Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   GL183_RS03170 Genome accession   NZ_CP046355
Coordinates   595522..596199 (+) Length   225 a.a.
NCBI ID   WP_000548961.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 475     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 590522..601199
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GL183_RS03140 (GL183_03155) - 590892..591538 (-) 647 Protein_571 nicotinamide mononucleotide transporter -
  GL183_RS03145 (GL183_03165) - 591715..592365 (-) 651 WP_000188505.1 metal-dependent transcriptional regulator -
  GL183_RS03150 (GL183_03170) - 592477..593319 (+) 843 WP_000160928.1 metallophosphoesterase family protein -
  GL183_RS03155 (GL183_03175) - 593395..593832 (+) 438 WP_001166786.1 Rrf2 family transcriptional regulator -
  GL183_RS03160 (GL183_03180) - 593900..594202 (+) 303 WP_000281608.1 hypothetical protein -
  GL183_RS03165 (GL183_03185) - 594293..595366 (-) 1074 WP_001273817.1 DUF2974 domain-containing protein -
  GL183_RS03170 (GL183_03190) braR 595522..596199 (+) 678 WP_000548961.1 response regulator transcription factor Regulator
  GL183_RS03175 (GL183_03195) - 596192..597166 (+) 975 WP_000887954.1 HAMP domain-containing histidine kinase -
  GL183_RS03180 (GL183_03200) thrS 597215..599158 (-) 1944 WP_000608358.1 threonine--tRNA ligase -
  GL183_RS03185 (GL183_03205) - 599216..599539 (-) 324 WP_000422781.1 hypothetical protein -
  GL183_RS03190 (GL183_03220) - 599970..600170 (-) 201 WP_001814296.1 hypothetical protein -
  GL183_RS03195 (GL183_03225) - 600407..601036 (+) 630 WP_000762099.1 NAD(P)-dependent oxidoreductase -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 25950.13 Da        Isoelectric Point: 5.1362

>NTDB_id=350752 GL183_RS03170 WP_000548961.1 595522..596199(+) (braR) [Streptococcus pneumoniae strain 475]
MHKILLIEDDQVIRQQVGKMLSEWGFEVVLVEDFMEVLSLFVQSEPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSS
RDQAMDIVMAINMGADDFVTKPFDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGIGYGLKHA

Nucleotide


Download         Length: 678 bp        

>NTDB_id=350752 GL183_RS03170 WP_000548961.1 595522..596199(+) (braR) [Streptococcus pneumoniae strain 475]
ATGCACAAGATTTTATTAATAGAAGATGATCAGGTCATTCGTCAACAGGTCGGGAAAATGCTCTCTGAATGGGGATTTGA
AGTGGTCCTGGTAGAAGACTTTATGGAAGTTTTGAGTCTATTTGTTCAGTCGGAACCTCATCTGGTCCTCATGGATATTG
GTTTGCCCTTGTTTAATGGTTATCACTGGTGTCAGGAAATCCGCAAGATTTCCAAGGTACCTATCATGTTTCTTTCTTCG
AGAGACCAGGCTATGGATATTGTCATGGCAATCAATATGGGGGCGGATGACTTTGTGACCAAGCCTTTTGACCAGCAGGT
TCTTTTAGCTAAGGTTCAGGGCTTGTTGCGTCGTTCCTATGAGTTTGGGCGTGATGAGAGTTTGCTGGAATATGCTGGTG
TTATCCTCAATACCAAATCCATGGATTTACATTATCAAGGGCAAGTCTTGAATTTGACCAAGAATGAATTCCAGATTTTA
CGCGTGTTATTTGAGCATGCAGGCAACATCGTAGCACGTGACGACCTGATGCGGGAACTTTGGAACAGTGACTTTTTCAT
TGATGATAATACCCTCTCTGTCAATGTGGCTCGTTTGCGTAAAAAGTTGGAGGAGCAGGGATTGGTAGGATTTATCGAGA
CCAAGAAAGGAATAGGGTACGGATTGAAGCATGCTTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-221)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

48.624

96.889

0.471
  vicR Streptococcus mutans UA159

34.894

100

0.364

Multiple sequence alignment