Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   GE024_RS08155 Genome accession   NZ_CP046521
Coordinates   1629336..1629977 (-) Length   213 a.a.
NCBI ID   WP_003044709.1    Uniprot ID   A0A2D4DP75
Organism   Streptococcus canis strain HL_100     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1624336..1634977
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GE024_RS08130 (GE024_08170) - 1624930..1625562 (+) 633 WP_093999506.1 YigZ family protein -
  GE024_RS08135 (GE024_08175) cysK 1625680..1626615 (+) 936 WP_003044700.1 cysteine synthase A -
  GE024_RS08140 (GE024_08180) tnpA 1626888..1627352 (-) 465 Protein_1550 IS200/IS605 family transposase -
  GE024_RS08145 (GE024_08185) - 1627540..1627899 (-) 360 WP_093998981.1 S1 RNA-binding domain-containing protein -
  GE024_RS08150 (GE024_08190) - 1627899..1629299 (-) 1401 WP_093998980.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  GE024_RS08155 (GE024_08195) vraR 1629336..1629977 (-) 642 WP_003044709.1 response regulator transcription factor Regulator
  GE024_RS08160 (GE024_08200) - 1629970..1630974 (-) 1005 WP_003044712.1 sensor histidine kinase -
  GE024_RS08165 (GE024_08205) liaF 1630971..1631663 (-) 693 WP_093998979.1 cell wall-active antibiotics response protein LiaF -
  GE024_RS08170 (GE024_08210) pknB 1631790..1633685 (-) 1896 WP_093998978.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  GE024_RS08175 (GE024_08215) - 1633682..1634422 (-) 741 WP_003044720.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23810.42 Da        Isoelectric Point: 4.8940

>NTDB_id=352612 GE024_RS08155 WP_003044709.1 1629336..1629977(-) (vraR) [Streptococcus canis strain HL_100]
MRKISVILVDDHEMVRMGLKSFLNLQADIDVIGEASNGREGVDLALTLKPDVLVMDLVMPELGGVEATLEILDKWKDAKV
LVLTSYLDNEKIYPVIDAGAKGYMLKTSSAAEILNAIRKVSKGELAIETEVDKKIKAHDQHPDLHEELTAREYDILHLLA
KGYDNQTIADELFISLKTVKTHVSNILAKLEVDDRTQAVVYAFRHHLVPQDDN

Nucleotide


Download         Length: 642 bp        

>NTDB_id=352612 GE024_RS08155 WP_003044709.1 1629336..1629977(-) (vraR) [Streptococcus canis strain HL_100]
ATGCGTAAAATAAGTGTAATTTTAGTGGATGATCATGAAATGGTTCGCATGGGACTCAAAAGTTTTTTGAATTTACAGGC
TGATATTGATGTGATCGGTGAAGCTTCCAATGGGCGTGAAGGGGTCGATTTGGCCTTGACTTTGAAACCAGATGTGTTGG
TGATGGACTTGGTGATGCCAGAGTTAGGTGGTGTAGAAGCGACCTTGGAAATTCTTGACAAGTGGAAAGATGCCAAGGTA
CTGGTTTTAACCTCCTACTTAGATAATGAAAAAATTTACCCTGTCATTGATGCAGGTGCCAAGGGGTATATGTTAAAAAC
ATCGAGTGCAGCTGAAATTTTAAATGCCATTCGCAAGGTTTCAAAGGGAGAACTAGCCATTGAAACAGAGGTTGACAAAA
AAATTAAGGCGCATGATCAACACCCTGACTTGCACGAGGAGTTAACCGCGCGTGAGTATGATATTTTACACCTTTTAGCT
AAAGGGTATGATAATCAGACCATCGCTGATGAACTCTTTATTTCCTTAAAAACCGTCAAAACCCATGTGTCCAATATCCT
AGCCAAGTTAGAAGTTGATGATCGAACCCAAGCAGTTGTCTATGCTTTTCGACACCATTTAGTCCCCCAAGACGATAATT
AA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(6-118)

Bacterial regulatory proteins, luxR family (GerE)

(148-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2D4DP75

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

51.942

96.714

0.502
  degU Bacillus subtilis subsp. subtilis str. 168

35.398

100

0.376

Multiple sequence alignment