Detailed information NTG0341550

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: ETT62_RS06945
• Genome accession: NZ_CP035437
• Coordinates: 1382009..1383010 (-)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain emm78.3
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1377009..1388010

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ETT62_RS06930 (ETT62_06925)	thrS	1377179..1379122 (-)	1944	WP_030126096.1	threonine--tRNA ligase	-
ETT62_RS06935 (ETT62_06930)	-	1379544..1380878 (-)	1335	WP_002985676.1	glycosyltransferase family 4 protein	-
ETT62_RS06940 (ETT62_06935)	-	1380880..1381878 (-)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
ETT62_RS06945 (ETT62_06940)	ccpA	1382009..1383010 (-)	1002	WP_002985680.1	catabolite control protein A	Regulator
ETT62_RS06950 (ETT62_06945)	-	1383184..1384269 (+)	1086	WP_085634187.1	aminopeptidase P family protein	-
ETT62_RS06955 (ETT62_06950)	-	1384318..1384984 (+)	667	Protein_1280	NAD(P)H-dependent oxidoreductase	-
ETT62_RS06960 (ETT62_06955)	-	1384995..1385372 (+)	378	WP_002985686.1	VOC family protein	-
ETT62_RS06965 (ETT62_06960)	-	1385517..1386443 (+)	927	WP_136120970.1	glycosyltransferase family 2 protein	-
ETT62_RS06970 (ETT62_06965)	-	1386654..1387337 (+)	684	WP_023078761.1	DUF969 domain-containing protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=341550 ETT62_RS06945 WP_002985680.1 1382009..1383010(-) (ccpA) [Streptococcus pyogenes strain emm78.3]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=341550 ETT62_RS06945 WP_002985680.1 1382009..1383010(-) (ccpA) [Streptococcus pyogenes strain emm78.3]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAGTTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAATGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGTTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559