Detailed information NTG0342230

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: ETT49_RS01380
• Genome accession: NZ_CP035450
• Coordinates: 252289..253359 (+)
• Length: 356 a.a.
• NCBI ID: WP_023612409.1
• Uniprot ID: A0A5S4TIQ7
• Organism: Streptococcus pyogenes strain emm93.4
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 247289..258359

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ETT49_RS01365 (ETT49_01365)	amiA	247808..249787 (+)	1980	WP_136269440.1	peptide ABC transporter substrate-binding protein	Regulator
ETT49_RS01370 (ETT49_01370)	amiC	249852..251354 (+)	1503	WP_011017334.1	ABC transporter permease	Regulator
ETT49_RS01375 (ETT49_01375)	amiD	251354..252280 (+)	927	WP_002986004.1	oligopeptide ABC transporter permease OppC	Regulator
ETT49_RS01380 (ETT49_01380)	amiE	252289..253359 (+)	1071	WP_023612409.1	ABC transporter ATP-binding protein	Regulator
ETT49_RS01385 (ETT49_01385)	amiF	253352..254275 (+)	924	WP_109828499.1	ABC transporter ATP-binding protein	Regulator
ETT49_RS08810 (ETT49_01390)	-	254313..254396 (-)	84	Protein_224	IS3 family transposase	-

Sequence

Protein

• Length: 356 a.a.
• Molecular weight: 39689.75 Da
• Isoelectric Point: 5.6686

>NTDB_id=342230 ETT49_RS01380 WP_023612409.1 252289..253359(+) (amiE) [Streptococcus pyogenes strain emm93.4]
MTKENNVILTAKDVVVEFDVRDRVLTAIRNVSLELVEGEVLAFVGESGSGKSVLTKTFTGMLESNGRIANGSIVYRGQEL
TDLKTNKEWAKIRGSKIATIFQDPMTSLSPIKTIGSQITEVIIKHQKVSHAKAKEMALDYMNKVGIPNAKKRFEDYPFEY
SGGMRQRIVIAIALACRPDILICDEPTTALDVTIQAQIVELLKSLQREYHFTIIFITHDLGVVASIADKVAVMYAGEIVE
FGTVEEIFYDPRHPYTWSLLSSLPQLADDSGELYAIPGTPPSLYSPIIGDAFALRSEYAMVLDFEKAPPAINVSETHWAK
TWLLHPEAPKVQKPEVIQDLHQKILRKMSQQEEGNV

Nucleotide

• Length: 1071 bp

>NTDB_id=342230 ETT49_RS01380 WP_023612409.1 252289..253359(+) (amiE) [Streptococcus pyogenes strain emm93.4]
ATGACAAAAGAAAATAATGTAATCTTAACTGCCAAAGATGTGGTGGTAGAATTTGATGTGCGTGATCGTGTTTTAACAGC
TATCCGTAACGTCTCACTGGAACTTGTTGAAGGAGAAGTCCTTGCTTTTGTAGGGGAATCAGGCTCAGGTAAATCTGTTT
TAACAAAGACCTTTACAGGGATGTTGGAGTCTAATGGACGCATTGCTAATGGTTCAATTGTCTATCGTGGGCAAGAATTG
ACAGATTTAAAAACAAATAAAGAGTGGGCAAAGATTCGCGGCTCAAAAATCGCAACGATTTTCCAAGACCCAATGACCAG
TCTTAGTCCCATTAAAACTATCGGTAGCCAAATCACAGAAGTGATTATTAAGCACCAAAAAGTAAGTCATGCCAAAGCTA
AAGAAATGGCCCTTGATTACATGAATAAAGTGGGTATCCCAAATGCCAAAAAACGCTTTGAAGATTACCCATTTGAGTAT
TCAGGAGGAATGCGTCAACGTATTGTTATCGCTATTGCTTTAGCTTGTCGCCCAGATATTCTTATCTGTGATGAGCCAAC
AACAGCCCTTGATGTGACTATTCAAGCTCAAATCGTTGAGTTATTGAAGTCGCTTCAACGAGAATATCATTTCACCATTA
TCTTTATTACGCACGATTTAGGTGTTGTGGCAAGCATTGCAGATAAAGTGGCTGTCATGTATGCAGGAGAAATTGTTGAA
TTTGGAACAGTCGAAGAGATTTTCTATGATCCAAGACACCCCTATACATGGAGTTTGCTGTCTAGCTTACCGCAGTTGGC
AGATGATTCTGGTGAACTTTACGCTATTCCAGGAACGCCTCCATCACTTTATTCACCAATTATCGGAGATGCCTTTGCAC
TTCGCTCAGAATATGCTATGGTTTTAGACTTTGAAAAAGCACCTCCGGCGATTAACGTATCTGAGACTCATTGGGCCAAA
ACATGGCTTTTACACCCAGAGGCTCCAAAAGTTCAAAAACCAGAAGTCATTCAAGATTTGCATCAAAAAATCTTAAGGAA
AATGTCACAACAGGAGGAAGGAAATGTCTGA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (29-187)

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-299)

3D structure

• AlphaFold DB: A0A5S4TIQ7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	76.944	100	0.778
amiE	Streptococcus thermophilus LMG 18311	75.833	100	0.767
amiE	Streptococcus thermophilus LMD-9	75.833	100	0.767
oppD	Streptococcus mutans UA159	56.677	94.663	0.537