Detailed information NTG0034990

Bioinformatically predicted

Overview

• Name: pilC
• Type: Machinery gene
• Locus tag: NMO_RS10875
• Genome accession: NC_013016
• Coordinates: 2111856..2115020 (-)
• Length: 1054 a.a.
• NCBI ID: WP_015815989.1
• Uniprot ID: C6S9L7
• Organism: Neisseria meningitidis alpha14
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2106856..2120020

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NMO_RS10870 (NMO_1959)	yccS	2108360..2110504 (+)	2145	WP_015815988.1	YccS family putative transporter	-
NMO_RS10875 (NMO_1960)	pilC	2111856..2115020 (-)	3165	WP_015815989.1	PilC family type IV pilus tip adhesin	Machinery gene
NMO_RS10880 (NMO_1961)	-	2115865..2116149 (-)	285	WP_002246543.1	GIY-YIG nuclease family protein	-
NMO_RS10885 (NMO_1962)	pilA	2116690..2117955 (-)	1266	WP_002236294.1	signal recognition particle-docking protein FtsY	Machinery gene
NMO_RS10890 (NMO_1963)	msrAB	2118100..2119668 (+)	1569	WP_002216163.1	bifunctional peptide-methionine (S)-S-oxide reductase MsrA/peptide-methionine (R)-S-oxide reductase MsrB	-

Sequence

Protein

• Length: 1054 a.a.
• Molecular weight: 114960.50 Da
• Isoelectric Point: 9.6242

>NTDB_id=34990 NMO_RS10875 WP_015815989.1 2111856..2115020(-) (pilC) [Neisseria meningitidis alpha14]
MNKTWKRQVFRHTALYTAILMFSHTGGGGGQAQAQTQTQTHKYAIVMNAQNLPEVKWGNQYQSLTHKSNEREVIHTSGFG
LAKKYISFSFNNTDEVVAEKKDAVVFGAATYLPPYGKVSGFDTTKLTERKNAVDQIGTTHPGLVGYSYEGSTCSSGSCPT
VAYRTQFTFGNSSLAKKTNGGGLDIYEDKSRDNSPIYKLKDHPWLGVSFNLGGESSFKPKRQGSLVSSFSEDVTQQNGAD
SQHKGKNLVYTTDDYKSQNNKNHQDKHHAVAFYLNAKLHLLDKKHITNIAQVGTVDLGTLKTRIEPTEAWKKQNNNFFSG
SWTYEEKGLVSVKLILPQVKAGRCVNKNNPNPNKKDLSPALTAPALWFGAGQNGKAEMYSASVSTYPDSSSSRIFLQNLK
RKTDHSKPGRHSLATLNKSDIESKEPSFTGRQTVIRLDGGVHEIKLKGNEVEGFKGNNGNATFGIVKDLGVDPDANEWKK
VLLPWTVRASNDDGQFNTFNKEENNGKPKYSQKYRSRDNGKHERNLGDIVNSPIVAVGGYLATSANDGMVHIFKKGNGDD
RNYSLKLSYIPGTMPRKDIESKDSTLAKELRAFAEKGYVGDRYGVDGGFVLRQVEWKGQNRVFMFGAMGFGGRGAYALDL
TKADGNDPTKASLFDVKNNGNNGNNGNNSVKLGYTVGTPQIGKTYNGKYAAFLASGYATKQIDSGENTTALYVYDLEGNG
TNNLIKKIEVSGGKGGLSSPTLVDKDLDGTIDIAYAGDRGGSMYRFDLSGQDPSQWTVRTIFQGTKPITSAPAISQLKDK
RVVIFGTGSDLSEEDVDNMEEQYIYGIFDDDTAATGTVNFTGTGGGLLEQHLTEENKTLFLTDYKRSDGSGSKGWVVKLK
DGQRVTVKPTVVLRTAFVTIRKYNDGGCGAQTAILGINTADGGKLTKKSARPIVPEANTAVAQYSGHKKGTNGKSIPIGC
MQKGNEIVCPNGYVYDKPVNVRYLDEKKTDGFSTTADGDAGGSGIDPDGKRAGKNNRCFSQKGVRTLLMNDLDSLDITGP
TCGMKRISWREVFY

Nucleotide

• Length: 3165 bp

>NTDB_id=34990 NMO_RS10875 WP_015815989.1 2111856..2115020(-) (pilC) [Neisseria meningitidis alpha14]
ATGAATAAAACTTGGAAACGGCAGGTTTTCCGCCATACCGCGCTTTATACCGCCATATTGATGTTTTCCCATACCGGCGG
GGGGGGGGGGCAGGCGCAAGCGCAAACGCAAACGCAAACGCATAAATACGCTATTGTAATGAACGCGCAAAATCTGCCCG
AGGTAAAGTGGGGGAATCAATATCAGTCATTGACGCACAAAAGCAATGAACGCGAAGTTATCCATACGAGTGGTTTTGGT
TTGGCAAAAAAGTACATTAGTTTCTCATTCAATAATACCGATGAAGTTGTTGCTGAAAAAAAAGATGCTGTCGTTTTCGG
CGCGGCGACTTATCTGCCGCCCTACGGCAAGGTTTCCGGTTTTGATACCACTAAGCTGACCGAGCGCAAAAATGCCGTTG
ATCAGATTGGTACGACCCACCCTGGGTTAGTAGGCTACAGCTACGAAGGTAGCACATGCTCCAGCGGAAGTTGTCCTACA
GTTGCCTATAGAACCCAATTTACCTTCGGCAATTCCAGTTTGGCAAAAAAGACAAACGGCGGCGGGCTGGATATATACGA
AGACAAAAGCCGCGACAATTCGCCCATTTACAAATTGAAGGATCATCCTTGGTTGGGCGTGTCTTTCAATTTGGGCGGAG
AGAGCTCCTTCAAACCAAAGAGACAAGGTTCTTTGGTATCTTCTTTTAGCGAGGACGTGACGCAGCAAAATGGTGCGGAC
AGCCAACACAAAGGCAAAAACCTCGTTTATACGACAGACGATTACAAGAGTCAGAATAATAAAAACCATCAGGACAAACA
CCACGCCGTCGCCTTTTATCTGAACGCCAAGCTGCACCTGCTGGATAAAAAACACATCACAAATATCGCGCAAGTCGGAA
CAGTTGATTTGGGTACCTTGAAAACACGCATCGAGCCGACGGAAGCATGGAAAAAACAGAATAATAACTTTTTCAGCGGT
AGTTGGACGTATGAAGAGAAAGGATTAGTCAGCGTCAAACTCATCTTGCCGCAAGTCAAAGCAGGCCGCTGCGTCAACAA
AAATAACCCCAATCCCAACAAAAAAGACCTTTCGCCGGCACTGACTGCCCCCGCGCTGTGGTTCGGAGCTGGGCAAAATG
GTAAGGCGGAGATGTATTCCGCTTCGGTTTCCACCTACCCCGACAGTTCGAGCAGCCGCATCTTCCTTCAAAATCTGAAA
AGAAAAACCGACCACAGCAAACCCGGTCGCCATTCCCTCGCAACCTTGAATAAGTCGGATATTGAAAGTAAAGAGCCGAG
TTTCACAGGGCGGCAAACCGTCATCCGATTGGATGGCGGCGTACATGAGATCAAACTTAAAGGTAATGAGGTCGAAGGTT
TTAAGGGAAACAACGGCAACGCAACTTTCGGCATTGTTAAGGACTTGGGCGTCGATCCTGATGCCAATGAGTGGAAAAAA
GTGCTGCTGCCTTGGACGGTTCGTGCTTCCAATGATGACGGTCAATTTAACACATTCAACAAAGAAGAAAACAACGGCAA
GCCAAAATACAGTCAAAAATACCGCAGCCGCGACAACGGCAAGCACGAGCGCAATTTGGGCGACATCGTCAACAGCCCCA
TCGTGGCGGTCGGCGGGTATTTGGCTACTTCCGCCAACGACGGGATGGTGCATATCTTCAAAAAAGGCAACGGGGATGAC
CGCAACTATAGTCTGAAGCTCAGCTACATCCCCGGCACGATGCCGCGCAAGGATATTGAAAGCAAAGACTCCACCCTTGC
CAAAGAGCTGCGCGCCTTTGCCGAAAAAGGCTATGTGGGCGACCGCTACGGCGTGGACGGCGGCTTTGTCTTGCGCCAAG
TCGAATGGAAAGGGCAAAACCGCGTGTTTATGTTCGGCGCGATGGGCTTTGGCGGCAGAGGCGCATACGCCTTGGATTTG
ACCAAAGCCGACGGCAATGACCCGACAAAAGCCTCTTTGTTTGATGTAAAAAATAACGGCAATAATGGCAATAACGGCAA
TAATAGCGTGAAATTAGGCTACACCGTCGGCACGCCGCAAATCGGCAAAACCTACAACGGCAAATACGCCGCTTTCCTCG
CCTCCGGTTATGCGACTAAACAAATTGACAGCGGCGAGAATACAACCGCGCTGTATGTGTATGATTTGGAAGGAAACGGT
ACGAATAATCTGATTAAAAAAATCGAAGTATCCGGCGGCAAGGGCGGGCTTTCGTCCCCCACGTTGGTGGATAAAGATTT
GGACGGCACGATCGATATCGCCTATGCCGGCGATCGCGGCGGCAGTATGTACCGCTTTGATTTGAGCGGTCAAGATCCTA
GTCAATGGACTGTACGCACTATTTTCCAAGGCACGAAGCCGATTACTTCCGCGCCCGCCATTTCCCAACTGAAAGACAAA
CGCGTGGTTATCTTCGGTACGGGCAGTGATTTGAGTGAAGAGGATGTGGACAATATGGAAGAACAATATATTTACGGTAT
CTTCGACGACGATACAGCGGCGACGGGTACTGTAAACTTCACCGGTACGGGAGGCGGGCTGCTCGAGCAACACCTTACTG
AGGAAAATAAAACCTTATTCCTGACCGATTATAAGCGATCCGACGGCTCGGGCAGCAAAGGGTGGGTAGTGAAATTGAAG
GACGGACAGCGCGTTACCGTCAAACCGACCGTGGTATTGCGTACCGCCTTTGTAACCATCCGCAAATATAACGACGGCGG
CTGCGGCGCGCAAACCGCCATTTTGGGCATCAATACCGCCGACGGCGGCAAGCTGACCAAGAAAAGCGCGCGCCCGATTG
TGCCAGAAGCCAATACGGCTGTCGCGCAATATTCCGGCCATAAGAAAGGCACCAACGGCAAATCCATCCCTATAGGTTGT
ATGCAAAAAGGCAATGAAATCGTCTGCCCGAACGGATATGTTTACGACAAACCGGTTAATGTGCGTTATCTGGATGAAAA
GAAAACAGACGGATTTTCAACAACGGCAGACGGCGATGCGGGCGGCAGCGGTATAGACCCCGACGGCAAGCGTGCCGGCA
AAAACAACCGCTGCTTCTCCCAAAAAGGGGTGCGCACCCTGCTGATGAACGATTTGGACAGCTTGGACATTACCGGCCCG
ACGTGCGGTATGAAACGAATCAGCTGGCGTGAAGTCTTCTACTGA

Domains

Predicted by InterproScan.

• Neisseria PilC beta-propeller domain (T4P_PilY1) (526-862)

3D structure

• AlphaFold DB: C6S9L7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilC	Neisseria meningitidis A1493	74.06	100	0.748