (-) 1086 WP_109267428.1 hypothetical protein -
  E4K03_RS14260 (E4K03_14260) gap 2926008..2927027 (-) 1020 WP_001188822.1 type I glyceraldehyde-3-phosphate dehydrogenase -
  E4K03_RS14265 (E4K03_14265) alaS 2927297..2929933 (+) 2637 WP_000199459.1 alanine--tRNA ligase -
  E4K03_RS14270 (E4K03_14270) - 2929999..2931279 (+) 1281 WP_001185176.1 aspartate kinase -
  E4K03_RS14275 (E4K03_14275) csrA 2931526..2931780 (+) 255 WP_000906487.1 carbon storage regulator CsrA -
  E4K03_RS14280 (E4K03_14280) rnhB 2931850..2932416 (-) 567 WP_000495834.1 ribonuclease HII -
  E4K03_RS14285 (E4K03_14285) - 2932482..2932871 (-) 390 WP_000735756.1 hypothetical protein -
  E4K03_RS14290 (E4K03_14290) - 2933111..2933662 (+) 552 WP_135013557.1 cytochrome b -
  E4K03_RS14295 (E4K03_14295) - 2933715..2934880 (+) 1166 WP_099349815.1 IS3 family transposase -
  E4K03_RS14300 (E4K03_14300) - 2935028..2936406 (+) 1379 WP_088360641.1 IS3-like element ISAba45 family transposase -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 26567.18 Da        Isoelectric Point: 4.6625

>NTDB_id=352879 E4K03_RS14225 WP_000203217.1 2918706..2919413(+) (crp) [Acinetobacter baumannii strain LEV1449/17Ec]
MTSNFSQLSTDALSPGQLPESVKALLKRAHINRYPKRTTIVDAGTESKSLYLILKGSVSIILREDDEREIVVAYLNPGDF
FGEMGLFEPNPQRTAEVRTRDVCEIAEISYDNFHELSKQYPDLSYAVFAQLVRRLKNTTRKMTDLAFIDVSGRIARCLID
LSSQPEAMILPNGRQIRITRQEIGRIVGCSREMVGRVLKTLEDQGMIQTDGKAILIFDTSLEETPVTDEDYDDEE

Nucleotide


Download         Length: 708 bp        

>NTDB_id=352879 E4K03_RS14225 WP_000203217.1 2918706..2919413(+) (crp) [Acinetobacter baumannii strain LEV1449/17Ec]
ATGACTTCAAATTTTTCACAACTCAGCACAGATGCTTTATCTCCGGGGCAACTACCTGAATCCGTTAAAGCATTGTTAAA
ACGTGCTCACATCAACAGATATCCAAAACGAACCACAATTGTTGATGCCGGAACAGAGTCAAAATCTTTATATTTAATTT
TAAAAGGCTCAGTTTCAATTATTTTACGTGAAGACGATGAACGTGAAATTGTTGTGGCATATTTGAATCCTGGTGACTTC
TTTGGGGAAATGGGGCTTTTCGAACCGAACCCTCAACGTACAGCTGAAGTTCGTACCCGTGATGTCTGTGAAATTGCAGA
AATTTCATATGACAACTTCCACGAACTGAGCAAACAGTATCCAGATCTCAGCTATGCCGTTTTCGCGCAACTCGTTCGTC
GTTTAAAAAATACAACTCGTAAAATGACCGATCTTGCATTTATTGATGTGTCAGGTCGTATTGCGCGTTGCTTAATCGAC
CTATCTTCACAACCAGAAGCAATGATCTTGCCGAATGGCCGTCAAATTCGTATTACTCGACAAGAGATTGGACGCATTGT
CGGGTGTTCACGAGAAATGGTTGGCCGTGTATTAAAGACCTTAGAAGATCAAGGTATGATTCAAACTGACGGTAAAGCTA
TTCTAATTTTTGATACTTCATTAGAAGAAACCCCAGTCACTGACGAAGACTACGATGACGAAGAATAA

Domains

Predicted by InterproScan.

Crp-like helix-turn-helix domain (HTH_Crp_2)

(152-218)

Cyclic nucleotide-binding domain (cNMP_binding)

(33-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Acinetobacter baumannii D1279779

99.574

100

0.996
  crp Vibrio cholerae strain A1552

47.343

88.085

0.417
  crp Haemophilus influenzae Rd KW20

48.705

82.128

0.4

Multiple sequence alignment