Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   GOM47_RS08865 Genome accession   NZ_CP046524
Coordinates   1773317..1775266 (-) Length   649 a.a.
NCBI ID   WP_235080569.1    Uniprot ID   -
Organism   Streptococcus oralis strain SOT     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1768317..1780266
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GOM47_RS08835 (GOM47_08840) - 1768763..1769440 (+) 678 WP_235080564.1 DUF1129 domain-containing protein -
  GOM47_RS08840 (GOM47_08845) - 1769578..1770615 (+) 1038 WP_235080565.1 S66 peptidase family protein -
  GOM47_RS08845 (GOM47_08850) - 1770661..1771344 (-) 684 WP_235081287.1 CPBP family intramembrane glutamic endopeptidase -
  GOM47_RS08850 (GOM47_08855) - 1771345..1771905 (-) 561 WP_235080566.1 DNA-3-methyladenine glycosylase I -
  GOM47_RS08855 (GOM47_08860) ruvA 1771915..1772508 (-) 594 WP_235080567.1 Holliday junction branch migration protein RuvA Machinery gene
  GOM47_RS08860 (GOM47_08865) - 1772664..1773164 (+) 501 WP_235080568.1 helix-turn-helix domain-containing protein -
  GOM47_RS08865 (GOM47_08870) hexB 1773317..1775266 (-) 1950 WP_235080569.1 DNA mismatch repair endonuclease MutL Machinery gene
  GOM47_RS08870 (GOM47_08875) - 1775475..1775915 (+) 441 WP_235080570.1 LytTR family DNA-binding domain-containing protein -
  GOM47_RS08875 (GOM47_08880) - 1775912..1776370 (+) 459 WP_235080571.1 DUF3021 domain-containing protein -
  GOM47_RS08880 (GOM47_08885) hexA 1776411..1778945 (-) 2535 WP_235080572.1 DNA mismatch repair protein MutS Machinery gene
  GOM47_RS08885 (GOM47_08890) argR 1778996..1779442 (-) 447 WP_001227366.1 arginine repressor -

Sequence

Protein


Download         Length: 649 a.a.        Molecular weight: 73294.69 Da        Isoelectric Point: 5.4483

>NTDB_id=352855 GOM47_RS08865 WP_235080569.1 1773317..1775266(-) (hexB) [Streptococcus oralis strain SOT]
MSHIIELPEVLANQIAAGEVIERPASVVKELVENAIDAGSSQIIIEIEEAGLKKIQITDNGHGIAHDEVELALRRHATSK
IKNQADLFRIRTLGFRGEALPSIASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLASAKKMIEIENSDLDFEITGFVSLP
ELTRANRNYISLFINGRYIKNFLLNRAILDGYGSKLMVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMALVSE
AISNSLKEQALIPDALENLAKSTVRNRQKVEQTTLPLKENTLYYEKTELSRPSQAEVADHQVELTEEGKDLTLFAKETLD
QLTKPGKLHFAERKPASYDQLDHPELDLASIDKAYDKLEREEASSFPELEFFGQMHGTYLFAQGRDGLYIIDQHAAQERV
KYEEYRESIGNVDQSQQQLLVPYIFEFPADDALRLRERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCD
MLLLTKEVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHFTKSDMEKMFRRIQENH
TSLRELGKY

Nucleotide


Download         Length: 1950 bp        

>NTDB_id=352855 GOM47_RS08865 WP_235080569.1 1773317..1775266(-) (hexB) [Streptococcus oralis strain SOT]
ATGTCTCATATTATTGAATTACCAGAGGTGCTGGCAAACCAGATTGCGGCAGGGGAGGTTATCGAACGTCCTGCTAGTGT
GGTCAAAGAGTTGGTAGAAAATGCCATTGACGCCGGTTCTAGCCAGATTATCATTGAGATCGAGGAAGCTGGACTCAAGA
AAATCCAAATCACTGATAATGGTCATGGAATTGCCCACGATGAGGTGGAATTGGCCTTGCGTCGCCATGCGACCAGTAAG
ATAAAAAATCAAGCAGACCTCTTTCGGATTCGGACGCTCGGCTTTCGAGGTGAAGCTCTGCCCTCTATCGCTTCTGTTAG
TGTGCTGACTCTGTTGACGGCAGTAGATGGTGCGAGTCATGGGACCAAGCTCGTTGCGCGTGGGGGAGAAGTTGAGGAAG
TCATCCCAGCGACTAGTCCTGTGGGGACCAAAGTTTGTGTGGAGGACCTCTTTTTCAACACACCTGCCCGCCTCAAGTAT
ATGAAGAGCCAGCAAGCGGAGCTGTCTCATATCATTGATATTGTCAACCGTCTGGGCTTGGCCCATCCTGAGATTTCCTT
CAGTTTGATTAGTGATGGCAAGGAAATGACGCGGACAGCAGGGACTGGTCAACTACGCCAAGCCATCGCAGGGATTTACG
GTTTGGCGAGTGCCAAGAAGATGATTGAAATTGAGAACTCTGACTTAGATTTCGAAATTACAGGTTTTGTGTCTCTGCCT
GAGTTAACCCGAGCAAATCGTAACTATATCAGCCTCTTCATCAATGGCCGTTATATCAAGAACTTCTTGCTCAATCGCGC
TATTCTTGACGGTTATGGAAGCAAGCTTATGGTAGGTCGCTTTCCACTGGCTGTCATTCACATCCATATCGATCCTTATC
TGGCTGATGTCAATGTCCATCCAACCAAACAAGAAGTGCGGATTTCCAAGGAAAAAGAGCTGATGGCGCTGGTTTCAGAA
GCTATTTCTAACAGTCTCAAGGAGCAAGCCTTGATACCAGATGCCTTGGAGAATCTTGCCAAGTCGACCGTGCGCAATCG
TCAAAAGGTGGAGCAAACTACTCTCCCGCTCAAAGAAAATACGCTCTACTATGAAAAAACAGAACTCTCAAGACCTAGTC
AAGCTGAGGTTGCTGATCATCAGGTTGAATTAACTGAGGAAGGAAAAGATTTGACCTTATTTGCCAAGGAAACCTTGGAC
CAGTTGACCAAGCCAGGAAAGCTCCATTTTGCAGAGAGAAAGCCGGCTAGCTATGACCAACTAGATCATCCAGAGTTAGA
TCTTGCTAGCATCGATAAGGCTTATGACAAGCTGGAGCGAGAAGAAGCATCCAGCTTCCCAGAGTTGGAGTTTTTCGGAC
AGATGCATGGGACTTATCTCTTTGCCCAAGGGCGAGATGGACTTTACATCATAGATCAGCACGCTGCTCAGGAACGAGTC
AAGTATGAGGAATACCGTGAGAGTATTGGTAATGTTGACCAGAGCCAGCAGCAACTCCTAGTGCCCTACATCTTTGAATT
CCCAGCGGATGATGCCCTTCGTCTCAGGGAAAGAATGCCTCTCTTAGAGGAAGTGGGCGTCTTTCTAGCAGAGTATGGAG
AAAATCAATTTATCCTGCGTGAACATCCTATTTGGATGGCAGAAGAAGAGATTGAGTCAGGCATCTATGAGATGTGCGAC
ATGCTGCTCTTGACCAAGGAAGTTTCGATTAAGAAATACCGAGCAGAGCTGGCCATCATGATGTCTTGTAAGCGGTCGAT
CAAGGCCAACCATCGTATCGATGACCATTCAGCTCGACAGCTCCTTTATCAGCTCTCCCAATGTGACAATCCCTATAACT
GTCCACATGGACGTCCTGTTTTGGTGCATTTTACCAAGTCAGACATGGAAAAAATGTTCCGACGCATTCAGGAAAATCAT
ACGAGCCTACGAGAGTTGGGGAAATATTAA

Domains

Predicted by InterProScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-107)

MutL C terminal dimerisation domain (MutL_C)

(450-592)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

97.072

100

0.971