Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   GFB63_RS01235 Genome accession   NZ_CP045596
Coordinates   257291..257935 (-) Length   214 a.a.
NCBI ID   WP_002951384.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain TK-P3A     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 252291..262935
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GFB63_RS01210 (GFB63_01265) - 254395..255393 (-) 999 WP_111679664.1 NAD(P)/FAD-dependent oxidoreductase -
  GFB63_RS01215 (GFB63_01270) trmD 255395..256114 (-) 720 WP_011226285.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  GFB63_RS01220 (GFB63_01275) rimM 256104..256622 (-) 519 WP_011681402.1 ribosome maturation factor RimM -
  GFB63_RS01235 (GFB63_01290) vraR 257291..257935 (-) 645 WP_002951384.1 response regulator transcription factor Regulator
  GFB63_RS01240 (GFB63_01295) - 257925..258935 (-) 1011 WP_100262586.1 sensor histidine kinase -
  GFB63_RS01245 (GFB63_01300) liaF 258932..259630 (-) 699 WP_014621793.1 cell wall-active antibiotics response protein LiaF -
  GFB63_RS10400 - 259885..260052 (-) 168 WP_228024402.1 potassium channel family protein -
  GFB63_RS01255 (GFB63_01310) stkP/pknB 260687..262558 (-) 1872 WP_084826071.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24048.39 Da        Isoelectric Point: 4.5864

>NTDB_id=345172 GFB63_RS01235 WP_002951384.1 257291..257935(-) (vraR) [Streptococcus thermophilus strain TK-P3A]
MSNKINVILVDDHEMVRLGLKSFLNLQGDVEVVGEAENGREGVDLALELRPDVVVMDLVMPELDGVQATLELLKEWPEAK
ILVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNSIRKVYRGEEAIETEVDNKIKYHDSHPNLHDDLTARERDILALL
AKGYDNQTIANELFISLKTVKTHVSNILGKLNVDDRTQAVVYAFRHHLVSQDDE

Nucleotide


Download         Length: 645 bp        

>NTDB_id=345172 GFB63_RS01235 WP_002951384.1 257291..257935(-) (vraR) [Streptococcus thermophilus strain TK-P3A]
ATGTCGAATAAGATTAATGTAATTTTGGTAGATGACCATGAAATGGTTCGTTTAGGCCTTAAGAGTTTCTTGAATCTCCA
AGGAGATGTAGAAGTGGTTGGAGAGGCAGAAAACGGCCGTGAGGGTGTCGATCTTGCCCTGGAGCTACGACCAGATGTCG
TTGTTATGGACCTTGTTATGCCTGAGCTAGATGGTGTTCAGGCGACTTTGGAATTGCTCAAAGAATGGCCTGAAGCTAAG
ATTCTAGTTTTGACCAGCTATTTGGATAATGAAAAAATTTATCCAGTCATTGAAGCTGGCGCCAAAGGCTATATGCTTAA
AACGAGCAGTGCAGCAGAGATTCTAAATAGTATCCGTAAGGTTTACCGTGGAGAGGAAGCTATCGAAACTGAGGTAGACA
ATAAGATTAAATACCACGATAGTCACCCGAACTTACATGATGACTTGACCGCGCGCGAACGTGATATCTTAGCCCTCCTA
GCTAAAGGCTATGACAATCAAACCATTGCTAACGAACTTTTTATTTCTTTAAAAACCGTCAAGACTCATGTGTCTAATAT
CCTTGGGAAATTAAATGTTGATGACCGTACTCAGGCTGTAGTTTATGCCTTTAGACATCATCTGGTTTCACAGGATGATG
AATAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(7-118)

Bacterial regulatory proteins, luxR family (GerE)

(149-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

50.485

96.262

0.486
  degU Bacillus subtilis subsp. subtilis str. 168

36.161

100

0.379

Multiple sequence alignment