Detailed information NTG0339873

Bioinformatically predicted

Overview

• Name: comEA
• Type: Machinery gene
• Locus tag: ES968_RS13015
• Genome accession: NZ_CP035395
• Coordinates: 2430280..2430897 (-)
• Length: 205 a.a.
• NCBI ID: WP_046160608.1
• Uniprot ID: -
• Organism: Bacillus subtilis strain SRCM103697
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2425280..2435897

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ES968_RS12985 (ES968_12985)	rpsT	2425581..2425847 (+)	267	WP_003229989.1	30S ribosomal protein S20	-
ES968_RS12990 (ES968_12990)	holA	2425862..2426905 (-)	1044	WP_029317888.1	DNA polymerase III subunit delta	-
ES968_RS12995 (ES968_12995)	-	2426945..2427058 (-)	114	WP_122060479.1	hypothetical protein	-
ES968_RS13000 (ES968_13000)	yqzM	2427135..2427269 (+)	135	WP_003229983.1	YqzM family protein	-
ES968_RS13005 (ES968_13005)	comEC	2427310..2429640 (-)	2331	WP_046160607.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
ES968_RS13010 (ES968_13010)	comEB	2429644..2430213 (-)	570	WP_003229978.1	ComE operon protein 2	-
ES968_RS13015 (ES968_13015)	comEA	2430280..2430897 (-)	618	WP_046160608.1	competence protein ComEA	Machinery gene
ES968_RS13020 (ES968_13020)	comER	2430981..2431802 (+)	822	WP_032726195.1	late competence protein ComER	-
ES968_RS13025 (ES968_13025)	yqeM	2431868..2432611 (-)	744	WP_046160609.1	class I SAM-dependent methyltransferase	-
ES968_RS13030 (ES968_13030)	rsfS	2432608..2432964 (-)	357	WP_014480315.1	ribosome silencing factor	-
ES968_RS13035 (ES968_13035)	yqeK	2432982..2433542 (-)	561	WP_014480316.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
ES968_RS13040 (ES968_13040)	nadD	2433532..2434101 (-)	570	WP_041333756.1	nicotinate-nucleotide adenylyltransferase	-
ES968_RS13045 (ES968_13045)	yhbY	2434113..2434403 (-)	291	WP_003226133.1	ribosome assembly RNA-binding protein YhbY	-
ES968_RS13050 (ES968_13050)	aroE	2434397..2435239 (-)	843	WP_029317883.1	shikimate dehydrogenase	-

Sequence

Protein

• Length: 205 a.a.
• Molecular weight: 21738.48 Da
• Isoelectric Point: 4.7284

>NTDB_id=339873 ES968_RS13015 WP_046160608.1 2430280..2430897(-) (comEA) [Bacillus subtilis strain SRCM103697]
MNWLNQHKKAIVLAASAAVFTAIMIFLATGKNKEPVKQAVPTEAENTVVKQEANNDESSETIVIDIKGAVQHPGVYEMRT
GDRVSQAIEKAGGTSEQADEAQVNLAEILQDGTVVYIPKKGEETAVQQGGGGSVQSDGGKGALVNINTATLEELQGISGV
GPSKAEAIIAYREENGRFQTIEEITKVSGIGEKLFEKIKSSITVK

Nucleotide

• Length: 618 bp

>NTDB_id=339873 ES968_RS13015 WP_046160608.1 2430280..2430897(-) (comEA) [Bacillus subtilis strain SRCM103697]
ATGAATTGGTTGAATCAGCATAAGAAAGCAATTGTTTTAGCGGCTTCTGCGGCTGTTTTCACAGCGATTATGATCTTTCT
GGCCACAGGGAAAAATAAAGAGCCGGTGAAGCAAGCTGTACCAACAGAGGCAGAAAATACAGTGGTAAAGCAGGAAGCAA
ACAACGACGAGTCAAGCGAAACAATTGTGATAGACATCAAAGGTGCTGTTCAGCATCCTGGAGTTTATGAAATGCGAACA
GGGGACAGAGTATCTCAGGCAATTGAGAAAGCGGGCGGGACCAGTGAACAAGCAGACGAAGCGCAAGTAAATTTGGCGGA
GATTTTGCAGGACGGGACAGTGGTGTACATCCCGAAAAAGGGAGAGGAAACAGCAGTGCAGCAAGGTGGCGGAGGGTCTG
TCCAAAGCGATGGAGGGAAGGGAGCGCTGGTGAATATCAATACAGCAACCTTAGAGGAGTTACAAGGCATCTCAGGGGTG
GGGCCATCCAAAGCTGAAGCTATTATTGCATACCGGGAAGAAAACGGGCGTTTCCAAACAATTGAAGAAATCACTAAGGT
TTCAGGAATAGGTGAAAAGTTATTTGAGAAAATAAAGTCTTCCATTACAGTAAAGTGA

Domains

Predicted by InterproScan.

• SLBB domain (SLBB) (63-118)

• Helix-hairpin-helix motif (HHH_3) (142-203)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA	Bacillus subtilis subsp. subtilis str. 168	97.561	100	0.976
comEA	Staphylococcus aureus MW2	35.909	100	0.385
comEA	Staphylococcus aureus N315	35	100	0.376