Detailed information NTG0342340

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: BACIH_RS18915
• Genome accession: NZ_CP044360
• Coordinates: 3794629..3795825 (-)
• Length: 398 a.a.
• NCBI ID: WP_012118892.1
• Uniprot ID: A7ZAN8
• Organism: Bacillus amyloliquefaciens strain V167
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 3789629..3800825

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BACIH_RS18895 (BACIH_3871)	-	3789935..3791257 (-)	1323	WP_012118888.1	ABC transporter substrate-binding protein	-
BACIH_RS18900 (BACIH_3872)	-	3791254..3792261 (-)	1008	WP_023357221.1	ThiF family adenylyltransferase	-
BACIH_RS18905 (BACIH_3873)	-	3792493..3793911 (-)	1419	WP_012118890.1	cell wall metabolism sensor histidine kinase WalK	-
BACIH_RS18910 (BACIH_3874)	-	3793908..3794117 (-)	210	WP_012118891.1	winged helix-turn-helix domain-containing protein	-
BACIH_RS18915 (BACIH_3876)	htrA	3794629..3795825 (-)	1197	WP_012118892.1	S1C family serine protease	Regulator
BACIH_RS18920 (BACIH_3877)	vicX	3795912..3796706 (-)	795	WP_007407895.1	MBL fold metallo-hydrolase	Regulator
BACIH_RS18925 (BACIH_3878)	-	3796721..3797560 (-)	840	WP_012118893.1	two-component system regulatory protein YycI	-
BACIH_RS18930 (BACIH_3879)	yycH	3797547..3798905 (-)	1359	WP_004393107.1	two-component system activity regulator YycH	-
BACIH_RS18935 (BACIH_3880)	walK	3798895..3800730 (-)	1836	WP_004393106.1	cell wall metabolism sensor histidine kinase WalK	-

Sequence

Protein

• Length: 398 a.a.
• Molecular weight: 42591.36 Da
• Isoelectric Point: 6.9987

>NTDB_id=342340 BACIH_RS18915 WP_012118892.1 3794629..3795825(-) (htrA) [Bacillus amyloliquefaciens strain V167]
MDYNRDDEQYASEQPRRSKRGYFLSSLIGVIVGAALMAFLLPYWTGGDHGENSKSTSQRLGSEQVKTVNVNVNDAVTNMV
SRVSDSVVGVLNIQKTDIWGEGGEAGSGSGVIYKKNGNTSYIVTNHHVIEGATEIEISLKDGSRVPAELIGSDSLMDLAV
LKVKSDKIKSAAQFGNSDQVKVGEPVIAIGNPLGLEFAGSVTQGIISGTERAVPVDSNGDGQPDWNAEVLQTDAAINPGN
SGGALMDISGKVVGINSMKIAESAVEGIGLSIPSKLVIPVIQDLEKYGEVRRPFLGIEMKSLTDIASYHWSQTLKLPKGV
KTGAVIMGVDAFSPAGKAGLKKLDVITGFDGHKVNDVVDLRERLYRKKIGDRVNITFYRSGKKKTAEVKLTEADRLQK

Nucleotide

• Length: 1197 bp

>NTDB_id=342340 BACIH_RS18915 WP_012118892.1 3794629..3795825(-) (htrA) [Bacillus amyloliquefaciens strain V167]
GTGGATTATAATCGCGATGATGAACAGTACGCCTCCGAACAGCCCCGCCGCAGCAAGAGAGGGTACTTTCTATCAAGTCT
GATCGGCGTCATCGTCGGGGCCGCGCTCATGGCTTTCCTGCTGCCGTACTGGACAGGCGGAGATCATGGAGAAAACAGCA
AAAGCACCAGCCAGCGTCTCGGCAGCGAACAGGTGAAAACAGTCAACGTAAATGTCAATGACGCTGTCACGAATATGGTC
AGCCGTGTATCAGATTCGGTAGTCGGCGTTCTCAATATCCAAAAGACCGATATTTGGGGAGAGGGCGGCGAAGCGGGAAG
CGGGTCGGGCGTCATTTACAAAAAGAACGGAAACACTTCTTATATCGTAACCAATCACCATGTCATTGAAGGTGCGACTG
AGATTGAGATCAGCCTGAAGGATGGCTCACGCGTGCCTGCTGAGCTGATCGGGAGCGACAGTCTGATGGATCTCGCTGTG
CTGAAGGTGAAATCTGATAAAATCAAATCGGCCGCCCAGTTCGGCAATTCCGATCAGGTCAAAGTCGGAGAACCGGTCAT
TGCGATCGGAAATCCGCTTGGGCTTGAATTTGCGGGATCAGTGACACAGGGGATCATTTCAGGCACGGAAAGGGCGGTGC
CCGTTGACTCAAACGGCGACGGACAGCCGGATTGGAATGCGGAAGTGCTGCAGACCGATGCCGCGATTAACCCCGGCAAC
AGCGGCGGCGCTTTGATGGATATATCGGGCAAGGTGGTCGGCATCAACTCAATGAAGATCGCTGAATCCGCCGTTGAAGG
GATCGGCCTGTCCATCCCGTCAAAGCTTGTCATTCCCGTTATTCAGGATTTAGAAAAATACGGAGAAGTCAGACGGCCTT
TCCTCGGTATTGAGATGAAATCCTTAACGGATATTGCGAGCTACCATTGGAGCCAGACGCTGAAACTTCCGAAAGGCGTT
AAAACCGGGGCGGTCATTATGGGTGTCGACGCGTTTTCACCGGCCGGAAAAGCGGGTTTGAAAAAGCTTGACGTAATCAC
CGGGTTCGACGGACATAAGGTCAATGACGTTGTGGATCTCCGTGAGCGCCTGTATCGCAAAAAGATCGGTGACCGTGTGA
ACATCACGTTCTACCGTTCGGGAAAGAAAAAAACAGCGGAAGTCAAACTGACAGAAGCGGATCGATTACAGAAATAA

Domains

Predicted by InterProScan.

• Peptidase family M50 (Peptidase_M50) (265-394)

• PDZ domain (PDZ_2) (293-390)

• Trypsin-like peptidase domain (Trypsin_2) (108-255)

3D structure

• AlphaFold DB: A7ZAN8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	43.939	99.497	0.437
htrA	Streptococcus gordonii str. Challis substr. CH1	40.052	97.236	0.389
htrA	Streptococcus mitis NCTC 12261	43.636	82.915	0.362