Detailed information NTG0034382

Bioinformatically predicted

Overview

• Name: vicK
• Type: Regulator
• Locus tag: SDEG_RS02835
• Genome accession: NC_012891
• Coordinates: 538780..540132 (+)
• Length: 450 a.a.
• NCBI ID: WP_012766683.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae subsp. equisimilis GGS_124
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 533780..545132

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SDEG_RS02810 (SDEG_0564)	-	534849..535495 (-)	647	Protein_513	amino acid ABC transporter permease	-
SDEG_RS02815 (SDEG_0566)	-	535510..536211 (-)	702	WP_012766679.1	amino acid ABC transporter permease	-
SDEG_RS02820 (SDEG_0567)	-	536225..537025 (-)	801	WP_003057243.1	transporter substrate-binding domain-containing protein	-
SDEG_RS02825 (SDEG_0568)	-	537025..537819 (-)	795	WP_041788867.1	amino acid ABC transporter ATP-binding protein	-
SDEG_RS02830 (SDEG_0569)	vicR	538077..538787 (+)	711	WP_012766682.1	response regulator YycF	Regulator
SDEG_RS02835 (SDEG_0570)	vicK	538780..540132 (+)	1353	WP_012766683.1	cell wall metabolism sensor histidine kinase VicK	Regulator
SDEG_RS02840 (SDEG_0571)	vicX	540136..540945 (+)	810	WP_003059746.1	MBL fold metallo-hydrolase	Regulator
SDEG_RS02845 (SDEG_0572)	rnc	541703..542395 (+)	693	WP_003057240.1	ribonuclease III	-

Sequence

Protein

• Length: 450 a.a.
• Molecular weight: 51467.05 Da
• Isoelectric Point: 5.5741

>NTDB_id=34382 SDEG_RS02835 WP_012766683.1 538780..540132(+) (vicK) [Streptococcus dysgalactiae subsp. equisimilis GGS_124]
MTRDIIGNLSAFELAILLLLVFVAFYFIHLAVRDYRNARIIRMMSHKIRDLINGRYTDMINEKADIELMELADQLNDLSD
VFRLTHENLAQEKNRLASILAYMSDGVLATDRSGKIIMINETARKQLNLTKEKALEKNITDLLEGDTPYTYRELVSKTPV
VTVNSRNDMGEFVTLRLRFALNRRESGFISGLVVVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGAIK
EDIAPSFIKVSLDETNRMMRMISDLLNLSRIDNQVTQLSVEMTNFTAFMTSILNRFDLVKNQQTGTGKVYEIVRDYPITS
VWLEIDNDKMTQVIENILNNAIKYSPDGGKITVRMKTTDTQLIISISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTG
LGLAIAKEIIKQHHGFIWAKSDYGKGSTFTIVLPYEKDAAIYEEWEDDID

Nucleotide

• Length: 1353 bp

>NTDB_id=34382 SDEG_RS02835 WP_012766683.1 538780..540132(+) (vicK) [Streptococcus dysgalactiae subsp. equisimilis GGS_124]
ATGACTAGAGATATCATTGGAAACTTATCTGCTTTTGAATTAGCGATTCTCTTATTACTTGTTTTTGTTGCCTTTTATTT
TATTCACTTAGCGGTGCGTGATTACCGAAATGCCCGTATTATTCGAATGATGAGCCATAAAATCAGAGACCTGATTAATG
GCCGTTATACCGACATGATTAACGAAAAGGCTGACATTGAATTGATGGAACTGGCAGATCAGTTAAACGATCTCTCAGAC
GTGTTTCGCTTAACCCATGAGAATCTTGCCCAGGAAAAAAATCGCTTGGCCAGCATTCTGGCCTATATGTCAGATGGCGT
ACTTGCCACAGACCGTTCTGGGAAAATCATCATGATTAACGAGACTGCCCGCAAGCAGCTCAATCTGACCAAGGAGAAGG
CCCTTGAAAAGAACATTACCGATTTGTTGGAGGGAGATACCCCCTATACCTATCGTGAATTGGTTTCCAAAACGCCTGTT
GTGACGGTCAATAGTCGCAATGACATGGGTGAGTTTGTTACATTACGTTTACGCTTCGCCTTAAACAGACGAGAAAGTGG
TTTTATTTCTGGTTTGGTTGTGGTGCTCCATGACACTACAGAACAGGAAAAGGAAGAACGTGAACGCCGGTTGTTTGTTT
CTAATGTGAGTCATGAGTTGAGAACACCTTTGACATCGGTGAAATCCTACTTGGAGGCTCTTGACGAAGGTGCCATCAAG
GAAGATATTGCTCCAAGTTTCATAAAAGTTTCTCTTGATGAAACCAATCGGATGATGCGTATGATTTCCGATCTTTTAAA
CTTGTCTCGCATTGATAACCAAGTAACTCAGTTATCTGTCGAGATGACCAATTTTACAGCTTTTATGACATCTATCCTGA
ACCGATTTGACCTAGTTAAAAACCAGCAAACCGGTACTGGCAAGGTTTATGAAATTGTGAGAGACTATCCGATTACCTCT
GTTTGGCTGGAAATTGATAATGATAAGATGACGCAGGTTATTGAAAATATCCTAAACAACGCGATTAAATACTCTCCTGA
TGGTGGGAAAATCACTGTTCGCATGAAAACAACCGACACGCAATTGATTATTTCCATCTCAGACCAAGGCTTAGGCATTC
CGAAGAAGGATCTGCCCCTTATTTTTGACCGTTTTTACCGTGTGGACAAGGCAAGAAGCCGTGCTCAAGGTGGAACTGGT
CTAGGGCTTGCCATTGCCAAAGAAATTATTAAGCAGCATCACGGGTTTATTTGGGCGAAGAGTGATTATGGCAAAGGATC
AACCTTTACCATCGTCTTGCCATATGAAAAAGATGCTGCCATTTACGAAGAGTGGGAGGATGACATAGATTAA

Domains

Predicted by InterproScan.

• His Kinase A (phospho-acceptor) domain (HisKA) (209-273)

• PAS fold (PAS) (95-165)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (326-436)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicK	Streptococcus mutans UA159	73.43	92	0.676
micB	Streptococcus pneumoniae Cp1015	66.588	94.444	0.629