Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   F7D06_RS20260 Genome accession   NZ_CP044311
Coordinates   4105181..4105771 (-) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain RM13752     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4100181..4110771
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  F7D06_RS20245 (F7D06_20610) uhpT 4100821..4102212 (-) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -
  F7D06_RS20250 (F7D06_20615) uhpC 4102350..4103669 (-) 1320 WP_000936566.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  F7D06_RS20255 (F7D06_20620) uhpB 4103679..4105181 (-) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  F7D06_RS20260 (F7D06_20625) letA 4105181..4105771 (-) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  F7D06_RS20265 (F7D06_20630) ilvN 4105846..4106136 (-) 291 WP_001181706.1 acetolactate synthase small subunit -
  F7D06_RS20270 (F7D06_20635) ilvB 4106140..4107723 (-) 1584 Protein_4016 acetolactate synthase large subunit -
  F7D06_RS26480 ysdE 4108759..4108833 (-) 75 WP_211180519.1 protein YsdE -
  F7D06_RS20275 (F7D06_20640) emrD 4108915..4110099 (+) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -
  F7D06_RS20280 (F7D06_20645) yidF 4110107..4110604 (-) 498 WP_050939667.1 radical SAM protein -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=341803 F7D06_RS20260 WP_000633668.1 4105181..4105771(-) (letA) [Escherichia coli strain RM13752]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=341803 F7D06_RS20260 WP_000633668.1 4105181..4105771(-) (letA) [Escherichia coli strain RM13752]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAACTGCTAAGCCAGCTGCCGAAAGGTATGGCGACAATAATGCTCTCTGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTCTCCAAACGCTGTAGCCCTGACGA
ACTGATTGCGGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGCGAACGGCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCTGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTAGA
ACTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378

Multiple sequence alignment