Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   F4V42_RS13050 Genome accession   NZ_CP044140
Coordinates   2462449..2463081 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli O157 strain AR-0430     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2457449..2468081
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  F4V42_RS13025 yhfG 2457581..2457748 (+) 168 WP_000736862.1 YhfG family protein -
  F4V42_RS13030 fic 2457738..2458340 (+) 603 WP_001280650.1 putative adenosine monophosphate-protein transferase Fic -
  F4V42_RS13035 pabA 2458372..2458935 (+) 564 WP_000601867.1 aminodeoxychorismate synthase component 2 -
  F4V42_RS13040 argD 2459021..2460241 (+) 1221 WP_000963819.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  F4V42_RS13045 yhfK 2460308..2462398 (-) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  F4V42_RS13050 crp 2462449..2463081 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  F4V42_RS13055 yhfA 2463383..2463787 (+) 405 WP_001148908.1 OsmC family protein -
  F4V42_RS13060 prkB 2463842..2464711 (-) 870 WP_001274677.1 phosphoribulokinase -
  F4V42_RS13065 yheU 2464765..2464983 (-) 219 WP_000907085.1 YheU family protein -
  F4V42_RS13070 yheT 2464977..2465999 (-) 1023 WP_000057377.1 hydrolase -
  F4V42_RS13075 yheS 2465999..2467912 (-) 1914 WP_000634798.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=340920 F4V42_RS13050 WP_000242755.1 2462449..2463081(-) (crp) [Escherichia coli O157 strain AR-0430]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=340920 F4V42_RS13050 WP_000242755.1 2462449..2463081(-) (crp) [Escherichia coli O157 strain AR-0430]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCTGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTCAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTTGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment