Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   GC231_RS24235 Genome accession   NZ_CP045213
Coordinates   4959734..4960324 (-) Length   196 a.a.
NCBI ID   WP_065225231.1    Uniprot ID   -
Organism   Escherichia coli strain EH41     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4954734..4965324
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GC231_RS24220 (GC231_24425) uhpT 4955374..4956765 (-) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -
  GC231_RS24225 (GC231_24430) uhpC 4956903..4958222 (-) 1320 WP_001296914.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  GC231_RS24230 (GC231_24435) uhpB 4958232..4959734 (-) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  GC231_RS24235 (GC231_24440) letA 4959734..4960324 (-) 591 WP_065225231.1 transcriptional regulator UhpA Regulator
  GC231_RS24240 (GC231_24445) ilvN 4960399..4960689 (-) 291 WP_001181706.1 acetolactate synthase small subunit -
  GC231_RS24245 (GC231_24450) ilvB 4960693..4962381 (-) 1689 WP_000168480.1 acetolactate synthase large subunit -
  GC231_RS24250 (GC231_24455) ivbL 4962487..4962585 (-) 99 WP_001315912.1 ilvB operon leader peptide IvbL -
  GC231_RS24255 (GC231_24460) tisB 4963150..4963239 (+) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  GC231_RS24260 ysdE 4963502..4963576 (-) 75 WP_211180519.1 protein YsdE -
  GC231_RS24265 (GC231_24465) emrD 4963658..4964842 (+) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20847.22 Da        Isoelectric Point: 5.9982

>NTDB_id=344052 GC231_RS24235 WP_065225231.1 4959734..4960324(-) (letA) [Escherichia coli strain EH41]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTGHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=344052 GC231_RS24235 WP_065225231.1 4959734..4960324(-) (letA) [Escherichia coli strain EH41]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAACTGCTAAGCCAGCTGCCGAAAGGTATGGCGACAATAATGCTCTCTGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTCTCCAAACGCTGTAGCCCTGACGA
ACTGATTGCGGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGCGAACGGCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCTGCC
GAACTGGGCTTGTCGCCGAAAACGGGGCACGTCCATCGCGCCAACCTGATGGAAAAACTGGGTGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Bacterial regulatory proteins, luxR family (GerE)

(136-191)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

32.735

100

0.372