Detailed information NTG0034154

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: SALIVB_RS00355
• Genome accession: NC_015760
• Coordinates: 57355..59886 (+)
• Length: 843 a.a.
• NCBI ID: WP_414820285.1
• Uniprot ID: -
• Organism: Streptococcus salivarius CCHSS3
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 52355..64886

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SALIVB_RS00325 (SALIVB_0063)	-	53510..53704 (+)	195	WP_004181980.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
SALIVB_RS00330 (SALIVB_0064)	-	53731..53931 (+)	201	WP_013989905.1	hypothetical protein	-
SALIVB_RS00335 (SALIVB_0065)	-	53924..54079 (+)	156	WP_013989906.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
SALIVB_RS00340 (SALIVB_0066)	argS	54702..56393 (-)	1692	WP_013989907.1	arginine--tRNA ligase	-
SALIVB_RS00345 (SALIVB_0067)	argR	56548..56976 (+)	429	WP_170314548.1	arginine repressor	-
SALIVB_RS00350 (SALIVB_0068)	-	56976..57335 (+)	360	WP_013989908.1	YlbF family regulator	-
SALIVB_RS00355 (SALIVB_0069)	hexA	57355..59886 (+)	2532	WP_414820285.1	DNA mismatch repair protein MutS	Machinery gene
SALIVB_RS00360 (SALIVB_0070)	-	59920..60375 (-)	456	WP_013989910.1	DUF3021 domain-containing protein	-
SALIVB_RS00365 (SALIVB_0071)	-	60372..60809 (-)	438	WP_013989911.1	LytTR family DNA-binding domain-containing protein	-
SALIVB_RS00370 (SALIVB_0072)	-	60988..61293 (+)	306	WP_013989912.1	hypothetical protein	-
SALIVB_RS00375 (SALIVB_0073)	hexB	61345..63282 (+)	1938	WP_013989913.1	DNA mismatch repair endonuclease MutL	Machinery gene
SALIVB_RS00380 (SALIVB_0074)	-	63413..63634 (+)	222	WP_013989914.1	hypothetical protein	-
SALIVB_RS00385 (SALIVB_0075)	ruvA	63792..64382 (+)	591	WP_013989915.1	Holliday junction branch migration protein RuvA	Machinery gene

Sequence

Protein

• Length: 843 a.a.
• Molecular weight: 94655.67 Da
• Isoelectric Point: 4.6344

>NTDB_id=34154 SALIVB_RS00355 WP_414820285.1 57355..59886(+) (hexA) [Streptococcus salivarius CCHSS3]
MQQYLDIKENYPDAFLLFRMGDFYELFYEDAVKAAQILEISLTSRNKNADNPIPMAGVPYHSAQSYIDVLVEMGYKVAIA
EQMEDPKQAVGVVKREVVQVITPGTVVDSSKPDNANNFLVAIDKAGSRFGLAYMDVSTGEFFATELDDFSSVCSEIQNLK
AREVVVGYDLPEADEQVLVKQLNLLLSKETEVYDDVHLIDTSLTDLESSVAGKLLQYVHRTQMRELSHLQKAQHYEIKDY
LQMSYATKSSLDLLENARTGKKHGSLFWLLDETKTAMGMRLLRTWIDRPLVNQAAIMERQNIIQVFLDNFFERSDLTESL
KGVYDIERLASRVSFGKANPKDLIQLGHTLAQVPVIKSILESFNDEALSRLLQELDALPELESLIRSAIDPDAPATITEG
GIIRAGFDETLDKYRKVMSEGTSWIADIEAKEREASGITTLKIDYNRKDGYYFHVTNSNLSLVPDHFFRKATLKNSERFG
TAELAKIEGEMLEAREKSSTLEYDIFMRVREQVERYIDRLQSLAKAIATVDVLQSLAVTAETNHYVRPVFNDEHRIVIDQ
GRHAVVEKVMGVQEYIPNTITFDSQTNVQLITGPNMSGKSTYMRQLALSVVMAQMGSYVPADSIDLPVFDAIYTRIGAAD
DLISGQSTFMVEMMEANQAIKRATPNSLIIFDELGRGTATYDGMALAQSIIEFIHDKVGAKTMFATHYHELTALSNTLTH
LVNVHVATLEKDGEVTFLHKIVDGPADKSYGIHVAKIAGLPADLLERADTILTQLEGETVTIQPQEKVSPQEKPATETHI
NEQISLFDDFTENPVLQELRDLDIYNMTPMQVMMAVADLKQKL

Nucleotide

• Length: 2532 bp

>NTDB_id=34154 SALIVB_RS00355 WP_414820285.1 57355..59886(+) (hexA) [Streptococcus salivarius CCHSS3]
ATGCAGCAGTATTTGGATATCAAGGAAAATTATCCAGATGCTTTTTTGCTCTTCCGTATGGGCGATTTTTACGAATTATT
TTACGAGGATGCCGTTAAGGCTGCCCAGATTTTGGAAATTAGCCTAACCAGTCGTAATAAGAACGCCGATAATCCCATTC
CTATGGCTGGTGTTCCTTATCATTCAGCTCAATCCTATATTGATGTCTTGGTTGAGATGGGCTACAAGGTAGCCATTGCT
GAGCAGATGGAGGATCCTAAACAGGCTGTTGGTGTGGTTAAGCGTGAGGTGGTTCAGGTTATCACGCCAGGGACAGTGGT
TGACAGTTCTAAACCTGATAATGCCAATAATTTCTTGGTAGCCATTGACAAGGCCGGAAGTCGATTCGGCCTGGCCTATA
TGGATGTGTCAACGGGTGAATTTTTTGCGACAGAGTTGGACGATTTCAGTTCAGTTTGTAGTGAAATTCAGAATCTTAAG
GCACGTGAAGTAGTGGTTGGTTATGATTTACCTGAAGCTGATGAACAAGTTTTGGTGAAGCAACTCAACCTTCTACTCTC
TAAGGAAACAGAGGTTTACGATGATGTCCACTTGATTGACACTAGCTTGACAGACTTGGAAAGCAGTGTAGCGGGTAAAC
TTCTCCAGTATGTGCACCGTACTCAGATGCGTGAGCTCAGCCATTTACAAAAGGCTCAGCACTATGAGATTAAGGATTAC
TTGCAGATGTCCTATGCGACCAAGTCGAGTTTGGATTTACTGGAAAATGCTAGAACAGGCAAGAAACACGGTTCTCTTTT
CTGGCTCTTGGATGAAACCAAGACAGCTATGGGAATGCGTCTCTTACGAACTTGGATTGACCGTCCTTTAGTGAATCAGG
CTGCAATCATGGAGCGCCAGAATATTATCCAAGTATTCTTGGACAATTTCTTCGAGCGTAGTGATCTGACTGAGAGTCTT
AAAGGGGTTTACGATATTGAGCGCTTGGCTAGTCGTGTTTCCTTCGGCAAGGCTAATCCTAAAGATTTGATTCAACTAGG
TCATACCCTAGCTCAGGTTCCAGTTATTAAGTCGATTTTGGAGTCTTTTAATGATGAGGCCTTGTCACGTCTTTTACAAG
AGTTAGATGCTCTGCCAGAATTAGAGAGTCTGATTCGGTCGGCTATTGATCCCGATGCTCCAGCAACCATTACAGAAGGT
GGCATTATCCGTGCTGGTTTTGATGAGACCTTGGACAAGTATCGCAAGGTGATGAGTGAGGGGACATCATGGATTGCAGA
CATCGAAGCCAAGGAACGTGAAGCGTCTGGTATTACAACACTAAAAATTGATTATAACCGTAAAGATGGTTATTACTTCC
ATGTGACCAACTCTAACCTTAGCTTGGTTCCTGACCATTTCTTCCGCAAGGCAACCTTGAAAAATTCAGAGCGCTTTGGA
ACTGCTGAGTTGGCTAAGATTGAAGGTGAAATGCTTGAGGCACGTGAAAAATCATCAACGCTAGAGTATGATATTTTCAT
GCGTGTCCGTGAGCAGGTTGAACGCTATATTGACCGTCTGCAATCTTTGGCTAAGGCCATTGCGACAGTCGATGTGCTTC
AGAGTTTGGCAGTTACAGCTGAGACTAATCATTATGTTCGTCCTGTGTTCAATGATGAGCATCGTATCGTTATTGATCAA
GGGCGTCATGCAGTGGTTGAGAAGGTTATGGGCGTTCAGGAATACATTCCAAACACGATTACCTTTGACAGTCAGACCAA
TGTTCAGCTCATCACAGGACCAAATATGAGTGGTAAATCTACTTATATGCGTCAGTTGGCCTTGTCAGTCGTTATGGCTC
AGATGGGCTCTTACGTGCCAGCAGATAGTATTGATTTGCCAGTTTTTGACGCCATCTATACACGTATTGGTGCTGCAGAT
GACCTGATTTCAGGTCAGTCGACCTTCATGGTTGAGATGATGGAGGCTAATCAGGCCATTAAGCGAGCGACACCTAATTC
CTTGATTATTTTTGATGAGTTGGGGCGTGGGACAGCCACCTATGATGGTATGGCTTTGGCCCAGTCTATCATTGAGTTTA
TTCATGACAAGGTGGGGGCTAAAACCATGTTTGCTACCCATTATCATGAGTTGACAGCCCTGTCAAATACTTTGACACAC
CTTGTCAACGTTCATGTGGCGACACTTGAAAAGGACGGAGAGGTGACTTTCCTTCACAAGATTGTCGATGGCCCAGCCGA
TAAATCTTACGGTATTCATGTAGCTAAGATTGCAGGTTTACCAGCAGATTTACTGGAACGTGCTGACACCATCTTGACAC
AATTAGAGGGCGAGACAGTTACCATCCAACCTCAGGAAAAGGTATCGCCTCAAGAGAAGCCTGCCACTGAAACGCATATC
AACGAGCAAATCTCTCTCTTTGATGATTTTACTGAAAATCCGGTTCTTCAAGAGTTACGTGATTTGGATATTTACAATAT
GACACCGATGCAGGTCATGATGGCTGTAGCAGATTTGAAACAGAAACTATAA

Domains

Predicted by InterProScan.

• MutS domain V (MutS_V) (590-776)

• MutS domain III (MutS_III) (247-537)

• MutS domain I (MutS_I) (1-109)

• MutS family domain IV (MutS_IV) (406-496)

• MutS domain II (MutS_II) (117-230)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	73.815	100	0.739
mutS	Pseudomonas stutzeri strain ATCC 17587	35.731	100	0.365