Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   F7D05_RS22245 Genome accession   NZ_CP044312
Coordinates   4495416..4496048 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain RM13745     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4490416..4501048
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  F7D05_RS22220 (F7D05_22610) yheS 4490585..4492498 (+) 1914 WP_000634793.1 ABC transporter ATP-binding protein -
  F7D05_RS22225 (F7D05_22615) yheT 4492498..4493520 (+) 1023 WP_000057356.1 hydrolase -
  F7D05_RS22230 (F7D05_22620) yheU 4493514..4493732 (+) 219 WP_000907085.1 YheU family protein -
  F7D05_RS22235 (F7D05_22625) prkB 4493786..4494655 (+) 870 WP_001274684.1 phosphoribulokinase -
  F7D05_RS22240 (F7D05_22630) yhfA 4494710..4495114 (-) 405 WP_001148908.1 OsmC family protein -
  F7D05_RS22245 (F7D05_22635) crp 4495416..4496048 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  F7D05_RS22250 (F7D05_22640) yhfK 4496099..4498189 (+) 2091 WP_001297515.1 YccS/YhfK family putative transporter -
  F7D05_RS22255 (F7D05_22645) argD 4498256..4499476 (-) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  F7D05_RS22260 (F7D05_22650) pabA 4499563..4500126 (-) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  F7D05_RS22265 (F7D05_22655) fic 4500158..4500760 (-) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  F7D05_RS22270 (F7D05_22660) yhfG 4500750..4500917 (-) 168 WP_000736860.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=341885 F7D05_RS22245 WP_000242755.1 4495416..4496048(+) (crp) [Escherichia coli strain RM13745]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=341885 F7D05_RS22245 WP_000242755.1 4495416..4496048(+) (crp) [Escherichia coli strain RM13745]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment