Detailed information    

insolico Bioinformatically predicted

Overview

Name   recA   Type   Machinery gene
Locus tag   ES300_RS08905 Genome accession   NZ_CP038251
Coordinates   1749845..1751011 (-) Length   388 a.a.
NCBI ID   WP_001085462.1    Uniprot ID   A0A0B7KZM2
Organism   Streptococcus pneumoniae strain TVO_1901944     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 1742888..1766157 1749845..1751011 within 0


Gene organization within MGE regions


Location: 1742888..1766157
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ES300_RS08860 (ES300_09325) - 1742888..1743148 (-) 261 WP_001209196.1 hypothetical protein -
  ES300_RS08865 (ES300_09330) - 1743207..1743758 (-) 552 WP_001111264.1 hypothetical protein -
  ES300_RS08870 (ES300_09340) - 1743748..1744738 (-) 991 Protein_1763 hypothetical protein -
  ES300_RS08875 (ES300_09345) - 1745146..1745571 (-) 426 WP_000204060.1 hypothetical protein -
  ES300_RS08880 (ES300_09350) - 1745705..1746058 (-) 354 WP_001829107.1 ImmA/IrrE family metallo-endopeptidase -
  ES300_RS08885 (ES300_09355) - 1746104..1746310 (-) 207 WP_000366087.1 hypothetical protein -
  ES300_RS08890 (ES300_09360) - 1746297..1746458 (-) 162 WP_000289348.1 helix-turn-helix domain-containing protein -
  ES300_RS08895 (ES300_09365) lytA 1746836..1747792 (-) 957 WP_000405240.1 N-acetylmuramoyl-L-alanine amidase LytA -
  ES300_RS08900 (ES300_09370) - 1748168..1749538 (-) 1371 WP_001036285.1 MATE family efflux transporter -
  ES300_RS08905 (ES300_09380) recA 1749845..1751011 (-) 1167 WP_001085462.1 recombinase RecA Machinery gene
  ES300_RS08910 (ES300_09385) cinA 1751066..1752322 (-) 1257 WP_000642709.1 competence/damage-inducible protein A Machinery gene
  ES300_RS08915 (ES300_09390) brpA 1752407..1753423 (-) 1017 WP_000239278.1 biofilm formation/cell division transcriptional regulator BrpA -
  ES300_RS08920 (ES300_09395) - 1753431..1753949 (-) 519 WP_000455535.1 GNAT family N-acetyltransferase -
  ES300_RS08925 (ES300_09400) tsaE 1753939..1754382 (-) 444 WP_000288232.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  ES300_RS08930 (ES300_09405) comM 1754468..1755088 (-) 621 WP_000839908.1 hypothetical protein Regulator
  ES300_RS08935 (ES300_09415) - 1755471..1756334 (-) 864 WP_001093618.1 helix-turn-helix domain-containing protein -
  ES300_RS10690 (ES300_09420) - 1756526..1756696 (+) 171 WP_001227862.1 PhrA family quorum-sensing system peptide -
  ES300_RS08940 (ES300_09425) pneA1 1756799..1757023 (+) 225 WP_000181086.1 two-peptide bacteriocin subunit PneA1 -
  ES300_RS08945 (ES300_09430) pneA2 1757030..1757218 (+) 189 WP_000786759.1 two-peptide bacteriocin subunit PneA2 -
  ES300_RS08950 (ES300_09435) - 1757335..1760325 (+) 2991 WP_000875571.1 type 2 lanthipeptide synthetase LanM family protein -
  ES300_RS08955 (ES300_09440) - 1760675..1761379 (+) 705 WP_001033170.1 flavodoxin family protein -
  ES300_RS08960 (ES300_09445) - 1761360..1762289 (+) 930 WP_000912954.1 M50 family metallopeptidase -
  ES300_RS08965 (ES300_09450) - 1762286..1764394 (+) 2109 WP_000701298.1 peptidase domain-containing ABC transporter -
  ES300_RS08970 (ES300_09455) - 1764418..1766157 (+) 1740 WP_054381205.1 S8 family serine peptidase -

Sequence

Protein


Download         Length: 388 a.a.        Molecular weight: 41949.78 Da        Isoelectric Point: 4.8403

>NTDB_id=352564 ES300_RS08905 WP_001085462.1 1749845..1751011(-) (recA) [Streptococcus pneumoniae strain TVO_1901944]
MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGERAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGP
ESSGKTTVALHAVAQAQKEGGIAAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGNPETTPGGRALKFYASVRLDVRG
NTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAVVEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSE
NAKKYLAEHPEIFDEIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVPLDLGDELEIEIEE

Nucleotide


Download         Length: 1167 bp        

>NTDB_id=352564 ES300_RS08905 WP_001085462.1 1749845..1751011(-) (recA) [Streptococcus pneumoniae strain TVO_1901944]
ATGGCGAAAAAACCAAAAAAATTAGAAGAAATTTCAAAAAAATTTGGGGCAGAACGTGAAAAGGCCTTGAATGACGCTCT
TAAATTGATTGAGAAAGACTTTGGTAAAGGATCAATCATGCGTTTGGGTGAACGTGCGGAGCAAAAGGTGCAAGTGATGA
GCTCAGGTTCTTTAGCTCTTGACATTGCCCTTGGCTCAGGTGGTTATCCTAAGGGACGTATCATCGAAATCTATGGCCCA
GAGTCATCTGGTAAGACAACGGTTGCCCTTCATGCAGTTGCACAAGCGCAAAAAGAAGGTGGGATTGCTGCCTTTATCGA
TGCGGAACATGCCCTTGATCCAGCTTATGCTGCGGCCCTTGGTGTCAATATTGACGAATTGCTCTTGTCTCAACCAGACT
CAGGAGAGCAAGGTCTTGAGATTGCGGGAAAATTGATTGACTCAGGTGCAGTTGATCTTGTCGTAGTCGACTCAGTTGCT
GCCCTTGTTCCTCGTGCGGAAATTGATGGAGATATCGGAGATAGCCATGTTGGTTTGCAGGCTCGTATGATGAGCCAGGC
CATGCGTAAACTTGGCGCCTCTATCAATAAAACCAAAACAATTGCCATTTTTATCAACCAATTGCGTGAAAAAGTTGGAG
TGATGTTTGGAAATCCAGAAACAACACCGGGCGGACGTGCTTTGAAATTCTATGCTTCAGTCCGCTTGGATGTTCGTGGT
AATACACAAATTAAGGGAACTGGTGACCAAAAAGAAACCAATGTCGGTAAAGAAACTAAGATTAAGGTTGTAAAAAATAA
GGTAGCTCCACCGTTTAAGGAAGCCGTAGTTGAAATTATGTACGGAGAAGGAATTTCTAAGACTGGTGAGCTTTTGAAGA
TTGCAAGCGATTTGGATATTATCAAAAAAGCAGGGGCTTGGTATTCTTACAAAGATGAAAAAATTGGGCAAGGTTCTGAG
AATGCTAAGAAATACTTGGCAGAGCACCCAGAAATCTTTGATGAAATTGATAAGCAAGTCCGTTCTAAATTTGGCTTGAT
TGATGGAGAAGAAGTTTCAGAACAAGATACTGAAAACAAAAAAGATGAGCCAAAGAAAGAAGAAGCAGTGAATGAAGAAG
TTCCGCTTGACTTAGGCGATGAACTTGAAATCGAAATTGAAGAATAA

Domains

Predicted by InterproScan.

recA bacterial DNA recombination protein (RecA)

(21-286)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7KZM2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  recA Streptococcus pneumoniae Rx1

100

100

1
  recA Streptococcus pneumoniae D39

100

100

1
  recA Streptococcus pneumoniae R6

100

100

1
  recA Streptococcus pneumoniae TIGR4

100

100

1
  recA Streptococcus mitis NCTC 12261

94.072

100

0.941
  recA Streptococcus mitis SK321

93.557

100

0.936
  recA Streptococcus mutans UA159

83.204

99.742

0.83
  recA Streptococcus pyogenes NZ131

90.725

88.918

0.807
  recA Lactococcus lactis subsp. cremoris KW2

78.409

90.722

0.711
  recA Latilactobacillus sakei subsp. sakei 23K

67.919

89.175

0.606
  recA Bacillus subtilis subsp. subtilis str. 168

68.788

85.052

0.585
  recA Glaesserella parasuis strain SC1401

57.641

96.134

0.554
  recA Deinococcus radiodurans R1 = ATCC 13939 = DSM 20539

64.706

83.247

0.539
  recA Neisseria gonorrhoeae MS11

60.177

87.371

0.526
  recA Neisseria gonorrhoeae strain FA1090

60.177

87.371

0.526
  recA Neisseria gonorrhoeae MS11

60.177

87.371

0.526
  recA Vibrio cholerae strain A1552

62.848

83.247

0.523
  recA Vibrio cholerae O1 biovar El Tor strain E7946

62.848

83.247

0.523
  recA Acinetobacter baumannii D1279779

61.963

84.021

0.521
  recA Riemerella anatipestifer ATCC 11845 = DSM 15868

60.725

85.309

0.518
  recA Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.824

87.629

0.515
  recA Acinetobacter baylyi ADP1

61.35

84.021

0.515
  recA Helicobacter pylori 26695

56.125

90.464

0.508
  recA Helicobacter pylori strain NCTC11637

56.125

90.464

0.508
  recA Pseudomonas stutzeri DSM 10701

59.509

84.021

0.5
  recA Ralstonia pseudosolanacearum GMI1000

59.937

81.701

0.49

Multiple sequence alignment