Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   F7O57_RS22875 Genome accession   NZ_CP044403
Coordinates   4634862..4635494 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain NMBU-W10C18     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4629862..4640494
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  F7O57_RS22850 (F7O57_23285) yheS 4630031..4631944 (+) 1914 WP_020232893.1 ABC transporter ATP-binding protein -
  F7O57_RS22855 (F7O57_23290) yheT 4631944..4632966 (+) 1023 WP_001521449.1 hydrolase -
  F7O57_RS22860 (F7O57_23295) yheU 4632960..4633178 (+) 219 WP_000907085.1 YheU family protein -
  F7O57_RS22865 (F7O57_23300) prkB 4633232..4634101 (+) 870 WP_001274680.1 phosphoribulokinase -
  F7O57_RS22870 (F7O57_23305) yhfA 4634156..4634560 (-) 405 WP_001148908.1 OsmC family protein -
  F7O57_RS22875 (F7O57_23310) crp 4634862..4635494 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  F7O57_RS22880 (F7O57_23315) yhfK 4635545..4637635 (+) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  F7O57_RS22885 (F7O57_23320) argD 4637702..4638922 (-) 1221 WP_000963771.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  F7O57_RS22890 (F7O57_23325) pabA 4639008..4639571 (-) 564 WP_001521451.1 aminodeoxychorismate synthase component 2 -
  F7O57_RS22895 (F7O57_23330) fic 4639603..4640205 (-) 603 WP_001280641.1 putative adenosine monophosphate-protein transferase Fic -
  F7O57_RS22900 (F7O57_23335) yhfG 4640195..4640362 (-) 168 WP_000736860.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=342422 F7O57_RS22875 WP_000242755.1 4634862..4635494(+) (crp) [Escherichia coli strain NMBU-W10C18]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=342422 F7O57_RS22875 WP_000242755.1 4634862..4635494(+) (crp) [Escherichia coli strain NMBU-W10C18]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGCCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCGGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATAGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment