Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   SALIVB_RS00375 Genome accession   NC_015760
Coordinates   61345..63282 (+) Length   645 a.a.
NCBI ID   WP_013989913.1    Uniprot ID   -
Organism   Streptococcus salivarius CCHSS3     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 56345..68282
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SALIVB_RS00345 (SALIVB_0067) argR 56548..56976 (+) 429 WP_170314548.1 arginine repressor -
  SALIVB_RS00350 (SALIVB_0068) - 56976..57335 (+) 360 WP_013989908.1 YlbF family regulator -
  SALIVB_RS00355 (SALIVB_0069) hexA 57355..59886 (+) 2532 WP_414820285.1 DNA mismatch repair protein MutS Machinery gene
  SALIVB_RS00360 (SALIVB_0070) - 59920..60375 (-) 456 WP_013989910.1 DUF3021 domain-containing protein -
  SALIVB_RS00365 (SALIVB_0071) - 60372..60809 (-) 438 WP_013989911.1 LytTR family DNA-binding domain-containing protein -
  SALIVB_RS00370 (SALIVB_0072) - 60988..61293 (+) 306 WP_013989912.1 hypothetical protein -
  SALIVB_RS00375 (SALIVB_0073) hexB 61345..63282 (+) 1938 WP_013989913.1 DNA mismatch repair endonuclease MutL Machinery gene
  SALIVB_RS00380 (SALIVB_0074) - 63413..63634 (+) 222 WP_013989914.1 hypothetical protein -
  SALIVB_RS00385 (SALIVB_0075) ruvA 63792..64382 (+) 591 WP_013989915.1 Holliday junction branch migration protein RuvA Machinery gene
  SALIVB_RS00390 (SALIVB_0076) - 64391..64945 (+) 555 WP_013989916.1 DNA-3-methyladenine glycosylase I -
  SALIVB_RS00395 (SALIVB_0077) cinA 65042..66307 (+) 1266 WP_013989917.1 competence/damage-inducible protein A Machinery gene
  SALIVB_RS00400 (SALIVB_0078) recA 66348..67487 (+) 1140 WP_013989918.1 recombinase RecA Machinery gene
  SALIVB_RS00405 (SALIVB_0079) spx 67656..68054 (+) 399 WP_002886328.1 transcriptional regulator Spx -

Sequence

Protein


Download         Length: 645 a.a.        Molecular weight: 72316.32 Da        Isoelectric Point: 5.1975

>NTDB_id=34155 SALIVB_RS00375 WP_013989913.1 61345..63282(+) (hexB) [Streptococcus salivarius CCHSS3]
MPKIIELSEVLANQIAAGEVVERPASVVKELVENAIDAGSTQITIEVEESGLSKIQITDNGEGMAQADVAMSLRRHATSK
IKNQGDLFRIRTLGFRGEALPSIASISHLTIVTAADGEAYGTKLVAKGGEIESQDPISTPVGTKITVENLFYNTPARLKY
MKSLQAELAHIVDVVNRLSLAHPEVAFTLLNDGRQLTQTSGTGDLRQAIAGIYGLTTAKKMVEISNSDLDFEVSGYVSLP
ELTRANRNYITILINGRYIKNFLLNRAIFDGYGSKLMVGRFPIAVIDIQIDPYLADVNVHPTKQEVRISKEKELMALISS
AIAQSLREQDLIPDALENLAKSSTRGATKPVQTSLPLKQTNLYYDSSRNDFFVKPETVQEDIKPLVSESPVSSVENKPQP
SVKQAQRLADDSDSEHEKLDYKNKSKMKRMLENLDNEETSTFPELEFFGQMHGTYLFAQGQGGLYIIDQHAAQERVKYEY
YRENIGEVDSSLQQLLVPYLFEFSGSDYISLQEKMPLLNQVGIYLEPYGNNTFILREHPIWMKEEEIESAVYEMCDMLLL
TNEVSVKTYRAELAIMMSCKRSIKANHALDDYSARDLLVQLAQCKNPYNCPHGRPVLVNFTKSDMEKMFRRIQENHTSLR
DLGKY

Nucleotide


Download         Length: 1938 bp        

>NTDB_id=34155 SALIVB_RS00375 WP_013989913.1 61345..63282(+) (hexB) [Streptococcus salivarius CCHSS3]
ATGCCAAAAATCATCGAATTGTCTGAGGTGCTAGCCAACCAGATTGCTGCTGGAGAGGTCGTAGAGCGACCAGCTAGTGT
AGTTAAAGAGCTGGTGGAAAATGCTATTGATGCAGGCAGCACCCAGATTACTATTGAAGTTGAAGAATCAGGCCTCTCAA
AAATTCAAATTACAGACAATGGCGAAGGAATGGCTCAAGCTGACGTGGCTATGAGTTTGCGCCGTCATGCAACAAGTAAA
ATCAAAAATCAAGGAGACCTCTTTCGTATTCGAACTCTTGGTTTTCGAGGTGAGGCCCTGCCATCAATAGCTTCTATCAG
TCATCTTACCATTGTGACGGCGGCTGATGGAGAAGCCTATGGGACTAAACTGGTTGCCAAGGGTGGGGAAATTGAGAGTC
AGGATCCTATTTCAACACCAGTTGGAACAAAGATTACCGTTGAAAACTTATTTTATAACACCCCAGCTCGTCTCAAGTAT
ATGAAGAGTTTACAGGCTGAGTTGGCTCATATTGTTGATGTTGTCAATCGTCTGAGTCTAGCTCATCCCGAAGTTGCCTT
CACCTTGCTTAATGACGGTCGTCAGTTGACACAGACCTCAGGTACTGGAGACCTCCGCCAAGCGATTGCCGGGATTTATG
GTTTGACAACGGCTAAAAAAATGGTGGAAATTTCAAATTCTGATCTTGATTTTGAAGTTTCTGGCTATGTTAGTCTCCCT
GAGTTGACCCGTGCGAATCGTAACTACATCACGATTCTCATTAACGGACGCTATATAAAAAACTTCCTACTTAACCGTGC
TATTTTTGATGGTTATGGTTCTAAACTTATGGTAGGGCGCTTCCCTATTGCGGTTATTGATATTCAGATTGATCCTTATT
TGGCTGATGTCAATGTTCACCCAACAAAGCAGGAAGTACGTATCTCTAAAGAAAAGGAGCTTATGGCCCTCATCAGCTCT
GCCATTGCTCAAAGCCTTAGAGAGCAGGATTTGATTCCGGATGCCCTTGAAAATCTAGCCAAGTCTAGTACTAGAGGTGC
AACTAAGCCGGTTCAAACCAGTCTTCCACTCAAACAAACCAATCTTTATTATGATAGCAGTCGTAATGATTTCTTTGTCA
AACCAGAGACAGTCCAAGAGGATATCAAACCACTCGTGTCAGAGTCTCCAGTTTCATCGGTAGAAAACAAACCGCAACCT
TCTGTTAAACAAGCACAACGTTTAGCAGATGACAGTGATAGTGAACACGAAAAACTTGATTATAAAAACAAGTCGAAAAT
GAAGCGCATGCTTGAAAATCTGGACAATGAGGAAACCTCAACCTTCCCTGAGTTGGAGTTTTTTGGTCAAATGCATGGAA
CCTATCTATTTGCTCAAGGACAAGGTGGACTTTACATCATTGACCAGCATGCTGCCCAAGAACGTGTCAAGTATGAGTAC
TATCGCGAAAATATTGGTGAGGTTGACAGTAGTTTACAACAGCTTTTGGTTCCCTATCTCTTTGAATTTTCAGGTTCGGA
TTACATTAGTTTACAAGAAAAAATGCCTCTTCTTAATCAGGTTGGTATCTATTTAGAGCCTTATGGGAATAACACCTTCA
TTCTTCGTGAACATCCTATCTGGATGAAGGAAGAAGAGATTGAATCTGCAGTCTATGAGATGTGCGACATGCTTCTTTTG
ACGAATGAAGTGTCTGTTAAGACCTACCGTGCTGAGTTAGCCATCATGATGAGTTGTAAACGTTCAATCAAGGCCAATCA
TGCTCTCGATGATTACTCTGCGCGTGACCTTCTAGTACAGCTTGCACAGTGTAAAAACCCCTACAATTGCCCTCACGGAC
GTCCTGTACTTGTCAATTTTACAAAGTCTGATATGGAAAAAATGTTCCGTCGAATTCAAGAAAATCATACTAGTCTACGT
GACTTAGGGAAGTATTAA

Domains

Predicted by InterProScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-124)

MutL C terminal dimerisation domain (MutL_C)

(446-589)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

69.665

100

0.709

Multiple sequence alignment