Detailed information NTG0352845

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: GOM47_RS08160
• Genome accession: NZ_CP046524
• Coordinates: 1623937..1626042 (-)
• Length: 701 a.a.
• NCBI ID: WP_235080491.1
• Uniprot ID: -
• Organism: Streptococcus oralis strain SOT
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 1618937..1631042

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GOM47_RS08130 (GOM47_08125)	-	1619208..1620239 (-)	1032	WP_235080485.1	sensor histidine kinase	-
GOM47_RS08135 (GOM47_08130)	-	1620206..1620904 (-)	699	WP_235080486.1	response regulator transcription factor	-
GOM47_RS08140 (GOM47_08135)	-	1620917..1621639 (-)	723	WP_235080487.1	lantibiotic ABC transporter permease	-
GOM47_RS08145 (GOM47_08140)	-	1621639..1622427 (-)	789	WP_235080488.1	lantibiotic ABC transporter permease	-
GOM47_RS08150 (GOM47_08145)	-	1622429..1623136 (-)	708	WP_235080489.1	ABC transporter ATP-binding protein	-
GOM47_RS08155 (GOM47_08150)	-	1623400..1623882 (+)	483	WP_235080490.1	S-ribosylhomocysteine lyase	-
GOM47_RS08160 (GOM47_08155)	clpE	1623937..1626042 (-)	2106	WP_235080491.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
GOM47_RS08165 (GOM47_08160)	pflB	1626436..1628751 (-)	2316	WP_038804146.1	formate C-acetyltransferase	-
GOM47_RS08170 (GOM47_08165)	dinB	1628988..1630049 (+)	1062	WP_235080492.1	DNA polymerase IV	-
GOM47_RS08175 (GOM47_08170)	-	1630081..1630926 (-)	846	WP_000273572.1	undecaprenyl-diphosphate phosphatase	-

Sequence

Protein

• Length: 701 a.a.
• Molecular weight: 77453.17 Da
• Isoelectric Point: 4.7685

>NTDB_id=352845 GOM47_RS08160 WP_235080491.1 1623937..1626042(-) (clpE) [Streptococcus oralis strain SOT]
MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEFAHYRATGQLPGNAESDAQMQQHASGMKQDGVLAKLG
RNLTAEAREGKLDPVIGRNKEIQETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKPALSRGELTVIGATTQDEYRNTI
LKNAALARRFNEVKVNAPSAEDTFKILQGIRDLYQQHHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAA
QHPVTDVHAVEREIEAEKDKQEKAVEAEDFEAALNAKTRIAELEKKIENHTEDMKVTASVNDVAESVERMTGIPVSQMGA
SDIERLKDMAHRLEHKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSVLFVGPTGVGKTELAKQLALDMFGTKDAIIRLD
MSEYSDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNT
VIIATSNAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLNKEDLSKIVDLMLAEVNQTLAKKDIDLEVS
QAAKDFITEEGYDEVMGVRPLRRVVEQQIRDKVTDFHLDHLDAKHLEADMEDGVLVIREKA

Nucleotide

• Length: 2106 bp

>NTDB_id=352845 GOM47_RS08160 WP_235080491.1 1623937..1626042(-) (clpE) [Streptococcus oralis strain SOT]
ATGAACAACAACTTTAATAACTTTAACAACATGGATGATTTATTTAACCAATTGATGGGTGGCATGCGAGGATACAGTTC
TGAAAACCGTCGCTACTTGATTAATGGACGTGAAGTGACACCTGAGGAATTTGCTCACTATCGTGCAACTGGTCAATTGC
CAGGAAATGCAGAATCTGATGCGCAAATGCAACAACACGCTTCAGGTATGAAACAAGACGGTGTCCTTGCTAAACTAGGT
CGTAACTTGACAGCGGAAGCTCGTGAGGGCAAGTTGGATCCTGTTATCGGACGAAACAAGGAAATTCAAGAAACATCTGA
AATCCTCTCACGTCGTACGAAAAATAATCCTGTTCTAGTCGGAGATGCAGGTGTTGGTAAGACAGCCGTTGTCGAAGGTC
TAGCACAAGCGATTGTGAATGGAGATGTTCCGGCAGCCATCAAGAACAAGGAAATTATTTCTATTGATATCTCAGGTCTT
GAGGCTGGTACTCAATACCGTGGTAGCTTTGAAGAAAACGTTCAAAACCTAGTCAACGAGGTGAAAGAAGCAGGGAATAT
TATCCTCTTCTTTGATGAAATTCATCAAATTCTCGGTGCTGGTAGCACTGGTGGAGACAGTGGCTCCAAGGGGCTTGCGG
ACATTCTCAAGCCAGCTCTCTCTCGTGGTGAGTTGACTGTTATTGGGGCAACGACTCAAGACGAATACCGTAACACTATC
TTAAAGAATGCAGCTCTTGCTCGTCGTTTCAACGAAGTCAAGGTCAATGCTCCTTCAGCAGAGGATACCTTTAAAATCCT
TCAAGGAATTCGTGATCTTTATCAACAACACCACAATGTTATCTTGCCAGACGAAGTCTTGAAAGCAGCAGTGGATTATT
CTGTCCAATACATTCCTCAACGTAGCTTGCCAGATAAGGCCATTGACCTTGTCGATGTAACAGCTGCTCACTTGGCAGCT
CAACATCCAGTAACAGATGTTCATGCTGTCGAACGGGAAATCGAGGCAGAAAAGGACAAGCAAGAAAAAGCAGTTGAGGC
AGAAGATTTCGAAGCAGCTCTTAATGCTAAAACACGCATTGCAGAATTAGAAAAGAAAATCGAAAACCACACAGAAGATA
TGAAGGTGACTGCGAGTGTCAACGATGTGGCTGAATCTGTAGAACGTATGACTGGTATTCCGGTATCACAAATGGGAGCA
TCAGACATCGAACGTTTGAAAGATATGGCTCATCGTTTGGAACACAAGGTTATCGGCCAAGATAAGGCAGTAGAAGCAGT
GGCTCGTGCTATCCGTCGTAACCGTGCAGGATTTGATGAAGGCAATCGCCCAATCGGTAGCGTCCTCTTTGTAGGGCCTA
CTGGGGTTGGGAAGACCGAGCTTGCTAAGCAATTGGCGCTCGATATGTTTGGAACCAAGGATGCGATTATCCGTTTGGAT
ATGTCTGAATATAGTGACCGCACAGCTGTTTCTAAGTTAATCGGTACAACAGCAGGTTATGTGGGGTATGATGACAATAG
CAATACCTTGACAGAACGAGTTCGTCGTAATCCATACTCTATCATTCTCTTGGACGAAATTGAAAAGGCTGATCCTCAAG
TAATCACCCTCCTCCTCCAAGTCTTGGATGATGGTCGTTTGACAGATGGCCAAGGAAATACCGTGAACTTCAAGAACACT
GTCATTATCGCGACATCAAATGCTGGATTTGGCTATGAAGCCAACTTGACAGAAGATGCAGATAAACCAGAGTTGATGGA
TCGCTTGAAACCATTCTTCCGTCCAGAGTTTCTTAACCGCTTTAACGCAGTTATCGAGTTCTCACACTTAAATAAGGAAG
ACCTTTCTAAGATTGTGGACTTGATGTTGGCTGAAGTAAACCAAACCTTGGCTAAGAAAGATATTGATTTGGAAGTCAGC
CAAGCAGCTAAGGACTTTATCACAGAAGAAGGTTATGACGAAGTCATGGGTGTTCGTCCTCTCCGACGCGTAGTCGAACA
ACAAATCCGTGATAAGGTGACGGACTTCCACTTGGATCACCTAGATGCTAAACATCTGGAAGCAGATATGGAAGATGGCG
TTTTGGTCATTCGAGAAAAAGCCTAA

Domains

Predicted by InterProScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (443-603)

• ATPase family associated with various cellular activities (AAA) (AAA) (118-250)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (610-680)

• AAA lid domain (AAA_lid_9) (259-354)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	50.311	91.869	0.462
clpC	Lactococcus lactis subsp. cremoris KW2	50	91.298	0.456
clpE	Streptococcus pneumoniae D39	48.819	90.585	0.442
clpE	Streptococcus pneumoniae R6	48.819	90.585	0.442
clpE	Streptococcus pneumoniae Rx1	48.819	90.585	0.442
clpE	Streptococcus pneumoniae TIGR4	48.819	90.585	0.442
clpC	Bacillus subtilis subsp. subtilis str. 168	44.992	92.582	0.417
clpC	Streptococcus pneumoniae D39	42.949	89.016	0.382
clpC	Streptococcus pneumoniae Rx1	42.949	89.016	0.382
clpC	Streptococcus pneumoniae TIGR4	42.788	89.016	0.381
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	42.95	88.017	0.378
clpC	Streptococcus thermophilus LMD-9	42.95	88.017	0.378
clpC	Streptococcus thermophilus LMG 18311	42.788	88.017	0.377
clpC	Streptococcus mutans UA159	41.909	88.16	0.369