Detailed information NTG0341498

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: ETT63_RS06975
• Genome accession: NZ_CP035436
• Coordinates: 1370471..1371472 (-)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain emm89.14
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1365471..1376472

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ETT63_RS06960 (ETT63_06960)	thrS	1365641..1367584 (-)	1944	WP_002985672.1	threonine--tRNA ligase	-
ETT63_RS06965 (ETT63_06965)	-	1368006..1369340 (-)	1335	WP_002994187.1	glycosyltransferase family 4 protein	-
ETT63_RS06970 (ETT63_06970)	-	1369342..1370340 (-)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
ETT63_RS06975 (ETT63_06975)	ccpA	1370471..1371472 (-)	1002	WP_002985680.1	catabolite control protein A	Regulator
ETT63_RS06980 (ETT63_06980)	-	1371646..1372731 (+)	1086	WP_002985682.1	aminopeptidase P family protein	-
ETT63_RS06985 (ETT63_06985)	-	1372780..1373445 (+)	666	WP_031488435.1	NAD(P)H-dependent oxidoreductase	-
ETT63_RS06990 (ETT63_06990)	-	1373456..1373833 (+)	378	WP_002985686.1	VOC family protein	-
ETT63_RS06995 (ETT63_06995)	-	1373978..1374904 (+)	927	WP_110002748.1	glycosyltransferase family 2 protein	-
ETT63_RS07000 (ETT63_07000)	-	1375115..1375798 (+)	684	WP_053308560.1	DUF969 domain-containing protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=341498 ETT63_RS06975 WP_002985680.1 1370471..1371472(-) (ccpA) [Streptococcus pyogenes strain emm89.14]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=341498 ETT63_RS06975 WP_002985680.1 1370471..1371472(-) (ccpA) [Streptococcus pyogenes strain emm89.14]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCTGCTATGTACAAATATAATATTGTGCTTGCCTCCAGCGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAATTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGTTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACTAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559