Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   GOM47_RS07935 Genome accession   NZ_CP046524
Coordinates   1563939..1564571 (-) Length   210 a.a.
NCBI ID   WP_235080449.1    Uniprot ID   -
Organism   Streptococcus oralis strain SOT     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1558939..1569571
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GOM47_RS07920 (GOM47_07915) recD/recD2/recDB 1559340..1561709 (+) 2370 WP_235080446.1 ATP-dependent RecD-like DNA helicase Machinery gene
  GOM47_RS07925 (GOM47_07920) tig 1561908..1563191 (-) 1284 WP_235080447.1 trigger factor -
  GOM47_RS07930 (GOM47_07925) - 1563282..1563938 (-) 657 WP_235080448.1 DNA alkylation repair protein -
  GOM47_RS07935 (GOM47_07930) vraR 1563939..1564571 (-) 633 WP_235080449.1 response regulator transcription factor Regulator
  GOM47_RS07940 (GOM47_07935) - 1564582..1565580 (-) 999 WP_235080450.1 sensor histidine kinase -
  GOM47_RS07945 (GOM47_07940) liaF 1565577..1566275 (-) 699 WP_235080451.1 cell wall-active antibiotics response protein LiaF -
  GOM47_RS07950 (GOM47_07945) fni 1566394..1567395 (-) 1002 WP_235080452.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  GOM47_RS07955 (GOM47_07950) - 1567379..1568386 (-) 1008 WP_235080453.1 phosphomevalonate kinase -
  GOM47_RS07960 (GOM47_07955) mvaD 1568373..1569326 (-) 954 WP_235080454.1 diphosphomevalonate decarboxylase -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23714.27 Da        Isoelectric Point: 4.8067

>NTDB_id=352839 GOM47_RS07935 WP_235080449.1 1563939..1564571(-) (vraR) [Streptococcus oralis strain SOT]
MKILLVDDHEMVRLGLKSYFDLQEDVEVVGEAANGSQGIDLALELRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIV
TSYLDNEKIMPVLNAGARGYMLKTSSADELLHAVRKVAAGELAIEQEVSKKVEYHRNHIELHEDLTARERDVLQLIAKGY
ENQRIADELFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVRQEDF

Nucleotide


Download         Length: 633 bp        

>NTDB_id=352839 GOM47_RS07935 WP_235080449.1 1563939..1564571(-) (vraR) [Streptococcus oralis strain SOT]
ATGAAAATTTTACTGGTAGATGACCATGAAATGGTCCGATTGGGCTTGAAAAGCTACTTTGACCTCCAAGAGGATGTAGA
AGTTGTGGGCGAGGCAGCCAATGGATCTCAAGGTATTGACTTGGCCTTGGAATTGCGTCCAGATGTTATTGTCATGGATA
TCGTCATGCCTGAGATGAATGGGATTGATGCAACCCTGGCTATTCTCAAAGAATGGCCTGAAGCCAAGATTTTGATTGTG
ACCTCTTACCTAGACAATGAAAAAATCATGCCTGTCTTAAACGCGGGTGCTAGGGGCTATATGCTCAAAACTTCAAGTGC
GGATGAATTGCTGCACGCTGTTCGTAAGGTTGCCGCTGGTGAGCTTGCTATTGAACAAGAGGTCAGCAAGAAGGTCGAAT
ACCACCGCAATCATATCGAACTTCATGAGGATCTGACTGCGCGTGAGCGAGATGTGCTTCAACTCATCGCTAAGGGCTAT
GAAAATCAGCGCATCGCAGATGAGCTCTTCATCTCCCTCAAGACGGTCAAGACCCATGTATCCAACATCCTAGCCAAGCT
TGAGGTCAGCGATCGCACTCAGGCTGCAGTCTATGCCTTTCAGCACCACTTGGTCAGGCAGGAGGATTTTTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(145-199)

Response regulator receiver domain (Response_reg)

(3-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

51.691

98.571

0.51
  degU Bacillus subtilis subsp. subtilis str. 168

38.393

100

0.41