Detailed information    

insolico Bioinformatically predicted

Overview

Name   sepM   Type   Regulator
Locus tag   ETT45_RS06010 Genome accession   NZ_CP035454
Coordinates   1171099..1172145 (-) Length   348 a.a.
NCBI ID   WP_111711349.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain emm54     
Function   processing of CSP (predicted from homology)   
Competence regulation

Genomic Context

Location: 1166099..1177145
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT45_RS05990 (ETT45_05985) - 1166852..1167478 (+) 627 WP_038434165.1 A24 family peptidase -
  ETT45_RS05995 (ETT45_05990) rlmN 1167560..1168639 (-) 1080 WP_136129657.1 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN -
  ETT45_RS06000 (ETT45_05995) - 1168643..1169263 (-) 621 WP_038434166.1 YutD family protein -
  ETT45_RS06005 (ETT45_06000) - 1169711..1170688 (-) 978 WP_002994809.1 LacI family DNA-binding transcriptional regulator -
  ETT45_RS06010 (ETT45_06005) sepM 1171099..1172145 (-) 1047 WP_111711349.1 SepM family pheromone-processing serine protease Regulator
  ETT45_RS06015 (ETT45_06010) coaD 1172132..1172623 (-) 492 WP_014407698.1 pantetheine-phosphate adenylyltransferase -
  ETT45_RS06020 (ETT45_06015) rsmD 1172613..1173152 (-) 540 WP_002983819.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  ETT45_RS06025 (ETT45_06020) asnA 1173275..1174267 (-) 993 WP_109828593.1 aspartate--ammonia ligase -
  ETT45_RS06030 (ETT45_06025) arcC 1174580..1175530 (-) 951 WP_109828594.1 carbamate kinase -
  ETT45_RS06035 (ETT45_06030) - 1175550..1176881 (-) 1332 WP_136129658.1 dipeptidase -

Sequence

Protein


Download         Length: 348 a.a.        Molecular weight: 37840.57 Da        Isoelectric Point: 9.7472

>NTDB_id=342472 ETT45_RS06010 WP_111711349.1 1171099..1172145(-) (sepM) [Streptococcus pyogenes strain emm54]
MKRLKKIKWWLVGLLALISLLLALFFPLPYYIEMPGGAYDIRTVLQVNGKEDKRKGAYQFVAVGISRASLAQLLYAWLTP
FTEISTAEDTTGGYSDADFLRINQFYMETSQNAAIYQALSLAGKPVTLDYKGVYVLDVNNESTFKGTLHLADTVTGVNGK
QFTSSAELIDYVSHLKLGDEVTVQFTSDNKPKKGVGRIIKLKNGKNGKNGIGIALTDHTSVNSEDTVIFSTKGVGGPSAG
LMFTLDIYDQITKEDLRKGRTIAGTGTIGKDGEVGDIGGAGLKVVAAAEAGADIFFVPNNPVDKEIKKVNPNAISNYEEA
KRAAKRLKTKMKIVPVTTVQEALVYLRK

Nucleotide


Download         Length: 1047 bp        

>NTDB_id=342472 ETT45_RS06010 WP_111711349.1 1171099..1172145(-) (sepM) [Streptococcus pyogenes strain emm54]
ATGAAAAGACTTAAAAAAATCAAATGGTGGTTAGTGGGTCTGCTAGCTTTAATCTCTTTGTTGCTAGCGTTATTTTTTCC
GCTACCTTATTATATTGAAATGCCTGGAGGCGCTTACGATATTCGGACTGTCTTACAAGTCAATGGCAAAGAAGACAAAC
GAAAAGGAGCTTACCAGTTTGTTGCAGTGGGCATTAGTCGTGCCAGCCTCGCTCAGCTATTATATGCTTGGCTGACACCG
TTTACTGAAATTAGTACAGCAGAAGATACAACAGGCGGATACAGCGATGCTGATTTCCTTCGAATTAATCAATTTTACAT
GGAAACATCACAAAATGCAGCTATTTATCAAGCTTTATCCTTAGCTGGAAAACCAGTTACATTAGATTATAAAGGCGTAT
ATGTTTTAGACGTAAACAACGAATCTACTTTTAAAGGAACGCTACACTTAGCAGATACTGTAACAGGTGTAAATGGTAAA
CAGTTTACTAGTTCAGCAGAACTTATTGACTATGTTTCTCACCTAAAACTAGGGGATGAAGTTACGGTTCAGTTTACGAG
TGATAATAAGCCTAAAAAAGGAGTTGGCCGTATTATCAAACTGAAAAATGGGAAAAATGGGAAAAATGGGATTGGCATTG
CCTTGACTGATCATACAAGTGTCAATTCAGAAGACACAGTGATCTTTAGTACTAAAGGAGTAGGAGGACCTAGTGCTGGT
CTAATGTTTACTCTTGATATATATGATCAAATAACTAAAGAAGATTTACGCAAGGGCCGTACAATTGCAGGTACAGGAAC
TATTGGCAAGGATGGCGAAGTAGGAGATATTGGTGGTGCAGGTCTTAAAGTAGTTGCAGCAGCTGAAGCTGGTGCAGATA
TATTTTTTGTTCCGAATAATCCTGTTGATAAGGAAATTAAAAAAGTTAATCCAAATGCTATAAGTAATTACGAAGAAGCC
AAACGGGCAGCCAAACGACTAAAGACCAAAATGAAGATTGTTCCTGTTACGACTGTTCAAGAGGCACTGGTTTATCTTCG
CAAATAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(129-192)

Lon protease (S16) C-terminal proteolytic domain (Lon_C)

(236-312)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sepM Streptococcus mutans UA159

68.678

100

0.687

Multiple sequence alignment