Detailed information    

insolico Bioinformatically predicted

Overview

Name   ruvA   Type   Machinery gene
Locus tag   MGAS1882_RS08245 Genome accession   NC_017053
Coordinates   1699322..1699918 (-) Length   198 a.a.
NCBI ID   WP_002992186.1    Uniprot ID   P0DF49
Organism   Streptococcus pyogenes MGAS1882     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1694322..1704918
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MGAS1882_RS08210 (MGAS1882_1701) - 1694382..1694687 (-) 306 WP_002982199.1 DUF1292 domain-containing protein -
  MGAS1882_RS08215 (MGAS1882_1702) ruvX 1694699..1695118 (-) 420 WP_002982196.1 Holliday junction resolvase RuvX -
  MGAS1882_RS08220 (MGAS1882_1703) - 1695115..1695384 (-) 270 WP_002982194.1 IreB family regulatory phosphoprotein -
  MGAS1882_RS08225 (MGAS1882_1704) spx 1695498..1695896 (-) 399 WP_002982188.1 transcriptional regulator Spx -
  MGAS1882_RS08230 (MGAS1882_1705) recA 1696187..1697323 (-) 1137 WP_014407932.1 recombinase RecA Machinery gene
  MGAS1882_RS08235 (MGAS1882_1706) cinA 1697412..1698683 (-) 1272 WP_011285266.1 competence/damage-inducible protein A Machinery gene
  MGAS1882_RS08240 (MGAS1882_1707) - 1698752..1699312 (-) 561 WP_010922755.1 DNA-3-methyladenine glycosylase I -
  MGAS1882_RS08245 (MGAS1882_1708) ruvA 1699322..1699918 (-) 597 WP_002992186.1 Holliday junction branch migration protein RuvA Machinery gene
  MGAS1882_RS08250 (MGAS1882_1709) - 1699920..1701140 (-) 1221 WP_014407934.1 MDR family MFS transporter -
  MGAS1882_RS08255 (MGAS1882_1710) hexB 1701151..1703133 (-) 1983 WP_014407935.1 DNA mismatch repair endonuclease MutL Machinery gene
  MGAS1882_RS08260 (MGAS1882_1711) - 1703228..1704373 (-) 1146 WP_041174352.1 tyrosine-type recombinase/integrase -

Sequence

Protein


Download         Length: 198 a.a.        Molecular weight: 21879.26 Da        Isoelectric Point: 6.8838

>NTDB_id=35264 MGAS1882_RS08245 WP_002992186.1 1699322..1699918(-) (ruvA) [Streptococcus pyogenes MGAS1882]
MYDYIKGQLTKITAKYIVVEANGLGYMINVANPYSFTDSVNQLVTIYLHQVIREDAHLLFGFHTEDEKDVFLKLISVSGI
GPTTALAIVAVDDNEGLVNAIDNSDIKYLMKFPKIGKKTAQQMVLDLAGKFVEAPQETGHTKARSNKAGNTQLDEAIEAL
LALGYKAKELKKIRAFFEGTSETAEQYIKSALKLLMKG

Nucleotide


Download         Length: 597 bp        

>NTDB_id=35264 MGAS1882_RS08245 WP_002992186.1 1699322..1699918(-) (ruvA) [Streptococcus pyogenes MGAS1882]
ATGTACGATTATATTAAAGGTCAATTGACCAAAATTACGGCAAAATACATTGTCGTTGAAGCTAATGGATTGGGCTACAT
GATTAATGTTGCCAATCCTTATAGCTTTACAGATAGTGTCAACCAATTGGTAACCATTTATCTGCATCAAGTGATTCGTG
AGGATGCTCACCTGTTGTTTGGGTTTCACACGGAAGATGAAAAAGATGTTTTTCTGAAATTAATTTCTGTATCAGGTATT
GGTCCGACAACAGCTCTTGCTATTGTGGCAGTTGATGATAATGAGGGACTTGTGAATGCCATTGATAACAGTGACATTAA
GTACCTAATGAAATTTCCTAAAATTGGTAAAAAAACAGCGCAGCAAATGGTTCTTGACTTAGCTGGCAAATTTGTGGAGG
CTCCACAAGAGACTGGTCATACCAAAGCGCGCAGCAATAAAGCAGGCAATACTCAACTGGACGAAGCGATTGAAGCCCTC
CTTGCTCTCGGTTATAAAGCAAAAGAGCTGAAAAAAATTCGTGCCTTCTTTGAGGGGACCTCTGAGACGGCAGAGCAATA
CATCAAATCAGCATTGAAACTGTTAATGAAAGGGTAG

Domains

Predicted by InterProScan.

RuvA N terminal domain (RuvA_N)

(1-61)

Helix-hairpin-helix domain (HHH_5)

(71-127)

RuvA, C-terminal domain (RuvA_C)

(152-196)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0DF49

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ruvA Streptococcus pneumoniae TIGR4

65.99

99.495

0.657
  ruvA Streptococcus pneumoniae R6

65.99

99.495

0.657
  ruvA Streptococcus pneumoniae D39

65.99

99.495

0.657
  ruvA Bacillus subtilis subsp. subtilis str. 168

40.887

100

0.419

Multiple sequence alignment