Detailed information NTG0349458

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: EZ612_RS02225
• Genome accession: NZ_CP036531
• Coordinates: 417634..418635 (+)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain STAB10048
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 412634..423635

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EZ612_RS02200 (EZ612_02235)	-	413308..413991 (-)	684	WP_031488436.1	DUF969 domain-containing protein	-
EZ612_RS02205 (EZ612_02240)	-	414202..415128 (-)	927	WP_002994177.1	glycosyltransferase family 2 protein	-
EZ612_RS02210 (EZ612_02245)	-	415273..415650 (-)	378	WP_002985686.1	VOC family protein	-
EZ612_RS02215 (EZ612_02250)	-	415661..416326 (-)	666	WP_031488435.1	NAD(P)H-dependent oxidoreductase	-
EZ612_RS02220 (EZ612_02255)	-	416375..417460 (-)	1086	WP_031488434.1	aminopeptidase P family protein	-
EZ612_RS02225 (EZ612_02260)	ccpA	417634..418635 (+)	1002	WP_002985680.1	catabolite control protein A	Regulator
EZ612_RS02230 (EZ612_02265)	-	418766..419764 (+)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
EZ612_RS02235 (EZ612_02270)	-	419766..421100 (+)	1335	WP_011284590.1	glycosyltransferase family 4 protein	-
EZ612_RS02240 (EZ612_02275)	thrS	421522..423465 (+)	1944	WP_002985672.1	threonine--tRNA ligase	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=349458 EZ612_RS02225 WP_002985680.1 417634..418635(+) (ccpA) [Streptococcus pyogenes strain STAB10048]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=349458 EZ612_RS02225 WP_002985680.1 417634..418635(+) (ccpA) [Streptococcus pyogenes strain STAB10048]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAATTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGGTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACTAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559