Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   GJE16_RS01865 Genome accession   NZ_CP045931
Coordinates   353212..353844 (+) Length   210 a.a.
NCBI ID   WP_000698401.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain AUSMDU00010538     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 348212..358844
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GJE16_RS01840 (GJE16_01840) mvaD 348490..349443 (+) 954 WP_000373457.1 diphosphomevalonate decarboxylase -
  GJE16_RS01845 (GJE16_01845) - 349430..350437 (+) 1008 WP_047474505.1 phosphomevalonate kinase -
  GJE16_RS01850 (GJE16_01850) fni 350421..351431 (+) 1011 WP_000210618.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  GJE16_RS01855 (GJE16_01855) liaF 351508..352206 (+) 699 WP_001224640.1 cell wall-active antibiotics response protein LiaF -
  GJE16_RS01860 (GJE16_01860) - 352203..353198 (+) 996 WP_000743669.1 sensor histidine kinase -
  GJE16_RS01865 (GJE16_01865) vraR 353212..353844 (+) 633 WP_000698401.1 response regulator transcription factor Regulator
  GJE16_RS11215 (GJE16_01870) - 353845..354086 (+) 242 Protein_366 DNA alkylation repair protein -
  GJE16_RS10925 - 354068..354613 (+) 546 Protein_367 DNA alkylation repair protein -
  GJE16_RS01885 (GJE16_01885) - 354763..355002 (+) 240 WP_000754501.1 hypothetical protein -
  GJE16_RS01890 (GJE16_01890) cbpG 355083..355673 (+) 591 Protein_369 choline-binding protein CbpG -
  GJE16_RS01895 (GJE16_01895) - 356029..356334 (+) 306 WP_000889974.1 tyrosine-type recombinase/integrase -
  GJE16_RS01900 (GJE16_01900) tig 356528..357811 (+) 1284 WP_000116465.1 trigger factor -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23518.03 Da        Isoelectric Point: 4.7164

>NTDB_id=348793 GJE16_RS01865 WP_000698401.1 353212..353844(+) (vraR) [Streptococcus pneumoniae strain AUSMDU00010538]
MKILLVDDHEMVRLGLKSYFDLQADVEVVGEASNGSQGIDLALELRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIV
TSYLDNEKIMPVLDAGAKGYMLKTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGHEEF

Nucleotide


Download         Length: 633 bp        

>NTDB_id=348793 GJE16_RS01865 WP_000698401.1 353212..353844(+) (vraR) [Streptococcus pneumoniae strain AUSMDU00010538]
ATGAAAATTTTACTAGTAGATGACCATGAAATGGTCCGATTGGGCTTGAAAAGCTACTTTGACCTCCAAGCCGATGTAGA
AGTTGTGGGTGAGGCGTCCAACGGGTCTCAAGGGATTGACTTGGCCTTGGAACTGCGTCCGGATGTTATTGTTATGGATA
TTGTCATGCCTGAGATGAATGGGATTGATGCGACCTTGGCTATCCTCAAAGAATGGCCTGAAGCCAAGATTTTGATTGTG
ACCTCTTATTTGGACAATGAAAAAATCATGCCAGTCTTAGATGCTGGTGCCAAAGGCTATATGCTCAAGACTTCTAGTGC
AGATGAATTGCTTCATGCCGTCAGTAAGGTAGCTGCTGGCGAGCTGGCCATTGAGCAAGAGGTTAGCAAGAAGGTTGAAT
ACCACCGCAATCATATGGAACTTCATGAAGAATTGACTGCGCGTGAGCGAGATGTTCTCCAACTCATCGCCAAGGGCTAC
GAAAATCAGCGCATCGCAGATGACCTCTTTATCTCTCTCAAGACGGTCAAGACCCACGTGTCCAACATTCTTGCCAAACT
TGAAGTCAGCGATCGTACCCAGGCGGCTGTCTACGCCTTTCAGCACCATTTGGTGGGGCATGAGGAGTTTTAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-114)

Bacterial regulatory proteins, luxR family (GerE)

(145-199)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.153

99.524

0.519
  degU Bacillus subtilis subsp. subtilis str. 168

38.393

100

0.41

Multiple sequence alignment