Detailed information NTG0350706

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: CKAES1R_RS25035
• Genome accession: NZ_CP037926
• Coordinates: 5202873..5204210 (+)
• Length: 445 a.a.
• NCBI ID: WP_003094694.1
• Uniprot ID: A0A0H2ZG94
• Organism: Pseudomonas aeruginosa strain AES1R
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 5197873..5209210

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CKAES1R_RS25010 (CKAES1R_04922)	pgeF	5198016..5198744 (-)	729	WP_019682292.1	peptidoglycan editing factor PgeF	-
CKAES1R_RS25015 (CKAES1R_04923)	rluD	5198741..5199703 (-)	963	WP_003094686.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
CKAES1R_RS25020 (CKAES1R_04924)	-	5199849..5200874 (+)	1026	WP_003102590.1	outer membrane protein assembly factor BamD	-
CKAES1R_RS25025 (CKAES1R_04925)	-	5201031..5201276 (+)	246	WP_003102591.1	PP0621 family protein	-
CKAES1R_RS25030 (CKAES1R_04926)	pilS	5201266..5202858 (+)	1593	WP_003094692.1	two-component system sensor histidine kinase PilS	Regulator
CKAES1R_RS25035 (CKAES1R_04927)	pilR	5202873..5204210 (+)	1338	WP_003094694.1	two-component system response regulator PilR	Regulator
CKAES1R_RS25040 (CKAES1R_04928)	thiO	5204256..5205350 (-)	1095	WP_023108762.1	glycine oxidase ThiO	-
CKAES1R_RS25045 (CKAES1R_04929)	-	5205485..5205994 (+)	510	WP_017002065.1	Tfp pilus assembly protein FimT/FimU	-
CKAES1R_RS25050 (CKAES1R_04930)	-	5206100..5206606 (+)	507	WP_003102598.1	Tfp pilus assembly protein FimT/FimU	-
CKAES1R_RS25055 (CKAES1R_04931)	pilV	5206597..5207154 (+)	558	WP_003119423.1	type 4a pilus minor pilin PilV	Machinery gene
CKAES1R_RS25060 (CKAES1R_04932)	pilW	5207151..5207975 (+)	825	WP_003119422.1	type 4a pilus minor pilin PilW	-
CKAES1R_RS25065 (CKAES1R_04933)	pilX	5207972..5208559 (+)	588	WP_003112826.1	type 4a pilus minor pilin PilX	-

Sequence

Protein

• Length: 445 a.a.
• Molecular weight: 49737.06 Da
• Isoelectric Point: 5.8654

>NTDB_id=350706 CKAES1R_RS25035 WP_003094694.1 5202873..5204210(+) (pilR) [Pseudomonas aeruginosa strain AES1R]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide

• Length: 1338 bp

>NTDB_id=350706 CKAES1R_RS25035 WP_003094694.1 5202873..5204210(+) (pilR) [Pseudomonas aeruginosa strain AES1R]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGTAGCGGCAAGGAGCTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAACTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCGCCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTACACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCCGCGAGCCTGAGCGAAATAGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCGCTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (7-115)

• Sigma-54 interaction domain (Sigma54_activat) (135-301)

• Bacterial regulatory protein, Fis family (HTH_8) (402-442)

3D structure

• AlphaFold DB: A0A0H2ZG94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	100	100	1
pilR	Acinetobacter baumannii strain A118	51.198	100	0.528
luxO	Vibrio cholerae strain A1552	38.17	100	0.384