Detailed information NTG0341874

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: ETT56_RS07510
• Genome accession: NZ_CP035443
• Coordinates: 1459620..1460621 (-)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain emm58
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1454620..1465621

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ETT56_RS07495 (ETT56_07490)	thrS	1454790..1456733 (-)	1944	WP_002985672.1	threonine--tRNA ligase	-
ETT56_RS07500 (ETT56_07495)	-	1457155..1458489 (-)	1335	WP_002994187.1	glycosyltransferase family 4 protein	-
ETT56_RS07505 (ETT56_07500)	-	1458491..1459489 (-)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
ETT56_RS07510 (ETT56_07505)	ccpA	1459620..1460621 (-)	1002	WP_002985680.1	catabolite control protein A	Regulator
ETT56_RS07515 (ETT56_07510)	-	1460795..1461880 (+)	1086	WP_002985682.1	aminopeptidase P family protein	-
ETT56_RS07520 (ETT56_07515)	-	1461929..1462594 (+)	666	WP_002985684.1	NAD(P)H-dependent oxidoreductase	-
ETT56_RS07525 (ETT56_07520)	-	1462605..1462982 (+)	378	WP_002985686.1	VOC family protein	-
ETT56_RS07530 (ETT56_07525)	-	1463127..1464053 (+)	927	WP_002985688.1	glycosyltransferase family 2 protein	-
ETT56_RS07535 (ETT56_07530)	-	1464264..1464947 (+)	684	WP_002990714.1	DUF969 domain-containing protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=341874 ETT56_RS07510 WP_002985680.1 1459620..1460621(-) (ccpA) [Streptococcus pyogenes strain emm58]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=341874 ETT56_RS07510 WP_002985680.1 1459620..1460621(-) (ccpA) [Streptococcus pyogenes strain emm58]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAGTTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTATC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGGTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGTGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559