Detailed information NTG0341107

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: ETT70_RS02300
• Genome accession: NZ_CP035429
• Coordinates: 415604..416605 (+)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain emmNA
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 410604..421605

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ETT70_RS02275 (ETT70_02270)	-	411278..411961 (-)	684	WP_111681010.1	DUF969 domain-containing protein	-
ETT70_RS02280 (ETT70_02275)	-	412172..413098 (-)	927	WP_136275785.1	glycosyltransferase family 2 protein	-
ETT70_RS02285 (ETT70_02280)	-	413243..413620 (-)	378	WP_002985686.1	VOC family protein	-
ETT70_RS02290 (ETT70_02285)	-	413631..414296 (-)	666	WP_002985684.1	NAD(P)H-dependent oxidoreductase	-
ETT70_RS02295 (ETT70_02290)	-	414345..415430 (-)	1086	WP_136275786.1	aminopeptidase P family protein	-
ETT70_RS02300 (ETT70_02295)	ccpA	415604..416605 (+)	1002	WP_002985680.1	catabolite control protein A	Regulator
ETT70_RS02305 (ETT70_02300)	-	416736..417734 (+)	999	WP_002990703.1	glycosyltransferase family 4 protein	-
ETT70_RS02310 (ETT70_02305)	-	417736..419070 (+)	1335	WP_030127184.1	glycosyltransferase family 4 protein	-
ETT70_RS02315 (ETT70_02310)	thrS	419492..421435 (+)	1944	WP_136119540.1	threonine--tRNA ligase	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=341107 ETT70_RS02300 WP_002985680.1 415604..416605(+) (ccpA) [Streptococcus pyogenes strain emmNA]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=341107 ETT70_RS02300 WP_002985680.1 415604..416605(+) (ccpA) [Streptococcus pyogenes strain emmNA]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAATTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGTTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACTAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAATTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559