Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB2   Type   Machinery gene
Locus tag   EYC28_RS06985 Genome accession   NZ_CP036380
Coordinates   1467851..1468132 (-) Length   93 a.a.
NCBI ID   WP_001272686.1    Uniprot ID   G2MDJ3
Organism   Helicobacter pylori strain 125C7     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1462851..1473132
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EYC28_RS06965 - 1463562..1464902 (-) 1341 WP_001987737.1 COG3014 family protein -
  EYC28_RS06975 comB4 1465223..1467586 (-) 2364 WP_000890500.1 VirB4 family type IV secretion/conjugal transfer ATPase Machinery gene
  EYC28_RS06980 comB3 1467588..1467851 (-) 264 WP_000584955.1 hypothetical protein Machinery gene
  EYC28_RS06985 comB2 1467851..1468132 (-) 282 WP_001272686.1 TrbC/VirB2 family protein Machinery gene
  EYC28_RS06990 - 1468277..1469104 (-) 828 WP_001154973.1 DUF5718 family protein -
  EYC28_RS06995 - 1469195..1470247 (-) 1053 WP_000802576.1 MnmA/TRMU family protein -
  EYC28_RS07000 dnaG 1470244..1471923 (-) 1680 WP_000601614.1 DNA primase -
  EYC28_RS07005 groES 1472196..1472552 (+) 357 WP_000671954.1 co-chaperone GroES -

Sequence

Protein


Download         Length: 93 a.a.        Molecular weight: 10539.81 Da        Isoelectric Point: 9.1450

>NTDB_id=348390 EYC28_RS06985 WP_001272686.1 1467851..1468132(-) (comB2) [Helicobacter pylori strain 125C7]
MSAHFLKIIFLVGMCVSSLFAEGLEGFFNALEAQLKSPIAKGILMVIFIGIAIYVWRNLDRWKEILFTILGVVFGIFLFF
KAPSLANWFMGIF

Nucleotide


Download         Length: 282 bp        

>NTDB_id=348390 EYC28_RS06985 WP_001272686.1 1467851..1468132(-) (comB2) [Helicobacter pylori strain 125C7]
ATGTCCGCTCATTTTTTAAAAATCATTTTTTTAGTAGGCATGTGCGTTTCAAGTTTGTTCGCTGAAGGATTAGAAGGGTT
TTTTAACGCCCTAGAAGCCCAGCTCAAAAGCCCCATCGCTAAGGGAATTTTAATGGTGATTTTCATAGGGATCGCTATTT
ATGTGTGGAGGAATTTAGACCGGTGGAAAGAGATTTTATTCACGATCCTTGGCGTGGTGTTTGGGATTTTTTTATTCTTT
AAAGCCCCGAGTTTAGCGAATTGGTTCATGGGAATTTTTTAA

Domains

Predicted by InterproScan.

TrbC/VIRB2 pilin (TrbC)

(6-89)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G2MDJ3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB2 Helicobacter pylori 26695

98.925

100

0.989

Multiple sequence alignment