Detailed information NTG0352856

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: GOM47_RS08880
• Genome accession: NZ_CP046524
• Coordinates: 1776411..1778945 (-)
• Length: 844 a.a.
• NCBI ID: WP_235080572.1
• Uniprot ID: -
• Organism: Streptococcus oralis strain SOT
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 1771411..1783945

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GOM47_RS08855 (GOM47_08860)	ruvA	1771915..1772508 (-)	594	WP_235080567.1	Holliday junction branch migration protein RuvA	Machinery gene
GOM47_RS08860 (GOM47_08865)	-	1772664..1773164 (+)	501	WP_235080568.1	helix-turn-helix domain-containing protein	-
GOM47_RS08865 (GOM47_08870)	hexB	1773317..1775266 (-)	1950	WP_235080569.1	DNA mismatch repair endonuclease MutL	Machinery gene
GOM47_RS08870 (GOM47_08875)	-	1775475..1775915 (+)	441	WP_235080570.1	LytTR family DNA-binding domain-containing protein	-
GOM47_RS08875 (GOM47_08880)	-	1775912..1776370 (+)	459	WP_235080571.1	DUF3021 domain-containing protein	-
GOM47_RS08880 (GOM47_08885)	hexA	1776411..1778945 (-)	2535	WP_235080572.1	DNA mismatch repair protein MutS	Machinery gene
GOM47_RS08885 (GOM47_08890)	argR	1778996..1779442 (-)	447	WP_001227366.1	arginine repressor	-
GOM47_RS08890 (GOM47_08895)	argS	1779590..1781278 (+)	1689	WP_235080573.1	arginine--tRNA ligase	-
GOM47_RS08895 (GOM47_08900)	-	1781796..1782041 (+)	246	WP_235080574.1	MarR family transcriptional regulator	-
GOM47_RS08900 (GOM47_08905)	-	1782239..1783501 (+)	1263	WP_235080575.1	NRAMP family divalent metal transporter	-

Sequence

Protein

• Length: 844 a.a.
• Molecular weight: 94797.24 Da
• Isoelectric Point: 4.8531

>NTDB_id=352856 GOM47_RS08880 WP_235080572.1 1776411..1778945(-) (hexA) [Streptococcus oralis strain SOT]
MTTEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAAQILEISLTSRNKNAENPIPMAGVPYHSAQQYIDVLI
EQGYKVAIAEQMEDPKQAVGVVKREVVQVITPGTVVDSSKPDSQNNFLVALDRDGNQFGLAYMDLVTGDFYVTGLLDFTL
VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKEAFEDLHLLDSRLAAVEQAAASKLLQYVHRTQMRELNHLKP
VIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLFWLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFF
ERSDLTDSLKGVYDIERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPALAYLIEQLDGIPELESLISAAIAP
EAPHVITEGGIIRTGFDETLDKYRRVLREGTSWIAEIEAKERENSGISTLKIDYNKKDGYYFHVTNSQLGNVPAHFFRKA
TLKNSERFGTEELARIEGDMLEAREKSANLEYEIFMRIREEVSKYIQRLQALAQGIATIDVLQSLAVVAETQHLIRPEFG
DDSQIAIQKGRHAVVEKVMGAQTYIPNTIQMSEDTSIQLITGPNMSGKSTYMRQLAMMAVMAQMGSYVPAESAYLPIFDA
IFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDELGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHEL
TSLESSLEHLVNVHVATLEQDGQVTFLHKIEPGPADKSYGIHVAKIAGLPAELLARADKILTQLENQGTESPAPMRQTSA
VTEQISLFDTPAEHPILAELAQLDVYNMTPMQAMNVLVEFKQKL

Nucleotide

• Length: 2535 bp

>NTDB_id=352856 GOM47_RS08880 WP_235080572.1 1776411..1778945(-) (hexA) [Streptococcus oralis strain SOT]
ATGACGACAGAAAAACTATCACCTGGTATGCAGCAGTATGTGGATATTAAAAAGCAATATCCAGATGCTTTTTTGCTCTT
TCGGATGGGTGATTTTTATGAGCTGTTTTATGAAGATGCGGTCAATGCGGCGCAGATTTTAGAGATTTCACTGACCAGTC
GTAATAAAAATGCAGAAAATCCGATACCCATGGCAGGCGTTCCCTATCATTCTGCCCAGCAGTATATCGATGTTCTGATT
GAGCAGGGCTATAAGGTAGCCATAGCCGAGCAGATGGAGGATCCCAAACAAGCGGTTGGGGTTGTCAAGCGAGAGGTGGT
TCAGGTCATCACCCCCGGTACAGTGGTTGATAGTAGTAAGCCCGATAGTCAGAACAATTTCTTGGTTGCCTTAGATCGTG
ATGGCAATCAATTTGGCTTGGCTTATATGGATCTAGTGACAGGTGATTTTTATGTGACAGGTTTATTGGATTTTACTCTC
GTTTGTGGGGAAATCCGTAACCTCAAGGCTCGAGAAGTGGTGCTGGGTTATGACTTGTCTGAGGAAGAAGAACAAATCCT
CAGCCGTCAGATGAATCTGGTACTTTCTTATGAAAAAGAAGCCTTTGAGGACCTTCATTTACTGGATTCACGACTGGCAG
CTGTGGAGCAAGCGGCAGCTAGTAAGCTCCTCCAGTATGTTCACCGGACCCAGATGCGGGAATTGAACCACCTCAAACCT
GTTATCCGCTATGAAATCAAAGATTTCTTGCAGATGGATTATGCTACTAAGGCTAGTTTGGATTTGGTTGAGAATGCCCG
TTCAGGCAAGAAGCAAGGCAGTCTTTTCTGGCTTTTGGATGAAACCAAAACGGCTATGGGTATGCGGCTCTTACGTTCTT
GGATTCATCGTCCCTTGATTGATAAGGAGCGAATCGTCCAGCGTCAAGAGGTGGTGCAGGTCTTTCTTGACCACTTCTTT
GAGCGTAGTGATTTAACGGACAGTCTCAAAGGTGTTTATGATATCGAACGCTTGGCTAGTCGGGTTTCTTTTGGCAAGAC
CAATCCCAAGGATCTCTTGCAGTTAGCTACTACATTGTCTAGTGTGCCACGTATTCGAGCAATATTAGAAGGGATGGAGC
AACCTGCTCTAGCCTATCTCATCGAACAGTTGGATGGAATCCCTGAGTTGGAGAGCTTGATTAGCGCAGCGATTGCTCCT
GAGGCTCCTCATGTGATTACGGAAGGTGGCATTATCCGAACGGGATTTGATGAGACTTTGGATAAATACCGTCGAGTGCT
CAGAGAAGGGACCAGTTGGATTGCAGAGATTGAGGCTAAGGAGAGAGAAAACTCTGGTATCAGCACGCTCAAGATTGACT
ACAATAAAAAAGATGGCTACTATTTCCATGTGACCAATTCGCAACTGGGGAATGTGCCAGCCCACTTTTTCCGCAAGGCA
ACGCTGAAAAACTCGGAACGCTTTGGGACTGAGGAATTGGCCCGTATCGAGGGGGATATGTTGGAGGCGCGTGAGAAGTC
AGCCAACCTAGAGTACGAAATTTTTATGCGTATCCGAGAGGAAGTCAGTAAGTATATCCAGCGTTTGCAGGCTCTAGCCC
AAGGAATTGCGACGATTGATGTTTTGCAAAGTCTGGCGGTTGTAGCTGAAACCCAGCATTTGATTCGACCTGAGTTCGGT
GACGACTCACAAATCGCTATCCAGAAAGGTCGCCATGCTGTCGTCGAAAAGGTCATGGGAGCGCAGACCTATATTCCAAA
TACGATTCAGATGTCAGAAGATACCAGCATTCAACTGATTACGGGACCCAACATGAGCGGGAAGTCCACCTATATGCGCC
AACTAGCCATGATGGCGGTTATGGCCCAGATGGGTTCCTATGTTCCTGCTGAGAGCGCCTACTTACCGATTTTTGATGCC
ATCTTTACCCGTATCGGAGCGGCAGATGACTTGGTTTCAGGTCAATCAACCTTCATGGTGGAGATGATGGAGGCCAACAA
TGCCATTTCGCATGCGACCAAGAATTCCTTGATTCTCTTTGATGAGTTAGGTCGAGGAACTGCGACTTATGATGGGATGG
CTCTTGCCCAGTCCATCATCGAATACATTCATGAACATATCGGAGCCAAAACCCTCTTTGCGACCCACTACCATGAGTTG
ACCAGTCTGGAGTCTAGCTTGGAACACTTGGTCAATGTTCATGTGGCAACCTTGGAGCAGGATGGGCAGGTTACCTTCCT
TCACAAGATCGAACCAGGACCAGCTGACAAATCCTACGGTATCCATGTTGCTAAGATTGCTGGTTTACCAGCAGAACTTT
TAGCAAGGGCGGATAAGATTTTGACCCAGCTAGAGAATCAAGGAACAGAAAGTCCAGCTCCAATGAGGCAAACAAGTGCC
GTTACGGAACAGATTTCACTCTTTGATACGCCAGCAGAACATCCTATCCTAGCAGAATTAGCTCAGCTGGATGTGTACAA
TATGACGCCTATGCAAGCTATGAATGTCTTAGTTGAGTTCAAACAAAAATTATAA

Domains

Predicted by InterProScan.

• MutS family domain IV (MutS_IV) (415-505)

• MutS domain III (MutS_III) (256-546)

• MutS domain I (MutS_I) (8-118)

• MutS domain V (MutS_V) (599-785)

• MutS domain II (MutS_II) (126-239)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	95.972	100	0.96
mutS	Pseudomonas stutzeri strain ATCC 17587	37.033	100	0.376