Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   GC226_RS23420 Genome accession   NZ_CP045209
Coordinates   4827144..4827734 (-) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain 4     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4822144..4832734
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GC226_RS23405 (GC226_23620) uhpT 4822784..4824175 (-) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -
  GC226_RS23410 (GC226_23625) uhpC 4824313..4825632 (-) 1320 WP_001296914.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  GC226_RS23415 (GC226_23630) uhpB 4825642..4827144 (-) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  GC226_RS23420 (GC226_23635) letA 4827144..4827734 (-) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  GC226_RS23425 (GC226_23640) ilvN 4827809..4828099 (-) 291 WP_001181706.1 acetolactate synthase small subunit -
  GC226_RS23430 (GC226_23645) ilvB 4828103..4829791 (-) 1689 WP_000168480.1 acetolactate synthase large subunit -
  GC226_RS23435 (GC226_23650) ivbL 4829897..4829995 (-) 99 WP_001315912.1 ilvB operon leader peptide IvbL -
  GC226_RS23440 (GC226_23655) tisB 4830560..4830649 (+) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  GC226_RS23445 ysdE 4830912..4830986 (-) 75 WP_211180519.1 protein YsdE -
  GC226_RS23450 (GC226_23660) emrD 4831068..4832252 (+) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=343971 GC226_RS23420 WP_000633668.1 4827144..4827734(-) (letA) [Escherichia coli strain 4]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=343971 GC226_RS23420 WP_000633668.1 4827144..4827734(-) (letA) [Escherichia coli strain 4]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAACTGCTAAGCCAGCTGCCGAAAGGTATGGCGACAATAATGCTCTCTGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTCTCCAAACGCTGTAGCCCTGACGA
ACTGATTGCGGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGCGAACGGCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCTGCC
GAACTGGGCTTGTCGCCGAAAACGGTGCACGTCCATCGCGCCAACCTGATGGAAAAACTGGGTGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378

Multiple sequence alignment