Detailed information NTG0351272

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: GL188_RS09425
• Genome accession: NZ_CP046359
• Coordinates: 1852849..1853748 (-)
• Length: 299 a.a.
• NCBI ID: WP_024477664.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 573
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1847849..1858748

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GL188_RS09400 (GL188_09555)	rsmA	1848074..1848946 (-)	873	WP_001216852.1	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA	-
GL188_RS09405 (GL188_09560)	-	1849197..1849490 (-)	294	WP_000333255.1	hypothetical protein	-
GL188_RS09410 (GL188_09565)	-	1849483..1850124 (-)	642	WP_000565531.1	ABC transporter ATP-binding protein	-
GL188_RS09415 (GL188_09570)	-	1850126..1852156 (-)	2031	WP_024477663.1	bacteriocin-associated integral membrane family protein	-
GL188_RS09420 (GL188_09575)	-	1852233..1852529 (-)	297	WP_000815392.1	lactococcin 972 family bacteriocin	-
GL188_RS09425 (GL188_09580)	comR	1852849..1853748 (-)	900	WP_024477664.1	helix-turn-helix transcriptional regulator	Regulator
GL188_RS09430 (GL188_09585)	rnmV	1853820..1854380 (-)	561	WP_024477665.1	ribonuclease M5	-
GL188_RS09435 (GL188_09590)	-	1854380..1855153 (-)	774	WP_024477666.1	TatD family hydrolase	-
GL188_RS09440 (GL188_09595)	-	1855458..1856177 (-)	720	Protein_1868	DUF1542 domain-containing protein	-
GL188_RS09445 (GL188_09600)	rpmH	1856386..1856520 (-)	135	WP_000831905.1	50S ribosomal protein L34	-
GL188_RS09450 (GL188_09605)	-	1856665..1857879 (-)	1215	WP_000666469.1	pyridoxal phosphate-dependent aminotransferase	-
GL188_RS09455 (GL188_09610)	-	1858035..1858328 (-)	294	WP_000977366.1	hypothetical protein	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35337.14 Da
• Isoelectric Point: 4.9064

>NTDB_id=351272 GL188_RS09425 WP_024477664.1 1852849..1853748(-) (comR) [Streptococcus pneumoniae strain 573]
MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPSLPKLDYIARRLGVPVYSLMPDFSALPPAYLELKYQI
LREPIYGKEEEYDKKEACLEEIYKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMSQIIEKEVYSTNDMLL
IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTKLENFFIIRDTLISGMCCLEKVGVTDCFNDYLSCLQEIMDKTQDY
QKKPLVFMFLWKQALREERDFSLAESFYQSSKTFAKLIGDGFLVKKLTEEWQEDVKKYL

Nucleotide

• Length: 900 bp

>NTDB_id=351272 GL188_RS09425 WP_024477664.1 1852849..1853748(-) (comR) [Streptococcus pneumoniae strain 573]
ATGTTAATTGGTCAAAAAATTAAAGAGATTCGGATAGAAAAAGGAATTAGTCGTCCAGATTTTTGTGGAGATGAGCAAGA
ACTGACAGTTCGTCAACTGTCGCGAATTGAAAGTGGAGCTTCGCAACCGAGTTTGCCCAAGTTAGACTATATTGCTCGCC
GGCTAGGAGTTCCAGTTTATAGCCTTATGCCGGATTTTTCAGCTCTTCCTCCTGCTTATTTAGAATTGAAATACCAGATT
TTACGTGAACCAATCTATGGTAAAGAAGAGGAGTACGATAAGAAGGAAGCGTGTTTGGAAGAGATTTATAAAACATACTT
TGATAATCTTCCTAAAGAAGAACAATTAGCATGTGAAGTATTGCAGGCGTGTTTGGATACTTCTAGAACTAGAAGGCCTG
AATATGCAGAGTTAATACTTGAGGAACATATGTCTCAGATCATAGAAAAAGAAGTTTATTCAACAAATGATATGTTGTTG
ATTCGTTTGTTTTTTTATCAAATGCTCATTAGAAAAGATCTTGCCAAATTTATAAATCAAATCGAAAAGCTAATGCTCTT
TCTTTTGGAACAGAAAAAGGTAACTAAATTAGAAAACTTCTTTATAATTAGAGATACTCTTATTTCAGGAATGTGTTGTC
TTGAAAAGGTAGGAGTAACTGATTGTTTTAATGATTATCTATCGTGTTTACAAGAAATTATGGATAAAACTCAAGATTAT
CAAAAGAAACCTCTTGTATTTATGTTTTTGTGGAAGCAAGCATTAAGAGAAGAAAGAGATTTTAGTTTAGCTGAATCATT
TTATCAGTCTTCTAAAACATTTGCGAAGCTAATTGGAGATGGATTTCTAGTAAAGAAATTGACAGAGGAATGGCAAGAGG
ATGTCAAAAAATATTTATAA

Domains

Predicted by InterProScan.

• ComR tetratricopeptide (ComR_TPR) (70-291)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus suis P1/7	37.801	97.324	0.368
comR	Streptococcus suis 05ZYH33	37.801	97.324	0.368
comR	Streptococcus mutans UA159	37.415	98.328	0.368
comR	Streptococcus pyogenes MGAS8232	36.242	99.666	0.361