Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   FNW43_RS13190 Genome accession   NZ_CP044410
Coordinates   2699477..2700133 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain ecMN1F     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2694477..2705133
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FNW43_RS13160 (FNW43_13160) yecA 2695728..2696393 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  FNW43_RS13180 (FNW43_13180) pgsA 2697043..2697591 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  FNW43_RS13185 (FNW43_13185) uvrC 2697648..2699480 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  FNW43_RS13190 (FNW43_13190) letA 2699477..2700133 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  FNW43_RS23190 - 2700275..2700346 (+) 72 Protein_2585 transcriptional regulator -
  FNW43_RS13195 (FNW43_13195) - 2700544..2701524 (-) 981 WP_000019403.1 IS5-like element IS5 family transposase -
  FNW43_RS13200 (FNW43_13200) yecU 2701628..2701804 (+) 177 WP_000590347.1 protein YecU -
  FNW43_RS13205 (FNW43_13205) yecF 2701791..2702015 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  FNW43_RS13210 (FNW43_13210) sdiA 2702083..2702805 (-) 723 WP_001152715.1 transcriptional regulator SdiA -
  FNW43_RS13215 (FNW43_13215) tcyN 2703035..2703787 (-) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  FNW43_RS13220 (FNW43_13220) tcyL 2703784..2704452 (-) 669 WP_001158220.1 cystine ABC transporter permease -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=342473 FNW43_RS13190 WP_000611335.1 2699477..2700133(-) (letA) [Escherichia coli strain ecMN1F]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=342473 FNW43_RS13190 WP_000611335.1 2699477..2700133(-) (letA) [Escherichia coli strain ecMN1F]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486

Multiple sequence alignment