Detailed information NTG0350952

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: E2H98_RS18160
• Genome accession: NZ_CP037953
• Coordinates: 4023656..4025026 (-)
• Length: 456 a.a.
• NCBI ID: WP_133587123.1
• Uniprot ID: A0A4R6UVL8
• Organism: Permianibacter aggregans strain HW001
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 4018656..4030026

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E2H98_RS18145 (E2H98_18090)	-	4019609..4021651 (+)	2043	WP_232475432.1	carboxy terminal-processing peptidase	-
E2H98_RS18150 (E2H98_18095)	-	4021761..4022552 (+)	792	WP_133587119.1	Crp/Fnr family transcriptional regulator	-
E2H98_RS18155 (E2H98_18100)	thiO	4022558..4023643 (+)	1086	WP_133587121.1	glycine oxidase ThiO	-
E2H98_RS18160 (E2H98_18105)	pilR	4023656..4025026 (-)	1371	WP_133587123.1	sigma-54 dependent transcriptional regulator	Regulator
E2H98_RS18165 (E2H98_18110)	-	4025023..4026660 (-)	1638	WP_133587125.1	PAS domain-containing sensor histidine kinase	-
E2H98_RS18170 (E2H98_18115)	-	4026870..4028480 (+)	1611	WP_133587127.1	NAD+ synthase	-
E2H98_RS18175 (E2H98_18120)	glnB	4028529..4028867 (+)	339	WP_133587129.1	nitrogen regulatory protein P-II	-

Sequence

Protein

• Length: 456 a.a.
• Molecular weight: 50233.12 Da
• Isoelectric Point: 6.2019

>NTDB_id=350952 E2H98_RS18160 WP_133587123.1 4023656..4025026(-) (pilR) [Permianibacter aggregans strain HW001]
MKNPLALIVDDEPDILELLSITLGRMRVDTKEAATLQEARQLLEDTPFDMCLTDLRLPDGDGIELVKHIQQVKPNLPVAV
ITAHGNMQTAIEAMKAGAFDFLSKPIDLNTLRDLVKNALHLQPPAPTTKESDIPTGSPRLIGSSSRMSALRQTIAKVSRS
QAPIHITGESGTGKELVARLIHALGPRKEGPFVPVNCGAIPGELMESEFFGHKKGSFTGAIADKPGLFQTADGGTLFLDE
VADLPLTMQVKLLRAIQERAVRPVGASKEIAVNVRIVSATHKDLAELVNAGQFRQDLFYRINVISVTTPSLRDRIEDIPE
LAQYILKKLSERHHVDEPKLTASAINGLKKYAFPGNIRELENILERALTLADGHEIEIEDLQLPDSPMEVVDPAALAMIT
PGKRGDIPLDMYLEKIERDAVLEALEFCRWNKTQAARKLGISFRAMRYKLQKLGLE

Nucleotide

• Length: 1371 bp

>NTDB_id=350952 E2H98_RS18160 WP_133587123.1 4023656..4025026(-) (pilR) [Permianibacter aggregans strain HW001]
ATGAAAAACCCGTTAGCGCTGATCGTCGATGACGAACCGGATATTCTCGAACTGCTGTCCATCACGCTAGGCCGCATGCG
CGTCGACACCAAAGAAGCGGCAACGCTGCAAGAAGCGCGACAACTGCTGGAAGACACGCCGTTCGATATGTGTCTGACTG
ATCTGCGCCTGCCAGATGGCGATGGCATCGAATTGGTCAAACATATCCAGCAAGTCAAACCGAATCTGCCGGTCGCCGTG
ATCACCGCACATGGCAATATGCAGACCGCCATTGAGGCGATGAAGGCAGGCGCTTTTGACTTTCTGTCGAAACCCATCGA
TTTGAACACGCTGCGCGATCTGGTCAAGAACGCGCTGCATCTGCAACCGCCGGCACCGACCACTAAAGAAAGTGATATTC
CAACCGGTTCGCCACGTCTGATTGGTTCCAGCAGCCGCATGTCGGCCTTGCGCCAAACCATCGCCAAAGTGTCGCGCTCG
CAGGCGCCGATCCATATCACCGGCGAATCCGGTACCGGCAAAGAGCTGGTGGCGCGTTTGATCCACGCCTTGGGTCCACG
CAAAGAAGGACCATTTGTACCGGTCAATTGCGGCGCCATTCCCGGCGAGTTGATGGAAAGCGAGTTTTTCGGCCACAAGA
AAGGCAGCTTTACCGGCGCCATTGCCGACAAACCGGGCTTGTTTCAAACCGCCGATGGCGGCACGCTTTTTCTCGATGAA
GTCGCCGACCTGCCGTTGACGATGCAAGTCAAATTGCTGCGGGCCATTCAGGAGCGTGCGGTACGCCCGGTTGGCGCCAG
CAAGGAAATTGCGGTCAATGTGCGCATCGTCAGTGCTACCCACAAAGATCTGGCCGAGCTGGTCAATGCCGGCCAGTTTC
GTCAGGACTTGTTCTATAGAATCAACGTTATTTCGGTAACAACGCCATCGCTGCGTGATCGCATTGAGGATATTCCGGAA
CTGGCGCAATACATCCTGAAAAAGCTGTCGGAGCGTCATCATGTCGACGAACCGAAACTGACCGCTTCGGCAATCAATGG
CCTGAAAAAATATGCGTTCCCTGGCAACATCCGCGAGCTGGAAAATATTCTCGAGCGGGCGCTGACCTTGGCTGACGGCC
ACGAAATCGAAATTGAGGATTTGCAATTACCGGATAGCCCGATGGAGGTCGTTGATCCGGCGGCACTGGCGATGATCACG
CCAGGTAAACGCGGCGACATTCCGCTCGACATGTATCTGGAAAAAATCGAACGCGATGCGGTGCTGGAAGCCCTGGAATT
TTGTCGATGGAACAAGACCCAGGCAGCCCGCAAGCTCGGCATCAGTTTCCGGGCGATGCGCTATAAATTGCAGAAATTGG
GACTCGAATAA

Domains

Predicted by InterproScan.

• Sigma-54 interaction domain (Sigma54_activat) (140-306)

• Response regulator receiver domain (Response_reg) (7-115)

• Bacterial regulatory protein, Fis family (HTH_8) (413-453)

3D structure

• AlphaFold DB: A0A4R6UVL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	60.613	100	0.607
pilR	Acinetobacter baumannii strain A118	49.462	100	0.504
luxO	Vibrio cholerae strain A1552	38.222	98.684	0.377