Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   GJD95_RS03585 Genome accession   NZ_CP046006
Coordinates   423381..424013 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 1919D3     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 418381..429013
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GJD95_RS03560 (GJD95_03560) yhfG 418513..418680 (+) 168 WP_000736862.1 YhfG family protein -
  GJD95_RS03565 (GJD95_03565) fic 418670..419272 (+) 603 WP_001280641.1 putative adenosine monophosphate-protein transferase Fic -
  GJD95_RS03570 (GJD95_03570) pabA 419304..419867 (+) 564 WP_097433417.1 aminodeoxychorismate synthase component 2 -
  GJD95_RS03575 (GJD95_03575) argD 419953..421173 (+) 1221 WP_000963796.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  GJD95_RS03580 (GJD95_03580) yhfK 421240..423330 (-) 2091 WP_001345983.1 YccS/YhfK family putative transporter -
  GJD95_RS03585 (GJD95_03585) crp 423381..424013 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  GJD95_RS03590 (GJD95_03590) yhfA 424315..424719 (+) 405 WP_001148908.1 OsmC family protein -
  GJD95_RS03595 (GJD95_03595) prkB 424774..425643 (-) 870 WP_001274680.1 phosphoribulokinase -
  GJD95_RS03600 (GJD95_03600) yheU 425697..425915 (-) 219 WP_000907085.1 YheU family protein -
  GJD95_RS03605 (GJD95_03605) yheT 425909..426931 (-) 1023 WP_000057356.1 hydrolase -
  GJD95_RS03610 (GJD95_03610) yheS 426931..428844 (-) 1914 WP_000634793.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=349430 GJD95_RS03585 WP_000242755.1 423381..424013(-) (crp) [Escherichia coli strain 1919D3]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=349430 GJD95_RS03585 WP_000242755.1 423381..424013(-) (crp) [Escherichia coli strain 1919D3]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment