Detailed information NTG0341702

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: ETT59_RS04495
• Genome accession: NZ_CP035440
• Coordinates: 886621..887457 (-)
• Length: 278 a.a.
• NCBI ID: WP_136305960.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain emm124
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 881621..892457

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ETT59_RS04470 (ETT59_04470)	-	881839..882831 (-)	993	WP_009880715.1	D-lactate dehydrogenase	-
ETT59_RS04475 (ETT59_04475)	-	882846..883412 (-)	567	Protein_801	PTS sugar transporter subunit IIC	-
ETT59_RS09000	-	883452..884309 (+)	858	Protein_802	LysR family transcriptional regulator	-
ETT59_RS04490 (ETT59_04490)	topA	884384..886513 (-)	2130	WP_014407586.1	type I DNA topoisomerase	-
ETT59_RS04495 (ETT59_04495)	dprA	886621..887457 (-)	837	WP_136305960.1	DNA-processing protein DprA	Machinery gene
ETT59_RS04500 (ETT59_04500)	-	887522..888313 (-)	792	WP_136276364.1	ribonuclease HII	-
ETT59_RS04505 (ETT59_04505)	ylqF	888303..889151 (-)	849	WP_014407584.1	ribosome biogenesis GTPase YlqF	-
ETT59_RS04510 (ETT59_04510)	-	889370..889810 (+)	441	WP_085634295.1	DUF1836 domain-containing protein	-
ETT59_RS04515 (ETT59_04515)	-	889807..890457 (+)	651	WP_136047671.1	hemolysin III family protein	-
ETT59_RS04520 (ETT59_04520)	-	890574..891485 (+)	912	WP_136047672.1	diacylglycerol kinase family protein	-
ETT59_RS04525 (ETT59_04525)	-	891535..891903 (-)	369	WP_010922310.1	hypothetical protein	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 31022.96 Da
• Isoelectric Point: 8.8230

>NTDB_id=341702 ETT59_RS04495 WP_136305960.1 886621..887457(-) (dprA) [Streptococcus pyogenes strain emm124]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNIFDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=341702 ETT59_RS04495 WP_136305960.1 886621..887457(-) (dprA) [Streptococcus pyogenes strain emm124]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAATCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTTGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.266	100	0.673
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis SK321	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.072	100	0.601
dprA	Lactococcus lactis subsp. cremoris KW2	57.554	100	0.576
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367