Detailed information NTG0351150

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: GL186_RS09485
• Genome accession: NZ_CP046358
• Coordinates: 1857246..1858145 (-)
• Length: 299 a.a.
• NCBI ID: WP_024477664.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 566
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1852246..1863145

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GL186_RS09460 (GL186_09625)	rsmA	1852471..1853343 (-)	873	WP_001216852.1	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA	-
GL186_RS09465 (GL186_09630)	-	1853594..1853887 (-)	294	WP_000333255.1	hypothetical protein	-
GL186_RS09470 (GL186_09635)	-	1853880..1854521 (-)	642	WP_000565531.1	ABC transporter ATP-binding protein	-
GL186_RS09475 (GL186_09640)	-	1854523..1856553 (-)	2031	WP_024477663.1	bacteriocin-associated integral membrane family protein	-
GL186_RS09480 (GL186_09645)	-	1856630..1856926 (-)	297	WP_000815392.1	lactococcin 972 family bacteriocin	-
GL186_RS09485 (GL186_09650)	comR	1857246..1858145 (-)	900	WP_024477664.1	helix-turn-helix transcriptional regulator	Regulator
GL186_RS09490 (GL186_09655)	rnmV	1858217..1858777 (-)	561	WP_024477665.1	ribonuclease M5	-
GL186_RS09495 (GL186_09660)	-	1858777..1859550 (-)	774	WP_024477666.1	TatD family hydrolase	-
GL186_RS09500 (GL186_09665)	-	1859855..1860574 (-)	720	Protein_1879	DUF1542 domain-containing protein	-
GL186_RS09505 (GL186_09670)	rpmH	1860783..1860917 (-)	135	WP_000831905.1	50S ribosomal protein L34	-
GL186_RS09510 (GL186_09675)	-	1861062..1862276 (-)	1215	WP_000666469.1	pyridoxal phosphate-dependent aminotransferase	-
GL186_RS09515 (GL186_09680)	-	1862432..1862725 (-)	294	WP_000977366.1	hypothetical protein	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35337.14 Da
• Isoelectric Point: 4.9064

>NTDB_id=351150 GL186_RS09485 WP_024477664.1 1857246..1858145(-) (comR) [Streptococcus pneumoniae strain 566]
MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPSLPKLDYIARRLGVPVYSLMPDFSALPPAYLELKYQI
LREPIYGKEEEYDKKEACLEEIYKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMSQIIEKEVYSTNDMLL
IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTKLENFFIIRDTLISGMCCLEKVGVTDCFNDYLSCLQEIMDKTQDY
QKKPLVFMFLWKQALREERDFSLAESFYQSSKTFAKLIGDGFLVKKLTEEWQEDVKKYL

Nucleotide

• Length: 900 bp

>NTDB_id=351150 GL186_RS09485 WP_024477664.1 1857246..1858145(-) (comR) [Streptococcus pneumoniae strain 566]
ATGTTAATTGGTCAAAAAATTAAAGAGATTCGGATAGAAAAAGGAATTAGTCGTCCAGATTTTTGTGGAGATGAGCAAGA
ACTGACAGTTCGTCAACTGTCGCGAATTGAAAGTGGAGCTTCGCAACCGAGTTTGCCCAAGTTAGACTATATTGCTCGCC
GGCTAGGAGTTCCAGTTTATAGCCTTATGCCGGATTTTTCAGCTCTTCCTCCTGCTTATTTAGAATTGAAATACCAGATT
TTACGTGAACCAATCTATGGTAAAGAAGAGGAGTACGATAAGAAGGAAGCGTGTTTGGAAGAGATTTATAAAACATACTT
TGATAATCTTCCTAAAGAAGAACAATTAGCATGTGAAGTATTGCAGGCGTGTTTGGATACTTCTAGAACTAGAAGGCCTG
AATATGCAGAGTTAATACTTGAGGAACATATGTCTCAGATCATAGAAAAAGAAGTTTATTCAACAAATGATATGTTGTTG
ATTCGTTTGTTTTTTTATCAAATGCTCATTAGAAAAGATCTTGCCAAATTTATAAATCAAATCGAAAAGCTAATGCTCTT
TCTTTTGGAACAGAAAAAGGTAACTAAATTAGAAAACTTCTTTATAATTAGAGATACTCTTATTTCAGGAATGTGTTGTC
TTGAAAAGGTAGGAGTAACTGATTGTTTTAATGATTATCTATCGTGTTTACAAGAAATTATGGATAAAACTCAAGATTAT
CAAAAGAAACCTCTTGTATTTATGTTTTTGTGGAAGCAAGCATTAAGAGAAGAAAGAGATTTTAGTTTAGCTGAATCATT
TTATCAGTCTTCTAAAACATTTGCGAAGCTAATTGGAGATGGATTTCTAGTAAAGAAATTGACAGAGGAATGGCAAGAGG
ATGTCAAAAAATATTTATAA

Domains

Predicted by InterProScan.

• ComR tetratricopeptide (ComR_TPR) (70-291)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus suis P1/7	37.801	97.324	0.368
comR	Streptococcus suis 05ZYH33	37.801	97.324	0.368
comR	Streptococcus mutans UA159	37.415	98.328	0.368
comR	Streptococcus pyogenes MGAS8232	36.242	99.666	0.361