Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   F7D02_RS25050 Genome accession   NZ_CP044315
Coordinates   4990400..4990990 (+) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain SJ7     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4985400..4995990
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  F7D02_RS25025 (F7D02_25615) emrD 4985882..4987066 (-) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -
  F7D02_RS27950 ysdE 4987148..4987222 (+) 75 WP_211180519.1 protein YsdE -
  F7D02_RS25030 (F7D02_25620) tisB 4987485..4987574 (-) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  F7D02_RS25035 (F7D02_25625) ivbL 4988139..4988237 (+) 99 WP_001315912.1 ilvB operon leader peptide IvbL -
  F7D02_RS25040 (F7D02_25630) ilvB 4988343..4990031 (+) 1689 WP_000168480.1 acetolactate synthase large subunit -
  F7D02_RS25045 (F7D02_25635) ilvN 4990035..4990325 (+) 291 WP_001181706.1 acetolactate synthase small subunit -
  F7D02_RS25050 (F7D02_25640) letA 4990400..4990990 (+) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  F7D02_RS25055 (F7D02_25645) uhpB 4990990..4992492 (+) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  F7D02_RS25060 (F7D02_25650) uhpC 4992502..4993821 (+) 1320 WP_000936565.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  F7D02_RS25065 (F7D02_25655) uhpT 4993959..4995350 (+) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=342132 F7D02_RS25050 WP_000633668.1 4990400..4990990(+) (letA) [Escherichia coli strain SJ7]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=342132 F7D02_RS25050 WP_000633668.1 4990400..4990990(+) (letA) [Escherichia coli strain SJ7]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAACTGCTAAGCCAGCTGCCGAAAGGTATGGCGACAATAATGCTCTCTGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCGCGCGGCTTTCTCTCCAAACGCTGTAGCCCTGACGA
ACTGATTGCGGCGGTGCATACGGTTGCTACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTGACCAAACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTAGA
ACTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378