Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB   Type   Machinery gene
Locus tag   E4J95_RS07610 Genome accession   NZ_CP038229
Coordinates   1587571..1588641 (-) Length   356 a.a.
NCBI ID   WP_045176802.1    Uniprot ID   -
Organism   Staphylococcus aureus strain MJ163     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1582571..1593641
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E4J95_RS07570 (E4J95_07925) gcvPA 1582748..1584094 (-) 1347 WP_045177127.1 aminomethyl-transferring glycine dehydrogenase subunit GcvPA -
  E4J95_RS07575 (E4J95_07930) gcvT 1584114..1585205 (-) 1092 WP_000093349.1 glycine cleavage system aminomethyltransferase GcvT -
  E4J95_RS07580 (E4J95_07935) - 1585364..1585888 (-) 525 WP_001015121.1 shikimate kinase -
  E4J95_RS07585 (E4J95_07940) - 1585878..1586024 (-) 147 WP_001789879.1 hypothetical protein -
  E4J95_RS07590 (E4J95_07945) comGF 1586121..1586618 (-) 498 WP_001789864.1 competence type IV pilus minor pilin ComGF Machinery gene
  E4J95_RS07595 (E4J95_07950) comGE 1586536..1586835 (-) 300 WP_000844413.1 hypothetical protein Machinery gene
  E4J95_RS07600 (E4J95_07955) comGD 1586822..1587268 (-) 447 WP_001790850.1 competence type IV pilus minor pilin ComGD Machinery gene
  E4J95_RS07605 (E4J95_07960) comGC 1587246..1587557 (-) 312 WP_000472256.1 competence type IV pilus major pilin ComGC Machinery gene
  E4J95_RS07610 (E4J95_07965) comGB 1587571..1588641 (-) 1071 WP_045176802.1 competence type IV pilus assembly protein ComGB Machinery gene
  E4J95_RS07615 (E4J95_07970) comGA 1588613..1589587 (-) 975 WP_000697227.1 competence type IV pilus ATPase ComGA Machinery gene
  E4J95_RS07620 (E4J95_07975) - 1589639..1590262 (-) 624 WP_001223008.1 MBL fold metallo-hydrolase -
  E4J95_RS07625 (E4J95_07980) - 1590259..1590588 (-) 330 WP_001018871.1 MTH1187 family thiamine-binding protein -
  E4J95_RS07630 (E4J95_07985) - 1590588..1591574 (-) 987 WP_000161314.1 ROK family glucokinase -
  E4J95_RS07635 (E4J95_07990) - 1591571..1591774 (-) 204 WP_000087561.1 YqgQ family protein -
  E4J95_RS07640 (E4J95_07995) - 1591755..1593218 (-) 1464 WP_169449281.1 rhomboid family intramembrane serine protease -

Sequence

Protein


Download         Length: 356 a.a.        Molecular weight: 41456.85 Da        Isoelectric Point: 10.0606

>NTDB_id=352443 E4J95_RS07610 WP_045176802.1 1587571..1588641(-) (comGB) [Staphylococcus aureus strain MJ163]
MKLQWINTFKLHSKKRQLSKAQQIDLLSNLCNLLKYGFTLYQSFQFLNLQMTYKNKQLGTTILSEISNGAPCNQILSLIG
YSDTIVMQVYLAERFGNIIDVLEETVNYMKVNRKSEQRLLKTLQYPLILVSIFIAMIIILNLTVIPQFQQLYTSMNIQLS
SFQKTLSFFITSLPTIIVVMLIIVSMLAIIMKLIYNNLNMLNKINFVMKLPLISGYFQLFKTYFVTNELVLFYKNGITLQ
SIVDVYINHSSDPFRQFLGKYLLTYSEMGYGLPHILEKLKCFKPQLIKFVLQGEKRGKLEVELKLYSQILVKQIEDKAIK
QTQFLQPILFLILGLFIVAIYLVIMLPMFQMMQSIK

Nucleotide


Download         Length: 1071 bp        

>NTDB_id=352443 E4J95_RS07610 WP_045176802.1 1587571..1588641(-) (comGB) [Staphylococcus aureus strain MJ163]
GTGAAACTACAATGGATAAATACATTTAAACTACATTCTAAGAAGCGACAATTAAGTAAGGCCCAACAAATCGACTTACT
TTCAAATTTATGTAATTTGTTGAAATATGGTTTCACTCTGTATCAAAGTTTTCAATTTTTAAATCTTCAAATGACATATA
AAAATAAGCAATTAGGTACCACCATTCTAAGTGAAATTTCAAATGGTGCACCATGCAATCAAATATTATCACTGATAGGT
TATAGCGATACTATCGTCATGCAAGTATATTTGGCAGAAAGATTTGGCAATATTATAGACGTTCTAGAAGAAACCGTAAA
TTATATGAAAGTGAATAGAAAGTCAGAACAACGATTGTTAAAGACACTGCAATATCCCTTAATACTAGTTTCTATCTTTA
TTGCTATGATTATTATATTAAACCTCACAGTAATTCCACAGTTTCAACAATTATATACTTCTATGAATATTCAACTATCT
TCTTTTCAAAAAACATTGTCTTTTTTCATTACCAGCTTACCTACTATAATTGTAGTAATGCTCATAATAGTATCTATGTT
GGCTATTATTATGAAATTAATTTATAACAATTTAAATATGCTCAATAAGATAAACTTTGTGATGAAACTACCGCTAATAT
CAGGCTATTTCCAATTATTTAAAACTTATTTTGTAACTAATGAATTAGTGTTGTTTTATAAAAATGGTATTACACTTCAA
TCAATAGTAGACGTTTATATTAACCATAGTAGTGATCCATTTAGACAGTTTCTAGGTAAATACTTATTAACTTATTCAGA
AATGGGATATGGTTTGCCTCATATTTTAGAAAAACTAAAATGCTTTAAGCCTCAATTAATTAAGTTTGTGCTACAAGGTG
AAAAGAGAGGGAAGCTAGAAGTAGAACTAAAGTTATATTCGCAAATATTAGTAAAACAAATAGAAGATAAAGCGATAAAA
CAGACTCAGTTTTTACAGCCTATTTTATTTTTGATTTTAGGTTTATTTATTGTCGCAATTTATTTAGTAATTATGTTACC
AATGTTTCAAATGATGCAAAGTATAAAATAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(27-146)

Type II secretion system (T2SS), protein F (T2SSF)

(227-347)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB Staphylococcus aureus MW2

99.719

100

0.997
  comGB Staphylococcus aureus N315

99.719

100

0.997

Multiple sequence alignment