Detailed information NTG0341446

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: ETT64_RS07025
• Genome accession: NZ_CP035435
• Coordinates: 1359222..1360223 (-)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain emm64.3
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1354222..1365223

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ETT64_RS07010 (ETT64_07010)	thrS	1354392..1356335 (-)	1944	WP_032464864.1	threonine--tRNA ligase	-
ETT64_RS07015 (ETT64_07015)	-	1356757..1358091 (-)	1335	WP_002994187.1	glycosyltransferase family 4 protein	-
ETT64_RS07020 (ETT64_07020)	-	1358093..1359091 (-)	999	WP_136262551.1	glycosyltransferase family 4 protein	-
ETT64_RS07025 (ETT64_07025)	ccpA	1359222..1360223 (-)	1002	WP_002985680.1	catabolite control protein A	Regulator
ETT64_RS07030 (ETT64_07030)	-	1360397..1361482 (+)	1086	WP_002985682.1	aminopeptidase P family protein	-
ETT64_RS07035 (ETT64_07035)	-	1361531..1362196 (+)	666	WP_002985684.1	NAD(P)H-dependent oxidoreductase	-
ETT64_RS07040 (ETT64_07040)	-	1362207..1362584 (+)	378	WP_020904973.1	VOC family protein	-
ETT64_RS07045 (ETT64_07045)	-	1362729..1363655 (+)	927	WP_002994177.1	glycosyltransferase family 2 protein	-
ETT64_RS07050 (ETT64_07050)	-	1363866..1364549 (+)	684	WP_002994173.1	DUF969 domain-containing protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=341446 ETT64_RS07025 WP_002985680.1 1359222..1360223(-) (ccpA) [Streptococcus pyogenes strain emm64.3]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=341446 ETT64_RS07025 WP_002985680.1 1359222..1360223(-) (ccpA) [Streptococcus pyogenes strain emm64.3]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
TAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAGTTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTATC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGTTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCGGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559