Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   GL187_RS10175 Genome accession   NZ_CP046379
Coordinates   1977499..1977993 (-) Length   164 a.a.
NCBI ID   WP_224757748.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 563     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1972499..1982993
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GL187_RS10145 (GL187_10270) - 1972808..1973683 (+) 876 WP_000669493.1 substrate-binding domain-containing protein -
  GL187_RS10150 (GL187_10275) pstC 1973801..1974664 (+) 864 WP_000165892.1 phosphate ABC transporter permease subunit PstC -
  GL187_RS10155 (GL187_10280) pstA 1974657..1975472 (+) 816 WP_000049768.1 phosphate ABC transporter permease PstA -
  GL187_RS10160 (GL187_10285) pstB 1975474..1976226 (+) 753 WP_000536449.1 phosphate ABC transporter ATP-binding protein PstB -
  GL187_RS10165 (GL187_10290) phoU 1976241..1976891 (+) 651 WP_001245781.1 phosphate signaling complex protein PhoU -
  GL187_RS10170 (GL187_10295) - 1976932..1977384 (+) 453 Protein_1985 transposase -
  GL187_RS10175 (GL187_10300) comR 1977499..1977993 (-) 495 WP_224757748.1 helix-turn-helix domain-containing protein Regulator
  GL187_RS10180 (GL187_10305) - 1978151..1979167 (+) 1017 WP_000415103.1 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase -
  GL187_RS10185 (GL187_10310) galU 1979189..1980088 (+) 900 WP_024477964.1 UTP--glucose-1-phosphate uridylyltransferase GalU -
  GL187_RS10190 (GL187_10315) - 1980155..1980832 (-) 678 WP_000658498.1 rhomboid family intramembrane serine protease -
  GL187_RS10195 (GL187_10320) - 1980816..1981355 (-) 540 WP_024477965.1 5-formyltetrahydrofolate cyclo-ligase -
  GL187_RS10200 (GL187_10325) - 1981367..1982497 (-) 1131 WP_000885066.1 N-acetyldiaminopimelate deacetylase -

Sequence

Protein


Download         Length: 164 a.a.        Molecular weight: 19750.82 Da        Isoelectric Point: 4.8839

>NTDB_id=351524 GL187_RS10175 WP_224757748.1 1977499..1977993(-) (comR) [Streptococcus pneumoniae strain 563]
MIQYMLIIEVNNSGGSCRLREFGEKIKRLRLAKKISRSEFCGDESELSIRQLIRIENGESRPILTKLKYIAERLEVEDYK
LMPSYIELDKEYLELKYFLMRTPTYEDETIAQKKESVFDKIFEEYYDRLPEEERFIIPNYSYLALTNYTVQKLPEKLVEI
LSFW

Nucleotide


Download         Length: 495 bp        

>NTDB_id=351524 GL187_RS10175 WP_224757748.1 1977499..1977993(-) (comR) [Streptococcus pneumoniae strain 563]
TTGATTCAGTATATGCTTATAATAGAGGTAAACAACTCAGGAGGTTCTTGTAGGTTGCGAGAGTTTGGCGAAAAAATTAA
AAGATTACGTTTGGCTAAAAAAATCAGTCGTTCAGAATTTTGTGGTGATGAGTCTGAATTAAGTATCCGTCAATTAATTA
GAATTGAAAATGGAGAATCCAGACCAATACTAACAAAGTTAAAATATATTGCTGAACGTTTGGAGGTTGAAGATTACAAG
TTGATGCCAAGTTATATAGAGTTGGATAAGGAATACCTAGAATTGAAGTATTTCTTGATGAGGACTCCTACATACGAAGA
TGAAACTATCGCCCAAAAGAAAGAGAGTGTTTTTGATAAGATTTTTGAAGAGTATTATGATAGGCTACCTGAGGAAGAAA
GATTTATCATCCCAAATTATTCATATCTGGCACTAACGAACTACACAGTTCAAAAATTACCAGAAAAGCTAGTTGAAATA
CTGTCCTTCTGGTGA

Domains

Predicted by InterProScan.

ComR tetratricopeptide (ComR_TPR)

(90-137)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus pyogenes MGAS8232

55.833

73.171

0.409
  comR Streptococcus pyogenes MGAS315

54.167

73.171

0.396
  comR Streptococcus mutans UA159

52.5

73.171

0.384