Detailed information NTG0034991

Bioinformatically predicted

Overview

• Name: pilA
• Type: Machinery gene
• Locus tag: NMO_RS10885
• Genome accession: NC_013016
• Coordinates: 2116690..2117955 (-)
• Length: 421 a.a.
• NCBI ID: WP_002236294.1
• Uniprot ID: C6S9L9
• Organism: Neisseria meningitidis alpha14
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2111690..2122955

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NMO_RS10875 (NMO_1960)	pilC	2111856..2115020 (-)	3165	WP_015815989.1	PilC family type IV pilus tip adhesin	Machinery gene
NMO_RS10880 (NMO_1961)	-	2115865..2116149 (-)	285	WP_002246543.1	GIY-YIG nuclease family protein	-
NMO_RS10885 (NMO_1962)	pilA	2116690..2117955 (-)	1266	WP_002236294.1	signal recognition particle-docking protein FtsY	Machinery gene
NMO_RS10890 (NMO_1963)	msrAB	2118100..2119668 (+)	1569	WP_002216163.1	bifunctional peptide-methionine (S)-S-oxide reductase MsrA/peptide-methionine (R)-S-oxide reductase MsrB	-
NMO_RS10895 (NMO_1964)	-	2119770..2120255 (-)	486	WP_002221794.1	CinA family protein	-
NMO_RS10900 (NMO_1965)	-	2120281..2121129 (-)	849	WP_002215243.1	mechanosensitive ion channel family protein	-
NMO_RS10905 (NMO_1966)	-	2121223..2122224 (-)	1002	WP_002220087.1	thiamine ABC transporter substrate-binding protein	-

Sequence

Protein

• Length: 421 a.a.
• Molecular weight: 45184.43 Da
• Isoelectric Point: 4.5589

>NTDB_id=34991 NMO_RS10885 WP_002236294.1 2116690..2117955(-) (pilA) [Neisseria meningitidis alpha14]
MFSFFRRKKKQETPALEEAQIQETAAKAESETDQVIENIKEDAESLAESVKGQVESAVETVSGAVEQVKETVAEMLSEAE
EAAEKAAEQVEAAKEAIAETVGEAVGQVQEAVATTEEHKLGWAARLKQGLTKSRDKMAKSLAGVFGGGQIDEDLYEELET
VLITSDMGMEATEYLMKDVRDRVSLKGLKDGNELRGALKDALYDLIKPLEKPLVLPETKEPFVIMLAGINGAGKTTSIGK
LAKYFQAHGKSVLLAAGDTFRAAAREQLQAWGERNNVTVISQTTGDSAAVCFDAVQAAKARGIDIVLADTAGRLPTQLHL
MEEIKKVKRVLQKAMPDAPHEIIVVLDANIGQNAVNQVKAFDDALGLTGLIVTKLDGTAKGGILAALASDRPVPVRYIGV
GEGIDDLRPFDARAFVDALLD

Nucleotide

• Length: 1266 bp

>NTDB_id=34991 NMO_RS10885 WP_002236294.1 2116690..2117955(-) (pilA) [Neisseria meningitidis alpha14]
ATGTTCAGCTTCTTCCGTCGCAAGAAAAAACAGGAAACGCCGGCTCTCGAGGAGGCTCAAATTCAGGAAACCGCAGCAAA
AGCAGAGTCCGAAACCGATCAAGTAATTGAAAATATTAAAGAAGATGCTGAATCTTTAGCAGAAAGCGTCAAAGGGCAGG
TCGAATCTGCCGTTGAAACCGTCAGCGGTGCGGTTGAACAGGTAAAGGAAACCGTTGCCGAGATGCTGTCTGAAGCAGAG
GAAGCGGCGGAAAAAGCAGCGGAACAAGTCGAAGCGGCAAAAGAAGCCATTGCCGAAACCGTCGGCGAGGCTGTCGGGCA
AGTTCAAGAAGCCGTTGCGACAACTGAAGAACACAAGCTCGGTTGGGCGGCGCGTTTGAAACAAGGCCTGACCAAATCGC
GCGACAAAATGGCGAAATCGCTGGCGGGCGTGTTCGGCGGCGGACAAATCGACGAAGATTTGTACGAAGAGCTGGAAACC
GTGCTGATTACCAGCGACATGGGCATGGAAGCCACCGAATACCTGATGAAAGACGTGCGCGACCGCGTCAGCCTCAAAGG
GCTGAAAGACGGCAACGAATTGCGCGGCGCGCTGAAAGATGCGCTGTACGACCTGATTAAGCCTCTGGAGAAACCTTTGG
TCTTGCCCGAAACCAAAGAGCCTTTCGTGATTATGCTTGCAGGTATCAACGGCGCGGGCAAAACCACGTCTATCGGCAAA
CTCGCCAAATATTTCCAAGCGCATGGAAAATCCGTATTGCTGGCGGCAGGCGATACTTTCCGTGCCGCCGCGCGTGAGCA
GCTTCAAGCTTGGGGCGAACGCAACAACGTAACCGTGATTTCGCAAACCACGGGCGATTCCGCCGCCGTGTGCTTCGATG
CCGTCCAAGCCGCCAAAGCGCGCGGCATCGACATTGTGCTGGCCGACACCGCCGGCCGCCTGCCCACGCAGCTTCACTTG
ATGGAAGAAATCAAAAAAGTGAAACGCGTGCTGCAAAAAGCCATGCCCGACGCGCCACACGAAATCATCGTCGTGCTTGA
TGCCAATATCGGTCAAAACGCCGTCAACCAAGTCAAAGCCTTTGACGACGCATTGGGGCTGACCGGTTTAATTGTTACCA
AGCTAGACGGCACGGCAAAAGGCGGCATCCTCGCCGCGCTTGCCTCCGACCGCCCCGTCCCCGTCCGCTATATCGGCGTG
GGCGAAGGCATAGACGATTTGCGCCCGTTTGACGCGCGCGCGTTTGTGGACGCACTGCTGGATTGA

Domains

Predicted by InterproScan.

• SRP54-type protein, GTPase domain (SRP54) (221-420)

• SRP54-type protein, helical bundle domain (SRP54_N) (136-202)

3D structure

• AlphaFold DB: C6S9L9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilA	Neisseria gonorrhoeae MS11	93.349	100	0.933