Detailed information NTG0034140

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: SGPB_RS09950
• Genome accession: NC_015600
• Coordinates: 2026876..2029446 (-)
• Length: 856 a.a.
• NCBI ID: WP_013852331.1
• Uniprot ID: F5X3U0
• Organism: Streptococcus pasteurianus ATCC 43144
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 2021876..2034446

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SGPB_RS09925 (SGPB_1953)	-	2022385..2022687 (-)	303	WP_230321699.1	hypothetical protein	-
SGPB_RS11555 (SGPB_1955)	-	2022988..2023164 (-)	177	WP_230321700.1	hypothetical protein	-
SGPB_RS09935 (SGPB_1956)	-	2023311..2024162 (+)	852	WP_013852329.1	helix-turn-helix domain-containing protein	-
SGPB_RS09940 (SGPB_1957)	ruvA	2024242..2024835 (-)	594	WP_003066922.1	Holliday junction branch migration protein RuvA	Machinery gene
SGPB_RS09945 (SGPB_1958)	hexB	2024837..2026759 (-)	1923	WP_013852330.1	DNA mismatch repair endonuclease MutL	Machinery gene
SGPB_RS09950 (SGPB_1959)	hexA	2026876..2029446 (-)	2571	WP_013852331.1	DNA mismatch repair protein MutS	Machinery gene
SGPB_RS09955 (SGPB_1960)	-	2029433..2029789 (-)	357	WP_003066927.1	YlbF family regulator	-
SGPB_RS09960 (SGPB_1961)	argR	2029786..2030223 (-)	438	WP_003066930.1	arginine repressor	-
SGPB_RS09965 (SGPB_1962)	argS	2030414..2032105 (+)	1692	WP_013852332.1	arginine--tRNA ligase	-
SGPB_RS09970 (SGPB_1963)	-	2032217..2032510 (+)	294	WP_013852333.1	bacteriocin immunity protein	-
SGPB_RS09975 (SGPB_1964)	-	2032552..2034057 (-)	1506	WP_013852334.1	prolyl oligopeptidase family serine peptidase	-

Sequence

Protein

• Length: 856 a.a.
• Molecular weight: 96080.51 Da
• Isoelectric Point: 4.8579

>NTDB_id=34140 SGPB_RS09950 WP_013852331.1 2026876..2029446(-) (hexA) [Streptococcus pasteurianus ATCC 43144]
MTKDKISPGMQQYLDVKKDYPDAFLLFRMGDFYELFYDDAVKAAQILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLV
EMGYKVAIAEQMEDPKQAVGVVKREVVQVITPGTAVDSSKPDNANNFLVAIDSDGKTFGLAYMDVSTGEFFSTSLSDFTS
LRSEILNLKAREIVVGYELSETEQHSLVKQLNLLLSFEQERYEDVHLIDPDLTALEISAAEKLLQYVHTTQKRELSHLQK
LVHYEIKDYLQMSYTTKSSLDLLENARTSKKHGSLYWLLDETKTAMGMRLLRNWIDRPLVNQAQIEERQNIVQVFLDNFF
ERSDLTDSLKGVYDIERLASRVSFGKANPKDLLQLGHTLAQVPRIKAILESFESPHLDKLVNSIDTLPELESLIRSAIDP
DAPAVITEGSIIRTGFDEILDKYRKVMREGTSWIAEVETKERAASGITNLKIDYNKKDGYYFHVTNSNLSLVPDYFFRKA
TLKNSERFGTAELAKIEGEMLEAREQSASLEYDIFMRVRGQVERYITRLQDLAKALSSVDVLQSLAVVAENNHYVRPTFN
DSHEIKIEKGRHAVVEKVMGTQEYIPNTITFDADINIQLITGPNMSGKSTYMRQLALTVIMAQMGSYVAAESVNLPVFDA
IFTRIGAADDLISGQSTFMVEMMEANQAIKRASSQSLILFDELGRGTATYDGMALAQSIIEYIHDHIGAKTMFATHYHEL
TALSTILTHLVNVHVATLEKNGDVTFLHKIAEGPADKSYGVHVAKIAGLPEELLQRADSILTNLESGAAQLQLTPEVEAE
PITIKSEVAEPVAEQLSLFADDSSNQEVIKVLKKVDLMNLTPMQAMNVIYELKNML

Nucleotide

• Length: 2571 bp

>NTDB_id=34140 SGPB_RS09950 WP_013852331.1 2026876..2029446(-) (hexA) [Streptococcus pasteurianus ATCC 43144]
ATGACAAAAGATAAAATTTCTCCAGGCATGCAACAGTATTTGGACGTAAAAAAAGATTATCCAGATGCTTTTTTACTTTT
CCGCATGGGAGACTTTTATGAATTATTTTATGATGATGCGGTTAAAGCTGCACAAATTTTAGAGATTAGTTTAACTAGTC
GTAATAAAAATGCTGACAACCCAATTCCAATGGCAGGTGTGCCTTATCATTCTGCGCAACAATACATTGATGTATTAGTG
GAAATGGGTTACAAGGTGGCAATTGCTGAGCAAATGGAAGACCCAAAACAAGCCGTCGGTGTGGTTAAACGTGAAGTCGT
TCAAGTGATTACGCCAGGGACAGCTGTCGATTCCTCTAAACCAGATAATGCTAACAATTTCTTGGTGGCTATTGATTCTG
ACGGCAAAACGTTTGGGCTAGCCTATATGGACGTGTCAACAGGTGAATTTTTCTCAACAAGTCTTTCTGATTTTACAAGC
CTTAGAAGTGAAATTCTGAACCTTAAAGCGCGTGAAATCGTTGTTGGTTATGAGCTTTCTGAAACAGAGCAACATAGCTT
AGTCAAACAATTAAATTTACTCTTATCGTTTGAACAAGAACGTTATGAAGATGTGCATTTAATCGACCCAGATTTAACAG
CCTTAGAAATTTCAGCAGCTGAAAAATTGCTACAATACGTTCATACAACGCAAAAACGTGAGCTAAGCCATTTGCAAAAA
TTGGTTCATTATGAAATCAAAGATTACTTGCAAATGTCTTACACGACAAAATCTAGTTTGGATTTATTAGAAAATGCTCG
AACAAGTAAAAAACATGGTAGCCTTTATTGGTTACTAGATGAAACTAAAACGGCTATGGGAATGCGTCTGTTGCGTAATT
GGATTGACCGTCCTTTGGTGAACCAAGCACAGATTGAAGAGCGCCAAAATATTGTTCAAGTTTTCCTAGATAATTTCTTT
GAGCGTAGTGATTTGACGGATAGTCTCAAAGGTGTTTATGATATTGAACGTCTAGCGAGTCGTGTGTCATTTGGAAAAGC
TAATCCAAAAGATTTATTACAACTCGGTCATACCTTGGCACAAGTGCCAAGGATTAAGGCGATTTTAGAATCGTTTGAAA
GCCCTCACCTTGACAAGCTTGTCAATAGCATTGACACTTTGCCAGAACTAGAATCGTTGATTCGATCAGCTATTGACCCA
GATGCTCCTGCTGTTATCACAGAAGGCAGCATTATCCGTACAGGTTTTGATGAGATTTTGGATAAATACCGTAAGGTTAT
GCGCGAGGGGACTAGTTGGATTGCAGAAGTTGAAACTAAGGAACGTGCTGCAAGTGGGATTACCAATCTAAAAATTGATT
ATAATAAAAAAGATGGATACTATTTCCATGTAACAAATTCCAATCTCTCTCTAGTGCCAGATTATTTCTTCCGCAAGGCA
ACGTTGAAAAATTCAGAGCGTTTCGGAACGGCAGAATTGGCTAAAATTGAAGGTGAGATGTTGGAGGCGCGTGAGCAATC
AGCAAGCTTAGAATATGATATTTTTATGCGCGTTCGCGGACAAGTTGAGCGTTACATTACTCGTTTGCAAGACTTGGCTA
AGGCGCTTTCAAGCGTTGACGTTTTACAAAGTTTAGCCGTTGTTGCAGAAAATAATCATTATGTTCGTCCAACATTCAAC
GATAGCCATGAGATTAAAATTGAAAAAGGTCGTCATGCGGTCGTTGAAAAAGTCATGGGAACGCAAGAATATATTCCTAA
TACGATTACGTTTGATGCCGATATCAACATTCAGCTGATTACTGGTCCAAATATGAGTGGTAAATCAACTTATATGCGTC
AACTTGCCTTGACCGTTATTATGGCTCAAATGGGGTCTTACGTAGCTGCTGAAAGTGTCAATTTACCAGTATTTGATGCG
ATTTTCACGCGTATTGGTGCGGCAGATGATTTGATTTCAGGACAGTCAACGTTTATGGTGGAAATGATGGAAGCTAACCA
AGCTATCAAACGTGCAAGTTCTCAATCCTTGATTCTTTTTGATGAGCTAGGTCGTGGTACAGCAACCTATGACGGTATGG
CTTTGGCGCAATCAATCATTGAATATATCCATGATCATATTGGTGCAAAGACCATGTTTGCAACCCATTATCATGAGTTG
ACAGCTTTGTCAACGATCTTGACGCACCTTGTCAATGTTCACGTTGCGACTCTTGAGAAAAATGGTGATGTGACTTTTCT
TCATAAAATTGCAGAAGGTCCAGCAGACAAATCTTACGGGGTTCATGTTGCAAAAATTGCTGGTTTACCAGAAGAATTAT
TACAACGTGCGGACAGTATCTTGACAAATTTAGAATCAGGTGCTGCGCAGCTTCAATTGACCCCTGAGGTGGAAGCTGAG
CCAATTACTATAAAATCAGAAGTAGCAGAACCAGTGGCAGAGCAACTAAGTTTATTTGCTGATGACTCATCTAATCAAGA
AGTGATTAAAGTACTCAAAAAAGTTGATTTGATGAATTTAACACCAATGCAAGCCATGAATGTTATTTATGAATTAAAAA
ATATGTTGTAA

Domains

Predicted by InterProScan.

• MutS domain I (MutS_I) (8-118)

• MutS domain III (MutS_III) (256-546)

• MutS domain II (MutS_II) (126-239)

• MutS family domain IV (MutS_IV) (415-505)

• MutS domain V (MutS_V) (599-785)

3D structure

• AlphaFold DB: F5X3U0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	71.612	100	0.716
mutS	Pseudomonas stutzeri strain ATCC 17587	37.586	100	0.382