Detailed information NTG0346444

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: GII88_RS00615
• Genome accession: NZ_CP045814
• Coordinates: 113360..114436 (+)
• Length: 358 a.a.
• NCBI ID: WP_003178277.1
• Uniprot ID: Q65PD4
• Organism: Bacillus licheniformis strain P8_B2
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 108360..119436

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GII88_RS00600 (GII88_00600)	-	108377..109468 (+)	1092	WP_003178273.1	protein arginine kinase	-
GII88_RS00605 (GII88_00605)	clpC	109465..111897 (+)	2433	WP_003178275.1	ATP-dependent protease ATP-binding subunit ClpC	Regulator
GII88_RS00610 (GII88_00610)	radA/sms	111977..113356 (+)	1380	WP_003178276.1	DNA repair protein RadA	Machinery gene
GII88_RS00615 (GII88_00615)	disA	113360..114436 (+)	1077	WP_003178277.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
GII88_RS00620 (GII88_00620)	-	114568..115656 (+)	1089	WP_003178278.1	PIN/TRAM domain-containing protein	-
GII88_RS00625 (GII88_00625)	ispD	115673..116368 (+)	696	WP_003178279.1	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-
GII88_RS00630 (GII88_00630)	ispF	116361..116837 (+)	477	WP_003178280.1	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	-
GII88_RS00635 (GII88_00635)	gltX	116919..118376 (+)	1458	WP_003178281.1	glutamate--tRNA ligase	-
GII88_RS00640 (GII88_00640)	cysE	118678..119328 (+)	651	WP_003178282.1	serine O-acetyltransferase	-

Sequence

Protein

• Length: 358 a.a.
• Molecular weight: 40582.27 Da
• Isoelectric Point: 6.5986

>NTDB_id=346444 GII88_RS00615 WP_003178277.1 113360..114436(+) (disA) [Bacillus licheniformis strain P8_B2]
MDKDKKGAKQDLSEILQFVAPGTPLREGIENVLRAKTGGLIVVGFNDKVKEVVDGGFHINSSFSPAHLYELAKMDGAIIL
SDSGQKILYANTQLMPEATIPSSETGMRHRTAERVAKQTGCLIIAISERRNVITLYQENMKYILKDIGFILTKANQAIQT
LEKYKLILDHAISNLNALEFEELVTFGDVISVLHRYEMVLRIKNEINMYIKELGTEGHLIRLQVSELITDMEQEAALFVK
DYVKEKIKDPFVLLKQLQDMSSFELLDDAILLKLLGYSATTNMEEYVFPRGYRLLHKIPRLPMPIVENVVEAFGHLKLII
EADVKDLDEVEGIGAVRAQKIKKGLKRLQEKHYTDRQL

Nucleotide

• Length: 1077 bp

>NTDB_id=346444 GII88_RS00615 WP_003178277.1 113360..114436(+) (disA) [Bacillus licheniformis strain P8_B2]
ATGGACAAAGACAAAAAAGGAGCGAAACAGGATCTTTCAGAAATATTGCAGTTTGTCGCCCCCGGCACGCCTCTTCGCGA
AGGAATCGAAAACGTCCTTCGGGCCAAAACAGGCGGATTAATCGTGGTCGGCTTCAACGATAAAGTGAAAGAAGTGGTTG
ACGGAGGGTTCCACATAAATTCTTCTTTCTCTCCGGCTCATCTGTACGAGCTGGCTAAAATGGACGGGGCGATCATTCTC
AGCGATTCAGGGCAAAAAATTCTATATGCCAATACACAGCTCATGCCTGAGGCGACGATTCCCTCCTCTGAGACGGGCAT
GAGACACAGAACAGCCGAGCGTGTGGCCAAGCAGACCGGCTGTCTGATCATCGCGATTTCTGAAAGACGGAATGTGATTA
CGCTCTATCAGGAAAATATGAAATATATACTCAAAGATATCGGCTTTATCTTAACAAAAGCCAATCAGGCGATTCAGACG
CTCGAAAAATACAAACTCATTTTGGACCATGCGATTTCCAATTTGAACGCGCTGGAATTTGAAGAGCTTGTTACATTTGG
GGATGTCATCTCCGTTCTGCATCGATATGAAATGGTGCTCAGAATCAAAAACGAAATTAATATGTATATTAAAGAGCTTG
GAACAGAAGGCCATCTCATCAGACTCCAGGTTAGCGAACTGATCACCGATATGGAGCAGGAAGCGGCGCTGTTCGTCAAA
GATTATGTGAAAGAAAAAATCAAAGACCCGTTTGTTCTGCTGAAACAGCTTCAGGATATGTCGAGTTTCGAATTGCTGGA
TGATGCGATTCTCCTTAAGCTTTTAGGCTATTCAGCAACTACGAACATGGAAGAATACGTTTTTCCGAGAGGCTACAGGC
TTCTCCACAAAATTCCCCGCCTCCCGATGCCGATCGTCGAAAATGTTGTCGAAGCATTCGGCCATTTAAAGCTCATTATC
GAAGCGGATGTAAAAGATTTGGATGAAGTGGAAGGAATTGGGGCTGTTCGTGCCCAAAAGATAAAGAAAGGGTTAAAGAG
ACTTCAGGAGAAACATTATACTGACAGGCAGCTGTGA

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (27-139)

• DisA bacterial checkpoint controller linker region (DisA-linker) (144-282)

3D structure

• AlphaFold DB: Q65PD4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	86.111	100	0.866