Detailed information NTG0341801

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: ETT57_RS02300
• Genome accession: NZ_CP035442
• Coordinates: 411579..412580 (+)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain emm25
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 406579..417580

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ETT57_RS02275 (ETT57_02270)	-	407253..407936 (-)	684	WP_053308560.1	DUF969 domain-containing protein	-
ETT57_RS02280 (ETT57_02275)	-	408147..409073 (-)	927	WP_053308559.1	glycosyltransferase family 2 protein	-
ETT57_RS02285 (ETT57_02280)	-	409218..409595 (-)	378	WP_002985686.1	VOC family protein	-
ETT57_RS02290 (ETT57_02285)	-	409606..410271 (-)	666	WP_002985684.1	NAD(P)H-dependent oxidoreductase	-
ETT57_RS02295 (ETT57_02290)	-	410320..411405 (-)	1086	WP_136048498.1	aminopeptidase P family protein	-
ETT57_RS02300 (ETT57_02295)	ccpA	411579..412580 (+)	1002	WP_002985680.1	catabolite control protein A	Regulator
ETT57_RS02305 (ETT57_02300)	-	412711..413709 (+)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
ETT57_RS02310 (ETT57_02305)	-	413711..415045 (+)	1335	WP_053308557.1	glycosyltransferase family 4 protein	-
ETT57_RS02315 (ETT57_02310)	thrS	415467..417410 (+)	1944	WP_053308556.1	threonine--tRNA ligase	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=341801 ETT57_RS02300 WP_002985680.1 411579..412580(+) (ccpA) [Streptococcus pyogenes strain emm25]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=341801 ETT57_RS02300 WP_002985680.1 411579..412580(+) (ccpA) [Streptococcus pyogenes strain emm25]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAATTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGTTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCGGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATTATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559