Detailed information NTG0351509

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: GL187_RS09540
• Genome accession: NZ_CP046379
• Coordinates: 1871673..1872572 (-)
• Length: 299 a.a.
• NCBI ID: WP_024477664.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 563
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1866673..1877572

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GL187_RS09515 (GL187_09630)	rsmA	1866898..1867770 (-)	873	WP_001216852.1	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA	-
GL187_RS09520 (GL187_09635)	-	1868021..1868314 (-)	294	WP_000333255.1	hypothetical protein	-
GL187_RS09525 (GL187_09640)	-	1868307..1868948 (-)	642	WP_000565531.1	ABC transporter ATP-binding protein	-
GL187_RS09530 (GL187_09645)	-	1868950..1870980 (-)	2031	WP_024477663.1	bacteriocin-associated integral membrane family protein	-
GL187_RS09535 (GL187_09650)	-	1871057..1871353 (-)	297	WP_000815392.1	lactococcin 972 family bacteriocin	-
GL187_RS09540 (GL187_09655)	comR	1871673..1872572 (-)	900	WP_024477664.1	helix-turn-helix transcriptional regulator	Regulator
GL187_RS09545 (GL187_09660)	rnmV	1872644..1873204 (-)	561	WP_024477665.1	ribonuclease M5	-
GL187_RS09550 (GL187_09665)	-	1873204..1873977 (-)	774	WP_024477666.1	TatD family hydrolase	-
GL187_RS09555 (GL187_09670)	-	1874282..1875001 (-)	720	Protein_1890	DUF1542 domain-containing protein	-
GL187_RS09560 (GL187_09675)	rpmH	1875210..1875344 (-)	135	WP_000831905.1	50S ribosomal protein L34	-
GL187_RS09565 (GL187_09680)	-	1875524..1876477 (-)	954	WP_001155339.1	IS30-like element ISSpn8 family transposase	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35337.14 Da
• Isoelectric Point: 4.9064

>NTDB_id=351509 GL187_RS09540 WP_024477664.1 1871673..1872572(-) (comR) [Streptococcus pneumoniae strain 563]
MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPSLPKLDYIARRLGVPVYSLMPDFSALPPAYLELKYQI
LREPIYGKEEEYDKKEACLEEIYKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMSQIIEKEVYSTNDMLL
IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTKLENFFIIRDTLISGMCCLEKVGVTDCFNDYLSCLQEIMDKTQDY
QKKPLVFMFLWKQALREERDFSLAESFYQSSKTFAKLIGDGFLVKKLTEEWQEDVKKYL

Nucleotide

• Length: 900 bp

>NTDB_id=351509 GL187_RS09540 WP_024477664.1 1871673..1872572(-) (comR) [Streptococcus pneumoniae strain 563]
ATGTTAATTGGTCAAAAAATTAAAGAGATTCGGATAGAAAAAGGAATTAGTCGTCCAGATTTTTGTGGAGATGAGCAAGA
ACTGACAGTTCGTCAACTGTCGCGAATTGAAAGTGGAGCTTCGCAACCGAGTTTGCCCAAGTTAGACTATATTGCTCGCC
GGCTAGGAGTTCCAGTTTATAGCCTTATGCCGGATTTTTCAGCTCTTCCTCCTGCTTATTTAGAATTGAAATACCAGATT
TTACGTGAACCAATCTATGGTAAAGAAGAGGAGTACGATAAGAAGGAAGCGTGTTTGGAAGAGATTTATAAAACATACTT
TGATAATCTTCCTAAAGAAGAACAATTAGCATGTGAAGTATTGCAGGCGTGTTTGGATACTTCTAGAACTAGAAGGCCTG
AATATGCAGAGTTAATACTTGAGGAACATATGTCTCAGATCATAGAAAAAGAAGTTTATTCAACAAATGATATGTTGTTG
ATTCGTTTGTTTTTTTATCAAATGCTCATTAGAAAAGATCTTGCCAAATTTATAAATCAAATCGAAAAGCTAATGCTCTT
TCTTTTGGAACAGAAAAAGGTAACTAAATTAGAAAACTTCTTTATAATTAGAGATACTCTTATTTCAGGAATGTGTTGTC
TTGAAAAGGTAGGAGTAACTGATTGTTTTAATGATTATCTATCGTGTTTACAAGAAATTATGGATAAAACTCAAGATTAT
CAAAAGAAACCTCTTGTATTTATGTTTTTGTGGAAGCAAGCATTAAGAGAAGAAAGAGATTTTAGTTTAGCTGAATCATT
TTATCAGTCTTCTAAAACATTTGCGAAGCTAATTGGAGATGGATTTCTAGTAAAGAAATTGACAGAGGAATGGCAAGAGG
ATGTCAAAAAATATTTATAA

Domains

Predicted by InterProScan.

• ComR tetratricopeptide (ComR_TPR) (70-291)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus suis P1/7	37.801	97.324	0.368
comR	Streptococcus suis 05ZYH33	37.801	97.324	0.368
comR	Streptococcus mutans UA159	37.415	98.328	0.368
comR	Streptococcus pyogenes MGAS8232	36.242	99.666	0.361