Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   F4V40_RS23390 Genome accession   NZ_CP044145
Coordinates   4444029..4444619 (-) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli O157 strain AR-0428     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4439029..4449619
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  F4V40_RS23375 uhpT 4439669..4441060 (-) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -
  F4V40_RS23380 uhpC 4441198..4442517 (-) 1320 WP_001301991.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  F4V40_RS23385 uhpB 4442527..4444029 (-) 1503 WP_001303725.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  F4V40_RS23390 letA 4444029..4444619 (-) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  F4V40_RS23395 - 4444781..4445884 (-) 1104 WP_001089794.1 hypothetical protein -
  F4V40_RS23400 - 4446492..4446974 (-) 483 WP_000229982.1 hypothetical protein -
  F4V40_RS23405 - 4447122..4447775 (-) 654 WP_000168040.1 hypothetical protein -
  F4V40_RS23410 ilvN 4448038..4448328 (-) 291 WP_001181706.1 acetolactate synthase small subunit -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=341090 F4V40_RS23390 WP_000633668.1 4444029..4444619(-) (letA) [Escherichia coli O157 strain AR-0428]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=341090 F4V40_RS23390 WP_000633668.1 4444029..4444619(-) (letA) [Escherichia coli O157 strain AR-0428]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGTTGCTGGGGCTGGAACCTGATTT
GCAAGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAGCTGCTAAGCCAGCTGCCGAAAGGTATGGCGACAATTATGCTCTCCGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCGCGTGGCTTTCTCTCCAAGCGTTGTAGCCCTGACGA
ACTGATTGCTGCGGTGCATACGGTTGCCACAGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GCCAGGACCCACTAACCAAACGTGAACGGCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTTGA
ACTGGCGCGCCGTATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378

Multiple sequence alignment